223. Why Creatine Monohydrate Isn’t Enough Anymore

“Destroyed by the gut.” “Zero absorption.” “Only injectables work.” This is BS. In this episode, I break down why oral peptides aren’t just working, they’re evolving. I cover the science, the delivery tech, and the results I’ve lived through: cartilage regrowth, hormonal optimization, cognitive firepower. You’ll learn how short-chain peptides bypass gut breakdown via PEPT1. Why nano-carriers, mucoadhesive polymers, and smart pH triggers are rewriting absorption. And why anyone still parroting the “oral doesn’t work” myth is stuck in 2005. I show you my travel peptide stack, how I keep everything cold, and why oral bioregulators like Sigma, Testolutin, and Biomind are now staples in my rotation. This isn’t hype. This is recovery, immunity, and performance…elevated. What's Discussed: (00:06) Oral Peptides: Why the “Destroyed by the Gut” Claim is BS (02:42) My Travel Stack: Fridge, Injectables, and Immune Armor (04:39) Brain on Fire: The Peptides That Keep You Sharp (08:19) Biohacking Absorption: How Oral Peptides Actually Work (16:54) What Makes Next-Level Recovery My Go-To for Gut Health: Glutamine and Imuno-IGG from Unmatched Supplements: https://www.unmatchedsupps.com/collections/digestion-gut-health Find more from Kris: Website: https://www.krisgethin.com/ Website:https://www.unmatchedsupps.com Instagram: @krisgethin  Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred    

​​You take creatine. You think it’s working. But if you’re bloated, cramping, or seeing zero gains, you’re not absorbing it right. Here’s the truth: monohydrate saturates one transport pathway. Once that’s full, you're done. Up to 30% of users feel nothing. Add GI issues and brain access problems, and you're building strength on a weak foundation. In this episode, I break down CreGAAtine, a next-gen formula with creatine monohydrate, GAA, and B vitamins. It hits four pathways, not one. That means better muscle saturation, stronger brain uptake, and zero bloating. I cover absorption, ATP regeneration, neuroprotection, and why this crushes the “non-responder” excuse. You get more power, more cognitive resilience, and faster recovery, without these side effects. I show you how I take it, why it works year-round, and how it fits into a performance-first lifestyle. Listen in. Then upgrade your creatine. Your strength, brain, and gut will thank you. What's Discussed: (00:01) Evolution of Creatine (01:22) Limitations of Monohydrate (04:13) Brain Absorption & Non-Responders (05:26) What Makes CreGAAtine Different (11:42) Benefits of Creatine Supplementation Thank you to our sponsors:    NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/    My Go-To Creatine: CreGAAtine from Unmatched Supplements: https://www.unmatchedsupps.com/cregaatine-capsules Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin   2 Shred: https://www.unmatchedsupps.com/products/2shred   

My Go-To Protein: UK Pasture-Raised Whey Isolate from Unmatched Supplements SHOP HERE: (BOGO 50% OFF SALE HAPPENING NOW): https://www.vitaminshoppe.com/p/isolate-grass-fed-whey-protein-rich-chocolate-2-lb-powder/unm-14114 You check the label. It says “grass-fed.” You think you’re getting the cleanest, most nutrient-rich protein possible. But here’s the truth: in the U.S., that label can mean almost nothing. Loopholes, grain finishing, inconsistent nutrient profiles, even hidden contaminants. And if you’re using that protein daily? You’re building your results on a shaky foundation. In this episode, I break down the real difference between UK/Irish pasture-raised whey isolate and most U.S. “grass-fed” protein. You’ll learn why sourcing, animal welfare, and processing methods matter for muscle growth, fat loss, recovery, and long-term health. We’ll talk nutrient density, bioactive fractions, contamination risks, sweetener choices, and how to spot marketing tricks designed to make cheap protein look premium. I’ll show you exactly what I use, why I use it, and how to make sure your protein works with your health, not against it. No fillers. No hype. Just facts you can use to choose better, recover faster, and perform longer. Listen in. Then upgrade your protein. What's Discussed: 00:01 – Why “grass-fed” on the label might not mean what you think 03:01 – The hidden factor that makes UK whey stand out 10:44 – The sweetener choice that could sabotage your results   My Go-To Protein: UK Pasture-Raised Whey Isolate from Unmatched Supplements SHOP HERE: (BOGO 50% OFF SALE HAPPENING NOW): https://www.vitaminshoppe.com/p/isolate-grass-fed-whey-protein-rich-chocolate-2-lb-powder/unm-14114 Thank you to our sponsors:    NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/    Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin   2 Shred: https://www.unmatchedsupps.com/products/2shred

