Is ADT Needed During Prostate Radiation? with Dr. Nima Aghdam

AI has existed for decades, but modern deep learning is finally delivering precision decisions in clinic. Dr. Spratt details how ArteraAI’s predictive biomarker—validated on long-term randomized data—can spare roughly two-thirds of eligible men from ADT without compromising outcomes. We unpack ADT’s quality-of-life trade-offs, practical training and nutrition strategies to preserve muscle, and where AI is headed next (post-surgery models, higher-risk disease). You’ll also hear a clear framework for shared decision-making so men are treated as people, not just numbers.Key Points✅ AI meets prostate cancer. ArteraAI, developed by Dr. Daniel Spratt’s team, is now part of the NCCN guidelines—helping doctors know which patients truly benefit from hormone therapy.✅ Two-thirds can skip ADT. Long-term data from the RTOG 9408 trial show most men can avoid the side effects of hormone therapy without affecting outcomes.✅ Quality of life first. Treatments should improve survival or well-being—if they don’t, they shouldn’t be used.✅ Lifestyle still matters. Exercise, protein, and resistance training help men on ADT preserve muscle and energy.✅ The future is personalized. New AI models will soon guide therapy for higher-risk patients and integrate full-body health data for truly tailored care.⏱️ Time-Stamped Highlights00:00 – Why AI in prostate cancer now? From buzzword to bedside with ArteraAI.01:30 – Deep learning vs. “human-defined” inputs; beyond Gleason to hundreds of slide features.03:10 – Landmark validation: RTOG 9408 and how the model predicts who benefits from ADT.05:00 – ADT trade-offs: longevity vs. libido, energy, bone/muscle; treat only if it improves life or survival.07:15 – “Exercise is medicine”: the 10-minute rule, protein targets, and resistance training on ADT.09:00 – Current indication: primarily intermediate-risk (Gleason 7) men receiving radiation.10:45 – What’s next: models for higher-risk and post-prostatectomy patients; shorter-course ADT questions.13:00 – “Black box” & explainability: why robust external validation matters for trust.15:10 – Access & coverage: ordering via online portal; CMS coverage; what patients can ask their doctors.17:20 – Shared decision-making: reduce PSA anxiety; treat the person, not the number.___________________________________🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular renewal, metabolic health, and fat loss. Special offer for our listeners: Get the ProLon kit for $148 → https://bit.ly/3TVehAxAG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop. Supports gut health, immunity, energy, and focus. Try it here → https://bit.ly/3mA2tVV___________________________________💪 Exclusive MembershipWant deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. →...

Can high-precision radiation change how we treat metastatic prostate cancer? In this episode, I’m joined by Ronald C. Chen, MD, MPH—radiation oncologist, national guideline author (AUA/ASCO), and clinical-trial leader with 170+ publications—to unpack stereotactic body radiation therapy (SBRT) for disease that has spread to lymph nodes, bones, and beyond. We get practical about who benefits, where SBRT shines, and how to balance treatment intensity with quality of life.SBRT offers highly focused, short-course radiation that can control limited (“oligo-”) metastatic prostate cancer and delay systemic therapy for many men. Dr. Chen explains when to treat individual nodes/bone lesions versus comprehensive nodal fields, how anatomy determines dose/fraction choices (often 3–5 treatments), and why modern SBRT sometimes reduces the need for concurrent hormone therapy. We cover salvage options after prior radiation (brachytherapy seeds, HIFU, cryo, repeat SBRT, or salvage prostatectomy), the role and limits of PSMA PET, fracture risk and bone health (DEXA), and the evolving data—including the large NRG-GU013 trial—for higher-risk disease. Throughout, we emphasize shared decision-making, realistic expectations, and considering clinical trials when data are evolving.00:00 – Can SBRT change metastatic prostate cancer care? Meet Dr. Ron Chen.01:00 – Disclaimer: Views are Dr. Geo’s and guests’—independent of NYU Langone.07:00 – Recurrence scenarios: prostate-only, nodal, or bone/other; why catching early matters.12:00 – Five salvage options after prostate radiation: seeds (brachytherapy), HIFU, cryo, SBRT (focal or whole-gland), or salvage prostatectomy.19:00 – Nodal relapse: treat all pelvic nodes + ADT ± abiraterone vs. SBRT to a few nodes only—how patient priorities drive the plan.26:30 – Oligometastasis: SBRT alone can control disease for many men ~2+ years on average, delaying hormones.30:00 – Fractions: why 3–5 treatments is typical and how adjacent bowel/organ anatomy sets the pace.31:00 – SBRT in 2 fractions for select primary cases looks promising; high-risk SBRT under study (NRG-GU013).37:00 – Bone mets: SBRT preferred; understanding fracture risk (tumor size, dose, shrinkage).40:00 – DEXA before ADT; spine SBRT can spare the spinal cord with modern planning.48:00 – Clavicle/hilar nodes: SBRT near lung/heart/esophagus—safe with careful dose constraints.56:00 – Why clinical trials matter for “how long on hormones?” and other open questions.57:00 – Soft-tissue mets (liver/brain): SBRT can help, often alongside systemic therapy.59:00 – Parting advice: early detection, close follow-up, and hopeful trajectory of care.___________________________________🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular renewal, metabolic health, and fat loss. Special offer for our listeners: Get the ProLon kit for $148 → https://bit.ly/3TVehAxAG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop. Supports gut health, immunity, energy, and...

Is androgen deprivation therapy (ADT) always necessary when prostate cancer patients undergo radiation? And if so, for how long—six months, a year, two years? In this insightful conversation, Dr. Geo sits down with Dr. Nima Aghdam, radiation oncologist at NY CyberKnife and NYU Langone, to explore the evolving role of ADT in prostate cancer treatment.Dr. Aghdam shares his expertise on advanced radiation techniques like SBRT, personalized approaches to ADT duration, and the importance of lifestyle interventions. Together, they highlight how individualized care can improve survival, minimize side effects, and help men thrive beyond diagnosis.If you or a loved one are facing decisions about radiation and hormone therapy for prostate cancer, this episode offers clarity, evidence-based guidance, and hope.Radiation vs. Surgery: Both are highly effective; choice often comes down to quality-of-life goals and patient preference.Lymph Node Positive Disease: Options include focal SBRT or comprehensive external beam therapy; treatment decisions must balance efficacy and quality of life.Lifestyle’s Role: Exercise and nutrition create a “hostile microenvironment” for cancer, improving both survival and side-effect management.Radiation Innovations: From rectal spacers to fewer treatment sessions (trials reducing SBRT from five to two fractions), techniques continue to evolve.ADT Considerations:Historically prescribed for up to 24–36 months with radiation.New genomic and AI-based classifiers may allow some men to stop ADT earlier (6–12 months).Balancing survival benefits with quality of life is critical.PSA Anxiety: PSA fluctuations don’t always equate to recurrence or mortality. Context and long-term monitoring matter more than isolated numbers.Finding the Right Oncologist: Beyond equipment and technology, trust and honest communication with your doctor are essential.Timestamps00:00 – Introduction: Is ADT always necessary during radiation?05:00 – Radiation vs. surgery for localized and advanced prostate cancer.10:00 – Salvage options: what happens if radiation or surgery fails?13:00 – Treating prostate cancer with lymph node involvement.17:00 – Communicating metastasis risk and long-term outcomes to patients.18:30 – Lifestyle interventions as part of prostate cancer care.21:00 – Rectal spacers and preparation for SBRT.23:30 – Advances in SBRT: reducing from five fractions to two.25:30 – Understanding fractions, dosage, and radiation delivery.32:00 – Personalizing ADT: who benefits, and for how long?36:00 – Clinical trials on ADT duration (6, 12, 18, 24+ months).39:00 – Radiation’s long-lasting effects and how ADT fits in.42:00 – PSA recurrence vs. actual risk of mortality45:00 – Patient anxiety and the psychological impact of PSA testing.47:00 – Exercise and lifestyle: evidence for improved survival.49:00 – Supplements, PSA manipulation, and misinformation.51:00 – How to choose a reputable radiation oncologist.56:00 – Evolving evidence: are radiation-related risks lower today?58:00 – Parting words: seeing prostate cancer as a chance for transformation.___________________________________🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular...

