
Two Doctors: How to Heal Your Gut, Boost Your Energy & Feel Amazing After 40 with Dr. Josh Axe and Dr. Will Cole
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You’re doing the things. You bought the probiotic, you’re eating cleaner, you’re trying to sleep. And somehow your energy still isn’t where you want it. In Part 2 of this conversation, Dr. Josh Axe and Dr. Will Cole go deeper into gut health, cellular energy, and the surprising truth that how you feel isn’t only about what you eat. It’s also about what you carry. This one is about healing that actually lasts and learning how to hold onto your energy for the long haul.
What You'll Learn in This Episode:
- Why a GI Map test tells you more about your gut health than guessing at a probiotic off the shelf
- How probiotics actually work (hint: most of them don't move in and stay), and what to eat to feed the good bacteria
- The reason probiotics can nearly double your B-vitamin absorption, so a spoon of sauerkraut can beat a multivitamin
- How your mitochondria and your microbiome talk to each other, and what happens to your energy when that line gets scrambled
- Why loneliness, shame, and old trauma show up in your cells even though no lab can measure them
- What the ACE score reveals about the link between childhood experiences and adult inflammation, hormones, and burnout
- The both/and approach to healing that treats your body, mind, and spirit as one system God designed
- What Dr. Josh Axe and Dr. Will Cole actually recommend for stubborn tendon pain, plus why rest and Sabbath are part of the plan
Timestamps:
(00:51) — The probiotic myth, and why a GI Map matters before you supplement
(02:14) — Your bowel movements as a daily window into gut health
(02:35) — How probiotics really work: transient, but they change the environment
(03:12) — Feeding the good bacteria with soluble fiber, polyphenols, and fermented foods
(04:31) — Why probiotics can double your B-vitamin absorption
(05:18) — Supporting the gut lining with zinc and L-glutamine, plus glutamine for immunity
(07:20) — Dr. Will Cole on slow GI motility and what "normal" really means
(08:39) — Mitochondria, the microbiome, and the crosstalk that drives your energy
(09:50) — The full life cycle of the biome: pre, pro, para, and postbiotics
(10:59) — Why you can't supplement your way out of a poor diet
(12:16) — How loneliness and lack of purpose show up in a single cell
(13:47) — The ACE score: childhood experiences and adult disease
(15:27) — The communication theory of aging and the scratched-record analogy
(17:14) — Dr. Josh Axe on his mom's cancer and the emotional, spiritual side of healing
(18:56) — Confession as the ultimate detoxification
(19:43) — Alli's tennis elbow: PRP, BPC-157, and the peptide stack
(23:28) — Don't underestimate rest and Sabbath for recovery
(24:10) — Lightning round: what to put in your cart for mitochondria and energy
Links to great things we discussed:
- Heal Your Cells
- Function Health
- Uplift App
- Join me on Substack: Wise Woman Method
- Alli on YouTube
I hope you loved this episode! 🎉If you haven’t already, make sure you tap that subscribe button on Apple Podcasts or Spotify so you never miss an episode. And guess what? We're on YouTube now too! If the show has been a bright spot for you, leaving a review or a few stars is such a gift. It truly means the world to me.
Take good care of yourself, and keep showing up with joy. Share this episode with a friend who might enjoy it too!
xo,
Alli
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