You’ve been told you can’t have both. That you need to choose between getting lean or staying muscular. That’s BS and in this episode, I break down the exact strategies I use with high-performance clients around the world to help them burn fat without sacrificing size, strength, or muscle mass. You’ll learn how to leverage high-protein intake, amino acid timing, heat and cold therapy, cutting-edge peptides, fat-loss supplements, and deep sleep optimization, all backed by science and proven in practice. This is about performing at your peak, recovering faster, and protecting your hard-earned muscle while cutting down. No fluff. No shortcuts. Just precision protocols that get real results. Listen in, and upgrade your cut. What's Discussed: 00:26 – Burn Fat Without Shrinking: The Real Strategy 02:33 – Why High Protein Protects Muscle in a Cut 04:41 – How to Stay Anabolic During Fasted Cardio 06:08 – Use Sauna + Ice to Trigger Fat Loss and Recovery 13:36 – Poor Sleep Is Killing Your Gains—Here’s Why Thank you to our sponsors:    NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/ Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin 2 Shred: https://www.unmatchedsupps.com/products/2shred   

You’ve followed every program. Taken every “science-backed” supplement. Tracked your sleep, steps, macros, and macros again. But results? Still inconsistent. Still frustrating. Still not reflecting the effort. That’s because you’re using generic tools for a highly specific machine, your body. In this episode, I walk you through the real game-changer: data-driven personalization. DNA testing. You’ll learn how to stop wasting time on plans that weren’t made for you, and start building a system based on your unique biology.  I’ll share the tools I use with VIP+ clients and myself to optimize recovery, cut fat, gain muscle, and extend healthspan well past 50. This isn’t optional anymore. If you want elite results, you need elite intel. No fluff. No hype. Just hard data and harder action. Listen in. Then upgrade everything. What's Discussed: 01:20 – Why cookie-cutter diets and generic plans are dead 03:55 – The real power of DNA: what your genes say about your gains 06:50 – How CGMs expose “healthy” foods that sabotage your energy 10:30 – Using HRV, blood work, and wearables to decide when to push or pull back 12:40 – Client case studies: stress, stubborn fat, and reversing biological age Thank you to our sponsors:    NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/  Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin  2 Shred: https://www.unmatchedsupps.com/products/2shred   

You train hard. You track every damn macro. You’re doing the double cardio grind. But your body still looks soft, flat, or watery. Something’s off. In this episode, I break down 11 reasons your physique isn’t changing—even though you’re doing “everything right.” Trash protein quality. Chronic inflammation. Hormones out of whack. Training without progression. Stress jacking your cortisol through the roof. This isn’t motivational fluff. It’s physiological fact. You don’t rise to the level of your motivation. You fall to the level of your systems. Fix what’s broken. Apply what works. Listen in and level up. What’s discussed: (00:05) You’re Doing Everything Right—So Why Do You Still Look Soft? (02:18) Hitting Your Protein Target? Doesn’t Mean You’re Building Muscle (05:13) Starving Yourself Shredded? Here’s Why That Backfires (10:06) Low Libido. Brain Fog. Fat Gain. Your Hormones Are Screaming (16:01) Still Not Lean? Cold, Sleep, and Stress Might Be the Missing Link Thank you to our sponsors:    NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/    Find more from Kris: Website: https://www.krisgethin.com/   Instagram: https://www.instagram.com/krisgethin/   Youtube: https://www.youtube.com/krisgethin   2 Shred: https://www.unmatchedsupps.com/products/2shred   

Is GLP-3s the Next Evolution in Peptides? Here’s What You’re Not Hearing Everyone’s obsessed with GLP-1s like GLP-1. But what if there’s a better option with more benefits, fewer side effects, and real potential for body recomposition, brain health, and gut repair? It’s called GLP-3 peptides, also known as Retatrutide, and most people haven’t even heard of it yet. In this episode, I break down why GLP-1s aren’t the miracle drugs people think they are. They suppress appetite, yes, but at the cost of muscle mass, nutrient absorption, and long-term metabolic health. GLP-3s work differently. It improves gut integrity, boosts BDNF for brain performance, enhances metabolic flexibility, and reduces inflammation at the root. I also walk through how I use GLP-3s in client protocols, from microdosing to blood work analysis, and how it fits into a serious longevity strategy. If you care about more than just weight loss, this is the peptide you need to understand. Listen to the full breakdown. This one matters. We Also Discuss: (00:04) Why GLP-3s are the peptide nobody’s talking about, yet (03:52) What is GLP-3s and how it differs from GLP-1 (07:22) Gut health and healing leaky gut with GLP-3s (10:46) Brain health, BDNF, and cognitive benefits (20:35) GLP-3s for longevity, inflammation, and full-body optimization (24:00) Final thoughts, client protocols, and how to get started with GLP-3s Thank you to our sponsors:    NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/    Find more from Kris: Website: https://www.krisgethin.com/   Instagram: https://www.instagram.com/krisgethin/   Youtube: https://www.youtube.com/krisgethin   2 Shred: https://www.unmatchedsupps.com/products/2shred   