What if prostate cancer surgery meant fewer incisions, faster recovery, and more precise cancer control? Today I’m joined by Dr. Michael D. Stifelman, Chair of Urology at Hackensack University Medical Center and a pioneer in robotic surgery with 4,000+ robotic procedures. We unpack how single-port robotics, real-time margin assessment, and AI are reshaping outcomes—while protecting continence and erections.Dr. Stifelman traces robotics from the early-2000s “pioneer phase” (and heavy skepticism) to today’s standard of care, explaining why reproducibility, visualization, and tissue-sparing dexterity made the difference. We compare surgery vs. radiation (and focal therapies), when each shines, and why sequencing often matters—especially in higher-risk disease. He shares emerging tech like single-port prostatectomy, intra-operative margin evaluation (e.g., Histo-style scanning), quantitative surgical analytics, and even remote robotic assistance. We also talk “trifecta” outcomes, the role of genomics in Gleason 7 decision-making, and why lifestyle medicine and optimizing the tumor micro-environment go hand-in-hand with any treatment.Time-Stamped Highlights00:00 – Why fewer incisions + faster recovery are now real in prostate surgery05:40 – Work–life changes that improved health (sleep, exercise, biking)09:10 – Open vs. robotic: why reproducibility (teachability) matters11:05 – Robotics adoption curve: from early resistance to mainstream19:05 – Outcomes today: continence and erections after modern surgery20:10 – “Yes, I’m a surgeon—and here’s my bias.” Radical honesty with patients22:05 – Offering the full menu: surveillance, focal (HIFU/cryotherapy), surgery, SBRT, proton25:40 – High-risk (Gleason 8–9): why surgery-first can preserve options & avoid long ADT34:00 – Dexterity & visualization: why robots spare nerves with less trauma35:10 – Real-time margin assessment during surgery to reduce positives40:00 – The “trifecta” (cancer control, continence, erections) and patient priorities42:10 – Genomics to risk-stratify Gleason 7 and guide surveillance vs. treatment45:00 – Future: nerve activation mapping & fluorescence to “light up” cancer46:10 – Single-port prostatectomy: smaller access, faster return of function (select patients)49:00 – Quantifying surgery with analytics; tele-mentoring & remote console potential52:30 – How to find Dr. Stifelman & closing advice___________________________________🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular renewal, metabolic health, and fat loss. Special offer for our listeners: Get the ProLon kit for $148 → https://bit.ly/3TVehAxAG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop. Supports gut health, immunity, energy, and focus. Try it here → https://bit.ly/3mA2tVV___________________________________💪 Exclusive MembershipWant deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership___________________________________📌 Follow and Connect📺 YouTube → Dr. Geo Prostate Podcast — https://www.youtube.com/@DrGeoProstatePodcast🎧 All Episodes → Captivate.fm Archive — https://dr-geo-prostate-podcast.captivate.fm📸 Instagram → https://bit.ly/DRGEO-INSTA-YT📘 Facebook → https://bit.ly/POD-FB-DrGeo💼 LinkedIn → https://bit.ly/DRGEO-LINKEDIN-YT🛒 Supplements → XY Wellness https://bit.ly/3uJPC7Z | Mr. Happy https://bit.ly/3TE7tWE🌐 DrGeo.com Website → https://bit.ly/43khht0___________________________________📣 Hashtags#DrGeoProstatePodcast #ProstateHealth #ProstateCancer...

