December 2025 CHEST Journal Editor Highlights

CHEST December 2025, Volume 168, Issue 6       CHEST® journal's Editor in Chief Peter Mazzone, MD, MPH, FCCP, highlights key research published in the journal CHEST December 2025 issue, including an exploration of the relationship between inflammation and mucociliary clearance in chronic respiratory conditions, an investigation into the association of hypoxic burden with major cardiovascular events, and more.       Moderator:    Peter Mazzone, MD, MPH, FCCP

Gina M. Piscitello, MD, and Katrina E. Hauschildt, PhD, BCPA, join CHEST® Journal Podcast Moderator Gretchen Winter, MD, to discuss their research into the ways that and extent to which hospital policies influence clinician approaches to decisions to withhold or withdraw life-sustaining treatment among patients admitted to an ICU.  DOI: 10.1016/j.chest.2025.06.036 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers’ opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Kristen R. Mathias, MD, MHS, joins CHEST® Journal Podcast Moderator Gretchen Winter, MD, to discuss her research into the ways patients with sarcoidosis describe their experiences with the disease, how they are impacted by uncertainty around sarcoidosis management, and the challenges they face in receiving care.   DOI: 10.1016/j.chest.2025.06.025 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers’ opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Eva-Maria Schmolke, MD, and Kathrin Knochel, MD, join CHEST® Journal Podcast Moderator Matt Siuba, DO, MS, to discuss their research into the institutional implementation of a national triage guideline in German ICUs during the initial phases of the COVID-19 pandemic and their subsequent analysis of widespread covert triage as a response to legal uncertainty around triage guidelines.   DOI: 10.1016/j.chest.2025.05.044 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers’ opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

CHEST November 2025, Volume 168, Issue 5  CHEST® journal's Editor in Chief Peter Mazzone, MD, MPH, FCCP, highlights key research published in the journal CHEST November 2025 issue, including an investigation into oxygen saturation targets and neurologic outcomes after cardiac arrest, an exploration of the association of shared decision-making with long-term adherence to lung cancer screening, and more.    Moderator:    Peter Mazzone, MD, MPH, FCCP

Katarina Zeder, MD, PhD, joins CHEST® Journal Podcast Moderator Matt Siuba, DO, MS, to discuss her research into the ways in which longitudinal pulmonary arterial pressure trajectories inform clinical outcome in patients undergoing kidney transplantation.  DOI: 10.1016/j.chest.2025.05.024 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers’ opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Shaurya Taran, MD, joins CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss his research into the association between low-tidal-volume ventilation and mortality in patients with acute brain injuries receiving mechanical ventilation.   DOI: 10.1016/j.chest.2025.06.042 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers’ opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

Stephanie C. DeMasi, MD, joins CHEST® Journal Podcast Moderator, Matt Siuba, DO, MS, to discuss her research comparing neurologic outcomes between lower and higher oxygen saturation targets following cardiac arrest.  DOI: 10.1016/j.chest.2025.04.027 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers’ opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine. 

CHEST October 2025, Volume 168, Issue 4  CHEST® journal's Editor in Chief Peter Mazzone, MD, MPH, FCCP, highlights key research published in the journal CHEST October 2025 issue, including an exploration of the association of physical frailty with incidence and life expectancy of COPD, an investigation of the health and utilization burden of OSA among US active-duty military personnel, and more.     Moderator:    Peter Mazzone, MD, MPH, FCCP

Stephan von Düring, MD, and Eddy Fan, MD, PhD, join CHEST® Journal Podcast Moderator Matt Siuba, DO, MS, to discuss their research into the association between mechanical power within the first 24 hours and ICU mortality in adult patients with acute hypoxemic respiratory failure who are mechanically ventilated.  DOI: 10.1016/j.chest.2025.03.012 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers’ opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.