Is GLP-2s the next level in fat loss or just another excuse to skip the work? In this episode of the Kris Gethin Podcast, I break down the most advanced GLP peptide on the market right now. You’ll learn how this dual-action compound hits both GLP-1s and GIP receptors to accelerate fat loss, crush hunger, and improve metabolic function faster than older GLP-1s. I walk you through the real-world results my clients are seeing: 15 to 22 percent bodyweight drops, better blood sugar control, and renewed energy. But I also pull back the curtain on the downsides. Nausea. Gut issues. Muscle loss. All of it can happen. You’ll discover how to use GLP-2s the right way. I also share a powerful transformation story from a friend who dropped over 130 pounds and built a physique he never thought possible. This episode gives you the tools to use modern science as fuel for your transformation, not a crutch to avoid effort. Listen now. Apply what you learn. And stop messing around. We Also Discuss: 01:27: How GLP-2s work: dual agonist targeting GLP-1s and GIP 03:46: Why GLP-2s outperform GLP-1s in fat loss and blood sugar control 05:52: GLP-2s vs GLP-1s: side-by-side comparison of results and side effects 08:26: The non-negotiables: training, diet, and recovery on GLP peptides 12:41: Real transformation: how one client lost 130 lbs and built muscle Thank You To our Sponsors: NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/    Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin  2 Shred: https://www.unmatchedsupps.com/products/2shred

Are GLP-1s like Ozempic and Mounjaro the future of fat loss, or just another excuse to skip the hard work? In this episode of the Kris Gethin Podcast, I break down the truth behind the hype. These drugs were made for managing blood sugar in type 2 diabetics, but now they’re being abused as quick fixes by people who refuse to lift, eat real food, or build discipline.   I explain exactly how GLP-1s work, how they suppress appetite, regulate insulin, slow gastric emptying, and why that means absolutely nothing if you’re not strength training or hitting your protein targets.    You’ll learn the science-backed risks: loss of lean muscle mass, slower metabolism, nutrient deficiencies, and long-term hormonal disruption. I also cover the hidden benefits no one’s talking about, visceral fat reduction, neuroprotection, and dopamine rewiring, and why those only matter if you’re treating the drug as a catalyst, not a crutch. If you’re using GLP-1s and not building real habits, you’re just renting results. This episode will show you how to make them work with your training, not instead of it.    Listen up, this one’s essential.   I Also Discuss:   (00:01) Ozempic Isn’t Magic—It’s Metabolic Warfare (03:38) Why GLP-1s Won’t Save You If You Don’t Train (05:07) The Muscle Mass Trap No One Warns You About (11:20) How GLP-1s Trick You Into Skipping the Work (17:09) The Price You’ll Pay If You Don’t Plan Life After the Drug   Thank You For our Sponsors:   NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/    Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin  2 Shred: https://www.unmatchedsupps.com/products/2shred  

Are you stuck at a fat loss plateau despite perfect diet and training? In this episode of the Kris Gethin Podcast, I break down the peptide protocols that changed everything - no fluff, just the compounds that actually work for stubborn fat, metabolic plateaus, and body recomposition. I've been using peptides since 2017, starting with the Wolverine stack for injury recovery. Now I'm getting flooded with questions about fat-burning peptides, and rightfully so - these compounds are showing serious promise when used correctly. You'll learn the mechanisms behind AOD9604, 5-amino-1-MQ, SLUPP332, tesamorelin, ipamorelin, tesofensine, and CJC-1295. I explain how these peptides increase lipolysis, prevent fat storage, suppress appetite, and enhance insulin sensitivity. Listen in for the clinical evidence, safety protocols, blood work requirements, and why these aren't magic bullets. Let’s get into it.   I Also Discuss: (00:41) My First Peptide Stack and Why I Started Using Them  (02:58) What Peptides Are and Why They're So Powerful for Fat Loss (05:24) AOD9604: The Pure Fat Loss Agent That Targets Only Adipose Tissue  (07:19) 5-Amino-1-MQ: The Game Changer for Metabolic Plateaus  (09:42) SLUPP332: The Exercise Mimetic That Browns Your Fat  (11:42) Tesamorelin: The Visceral Fat Assassin for Dangerous Belly Fat  (13:06) Ipamorelin: Precision GH Catalyst for Muscle Preservation  (14:36) Tesofensin: The Appetite Annihilator for Cravings and Binge Eating  (15:44) CJC-1295: Enhanced Lipolysis and Metabolic Rate Boost  (18:18) Critical Safety Protocols and Blood Work Requirements   Thank you to our sponsors: NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris  BiOptimizers - code KRIS10 for 10% off  https://bioptimizers.com/    Find more from Kris: Website: https://www.krisgethin.com/  Instagram: https://www.instagram.com/krisgethin/  Youtube: https://www.youtube.com/krisgethin