What if prostate cancer treatment weren’t months of daily radiation—but five ultra-precise sessions guided in real time by MRI? Today, Dr. Michael J. Zelefsky (Professor of Radiation Oncology, NYU Grossman School of Medicine) explains how MRI-LINAC and adaptive planning are redefining accuracy, reducing side effects, and personalizing care. A pioneer behind IMRT and image-guided radiotherapy, Dr. Zelefsky breaks down SBRT vs. IMRT, protons vs. photons, HDR brachytherapy, when to add hormone therapy, and how genomics + AI are shaping what’s next.In this conversation, Dr. Zelefsky charts the evolution from long-course radiation to short-course SBRT with outcomes comparable to 7–9 week regimens—thanks to precision imaging and planning. He clarifies where IMRT ends and SBRT begins, why protons haven’t shown superiority over photons in prostate cancer, and where HDR brachytherapy (Ir-192) shines—especially as a boost in higher-risk disease. We dig into dose equivalence (why 5×8 Gy can match ~80–90 Gy long-course), risk-based treatment + ADT duration, and how Decipher/Artera scores can refine decisions. Most exciting: MRI-LINAC with continuous motion monitoring keeps the prostate in a virtual “bullseye,” enabling whole-gland treatment with focal boosts today—and potentially true focal therapy tomorrow as biologic imaging and AI mature.Time-Stamped Highlights00:00 – Welcome 02:00 – Why Dr. Zelefsky’s work is so respected; career arc and impact04:00 – What changed: CT/MRI planning → 3D-CRT → IMRT → SBRT12:45 – IMRT vs. SBRT: definitions, session counts, who gets what19:10 – Energy sources overview: photons, protons, brachytherapy20:30 – Protons vs. photons: evidence, indications, cost, access24:00 – HDR brachytherapy (Ir-192) as a temporary “in-and-out” boost28:00 – Dose logic: why 5×8 Gy (~40 Gy) ≈ long-course 80–90 Gy29:30 – Risk groups (low/intermediate/high) and when ADT is crucial33:00 – ADT durations (6–36 months): what trials actually showed37:00 – Genomics (Decipher/Artera): resolving risk discrepancies39:00 – What MRI-LINAC adds: real-time adaptive planning43:00 – Continuous Motion Monitoring (CMM): beam stops if target moves47:00 – Treat whole gland + boost the DIL (FLAME study approach)49:00 – Toward focal therapy with better biologic imaging + AI54:00 – How to choose: values, side-effects, lifestyle, comorbidities01:01:00 – Final guidance: don’t be overwhelmed—multiple good option🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular renewal, metabolic health, and fat loss. Special offer for our listeners: Get the ProLon kit for $148 → https://bit.ly/3TVehAxAG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop. Supports gut health, immunity, energy, and focus. Try it here → https://bit.ly/3mA2tVV💪 Exclusive MembershipWant deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → <a...

HIFU (high-intensity focused ultrasound) is one of the most talked-about focal therapies in prostate cancer—but who is it really right for? In this conversation, Dr. Matthew Cooperberg (UCSF)—a leading voice in urology, epidemiology, and integrative prostate cancer care—breaks down patient selection vs. energy modality, how modern imaging (MRI, fusion, RSI) drives precision, what genomics (e.g., Decipher) can and can’t tell us, and how salvage options compare after focal therapy vs. radiation. We also tackle lifestyle factors, trial design, and why midlife PSA screening (ideally &lt;1 between ages 45–55) remains crucial. 👉 View more at DrGeo.com00:00 – Welcome + episode setup (HIFU overview, aims of focal therapy) 04:10 – The real first question: Who is a candidate? (selection &gt; modality) 05:10 – What “focal therapy” means (lesion-only, margin, hemi-ablation) + imaging progress 06:25 – Recurrence after focal therapy: targeting, dose, or biology? Follow-up biopsies 07:40 – Genomics (Decipher): predicting recurrence; how results change counseling 09:30 – Lifestyle &amp; microenvironment: can diet/exercise influence outcomes? 11:00 – Salvage after focal vs. radiation: fibrosis, feasibility, quality of life 14:00 – Cryotherapy vs. HIFU: image guidance, control, and why HIFU advanced 16:00 – Imaging upgrades (MRI fusion, RSI, C-13 spectroscopy) and treatment constraints 17:00 – IRE (irreversible electroporation): role for apical tumors, early results 18:00 – TULSA, water/thermal concepts, focal radiation, partial prostatectomy: what’s known 20:00 – Smarter trials: active surveillance ± focal therapy for borderline cases 22:00 – The counseling hierarchy: decision first, technology second 24:30 – Proton vs. photon incentives; why advertising confuses choices 26:30 – UCSF’s program: mostly HIFU; where IRE fits; adding new machines prudently 28:30 – The real bottleneck: sub-millimeter targeting; AI-guided ablation future 33:00 – HIFU mechanics: probe size, apex/anterior reach, distance constraints 35:00 – “I want HIFU for Gleason 8”: agency, nuance, and when we advise against it 38:00 – A cautionary case: negative biopsy → later mets—what it teaches us 40:30 – Millennials, risk tolerance, and why PSA at 45–55 (&lt;1 is ideal) matters 44:00 – Growth vs. spread: which high-grade tumors can we treat focally? 46:00 – How low vs. high genomic scores tilt decisions (and their limits) 47:30 – Where to find Dr. Cooperberg + parting PSA advice___________________________________🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular renewal, metabolic health, and fat loss. Special offer for our listeners: Get the ProLon kit for $148 → https://bit.ly/3TVehAxAG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop. Supports gut health, immunity, energy, and focus. Try it here → https://bit.ly/3mA2tVV___________________________________💪 Exclusive MembershipWant deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. →<a href="https://drgeo.com/membership?utm_source=chatgpt.com" rel="noopener...

Can high-dose IV Vitamin C really support cancer treatment—even in men with prostate cancer? In this episode of the Dr. Geo Prostate Podcast, Dr. Geo welcomes Dr. Paul Anderson, one of the world’s leading voices in integrative oncology with 30+ years of clinical experience and NIH-funded cancer research.Together, they unpack how vitamin C works differently when taken orally versus intravenously, what the latest research shows about IV vitamin C, and how it may impact the tumor microenvironment and immune response.Listeners will also learn about practical approaches to integrative oncology, the role of detoxification and immune health, and what patients with advanced prostate cancer should know before seeking out IV vitamin C therapy.✅ What You’ll Learn in This Episode:How oral vs. IV vitamin C behave differently in the bodyWhat the latest science says about IV vitamin C in cancer careWhy the tumor microenvironment matters for long-term outcomesHow IV vitamin C may support men with advanced prostate cancerSynergies with lifestyle therapies, immunotherapy, and sauna💡 Don’t forget to subscribe, rate, and review the podcast! Every review helps us reach more men who want to thrive, not just survive._________________________ 🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular renewal, metabolic health, and fat loss. Special offer for our listeners: Get the ProLon kit for $148 → https://bit.ly/3TVehAxAG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop. Supports gut health, immunity, energy, and focus. Try it here → https://bit.ly/3mA2tVV💪 Exclusive MembershipWant deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and member perks. → https://drgeo.com/membership📌 Follow and Connect📺 YouTube → Dr. Geo Prostate Podcast / @drgeoprostatepodcast🎧 Listen to All Episodes → https://dr-geo-prostate-podcast.captivate.fm/_________________________ ⚠️ Disclaimer: This podcast is educational and not medical advice. Always consult your healthcare provider before making changes to your treatment.

In this inspiring episode of the Dr. Geo Prostate Podcast, Dr. Geo sits down with Dr. Amy Rothenberg — a licensed naturopathic doctor for over 36 years, 2017 Physician of the Year by the American Association of Naturopathic Physicians, and a living example of resilience.After 18 rounds of chemotherapy in 2014, Dr. Rothenberg competed in her first triathlon just six months later. She shares her journey of overcoming breast, ovarian, and leukemia diagnoses while integrating both conventional and naturopathic medicine. Her best-selling book, You Finished Treatment, Now What?, offers cancer survivors a compassionate, practical roadmap to reclaim their health.Whether you’re living with cancer, supporting someone who is, or looking for ways to live better with age, this conversation is filled with actionable insights on healing, prevention, and thriving.Key Points:A Doctor Becomes the Patient – How Dr. Rothenberg faced multiple cancer diagnoses and treatments while maintaining her health philosophy.Integrative Approach – Combining conventional oncology care with naturopathic strategies for side effect management, immune support, and recovery.The Role of Movement – How exercise, even in small amounts, supports treatment efficacy and recovery.Fasting Mimicking Diet &amp; Microbiome Support – Evidence-backed dietary strategies during treatment and beyond.Mindset &amp; Resilience – The importance of goal-setting, community support, and finding joy during and after cancer care.Life After Treatment – Practical steps to reduce recurrence risk and improve quality of life.Resources &amp; Links Mentioned:Book: You Finished Treatment, Now What? – Order here or at your local bookstore.Learn more about Dr. Amy Rothenberg: dramyrothenberg.comFind a licensed naturopathic doctor: naturopathic.orgOncology Association of Naturopathic Physicians: oncanp.org----------------🌱 Partner OffersProLon 5-Day Fasting Mimicking Diet — Enjoy fasting benefits with food. Supports cellular renewal, metabolic health, and fat loss. Special offer for our listeners: Get the ProLon kit for $148 here → https://bit.ly/3TVehAxAG1 by Athletic Greens — 75 high-quality vitamins, minerals, probiotics, and adaptogens in one daily scoop to support your gut, immunity, energy, and focus. Try it here → https://bit.ly/3mA2tVV💪 Exclusive MembershipWant deeper insights? Join The Dr. Geo Prostate Podcast Exclusive Membership for curated transcripts, detailed show notes, expert resources, and exclusive member perks. Join here https://drgeo.com/membership📌 Follow and Connect📺 YouTube → Dr. Geo Prostate Podcast / @drgeoprostatepodcast 🎧 Listen to All Episodes → Dr. Geo Podcast https://dr-geo-prostate-podcast.capti...Shop Dr. Geo’s formulated supplements → XY Wellness https://bit.ly/3uJPC7Z → Mr. Happy https://bit.ly/43YSDiq📸 Instagram → https://bit.ly/DRGEO-INSTA-YT📘 Facebook → https://bit.ly/POD-FB-DrGeo💼 LinkedIn →https://bit.ly/DRGEO-LINKEDIN-YT🌐 Website → https://bit.ly/43khht0#CancerSurvivor #CancerRecovery #IntegrativeMedicine #NaturopathicMedicine #CancerSupport #ProstateHealth #ThrivingAfterCancer #CancerTreatment #Survivorship #CancerWellness #MensHealth #ProstateCancer #HealthTips #OncologySupport #wellnessjourney ⚠️ DisclaimerDISCLAIMER: This audio is educational and not medical advice. The views expressed are my own and not those of my employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for...

Are low testosterone clinics helping men—or creating more harm than good?In this revealing episode, Dr. Geo is joined by Dr. Justin Dubin, a leading urologist and host of The Man Up Podcast, to pull back the curtain on the booming world of direct-to-consumer testosterone clinics.Together, they explore:The truth behind the rise of low-T clinicsWhat these businesses get right—and where they dangerously fall shortDr. Dubin’s undercover study: 6 out of 7 clinics offered testosterone to men who didn’t qualifyThe overlooked risks of infertility, heart issues, and priapismHow buzzwords like “optimization” may be misleading patientsWhat every man should ask before starting testosterone therapyIf you’ve been curious about TRT, overwhelmed by online advice, or simply want to make informed decisions about your hormonal health—this episode is for you.💡 If you're facing prostate cancer surgery, concerned about erectile function, or simply fascinated by medical innovation, this episode is a must-listen.👉 Learn more about Kyzatrex at KYZATREX.com/testing-kit. 💡 Don’t forget to subscribe, rate, and leave a review! Each review helps us reach more men who want to thrive, not just survive._________________________&nbsp;Thank you to our July 2025 SponsorKYZATREX is an FDA-approved oral testosterone replacement therapy that helps restore testosterone levels back to normal. It’s not an injection or a messy gel — just a simple twice-daily pill that fits easily into your routine. Find out where you stand. Order a testing kit today at KYZATREX.com/testing-kit. Call your doctor to learn more about KYZATREX. For more information, visit www.kyzatrex.com or call 1-833-949-5040.👉 Ask your doctor about Kyzatrex or visit KYZATREX.com/testing-kit. [https://bit.ly/4lUgY0j] to learn more._________________________&nbsp;The ProLon 5-Day Fasting Mimicking Diet is a plant-based meal program designed to provide fasting benefits while allowing food intake. Developed by Dr. Valter Longo, it supports cellular renewal, fat loss, and metabolic health through low-calorie, pre-packaged meals that keep the body in a fasting state.Special Offer: As a listener, you can get the ProLon kit for just $148 using this [https://bit.ly/3TVehAx ].We’d also like to thank our partner AG1 by Athletic Greens. AG1 includes 75 high-quality vitamins, minerals, whole-food sourced ingredients, probiotics, and adaptogens to help you start your day right. This blend supports your gut, immune system, energy, focus, and more—all in one daily scoop.&nbsp;<a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbFBTS2pPaFp6RXlFZ3ptcXNJVTN3eXBQR1JNZ3xBQ3Jtc0tudTY1VndoTE9Bdk5FUEM4QjR1ZUIzVzZaem1yclk0OFVjSHBJcjdjLWU0N1NQaHRnV1ZLSkxHMFRWT21GZXBBTUJNSHhWQzNranpQdzVQdU1wZDE0bE9nU3RMNFg5cjFjM184LXJ6X3EwWEFMbUU0cw&amp;q=https%3A%2F%2Fbit.ly%2F3mA2tVV&amp;v=HMxxUOlUJ_s" rel="noopener noreferrer"...

In this episode of the Dr. Geo Prostate Podcast, Dr. Geo welcomes Dr. Mohit Khera, a globally recognized leader in men’s health, Professor of Urology and Director of the Executive Health Program at Baylor College of Medicine. With over 160 peer-reviewed publications and decades of clinical experience in testosterone therapy, male infertility, and prostate health, Dr. Khera shares cutting-edge insights on testosterone replacement therapy (TRT), including the rise of oral testosterone like Kyzatrex, and the evolving understanding of testosterone’s relationship to prostate cancer.Whether you’re considering TRT, recovering from prostate cancer, or supporting a loved one’s health journey, this conversation brings clarity to one of men’s most pressing health topics.What You’ll Learn:The 4 C’s framework to determine the best TRT option:Cost, Compliance, Convenience, ConcentrationWhy oral testosterone (Kyzatrex, Tlando, Jatenzo) is gaining traction—and what makes them differentHow Kyzatrex may help preserve fertility by reducing gonadotropin suppressionWhat the TRAVERSE trial revealed about TRT and cardiovascular safetyWhy low testosterone may be linked to more aggressive prostate cancerWhat the latest science says about BAT (Bipolar Androgen Therapy) for advanced prostate cancerThe truth about testosterone’s impact on BPH and urinary symptomsWhy total testosterone isn't enough—labs like SHBG, DHT, estradiol, and free testosterone matterKey Insights:TRT doesn’t cause prostate cancer — and may even have protective effects in some men.Testosterone is the best barometer of male health—predicting cardiovascular risk, mood, bone density, and more.BAT (Bipolar Androgen Therapy) is showing promise in treating advanced prostate cancer in specific scenarios.Avoid unnecessary aromatase inhibitors and DHT blockers unless clinically indicated.💡 If you're facing prostate cancer surgery, concerned about erectile function, or simply fascinated by medical innovation, this episode is a must-listen.👉 Learn more about Kyzatrex at KYZATREX.com/testing-kit. 💡 Don’t forget to subscribe, rate, and leave a review! Each review helps us reach more men who want to thrive, not just survive._________________________&nbsp;Thank you to our July 2025 SponsorKYZATREX is an FDA-approved oral testosterone replacement therapy that helps restore testosterone levels back to normal. It’s not an injection or a messy gel — just a simple twice-daily pill that fits easily into your routine. Find out where you stand. Order a testing kit today at KYZATREX.com/testing-kit. Call your doctor to learn more about KYZATREX. For more information, visit www.kyzatrex.com or call 1-833-949-5040.👉 Ask your doctor about Kyzatrex or visit KYZATREX.com/testing-kit. [https://bit.ly/4lUgY0j] to learn...