This EndoLife podcast

How the Low FODMAP Diet Helps You Manage Histamine Intolerance/Mast Cell Activation Syndrome

01/08/2025
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Today I wanted to talk about the low FOMDAP diet, but not for the reasons you may think.

Today, I don’t actually want to talk about it specifically for IBS/SIBO (though we will touch upon that again), I want to talk about its benefits for histamine, because the low FODMAP diet can actually be a way to lower histamine levels.


Show notes

Low FODMAP diet info

https://www.monashfodmap.com/about-fodmap-and-ibs/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4918736/


Endometriosis and histamine/MCAS

https://pubmed.ncbi.nlm.nih.gov/22332753/

https://www.emjreviews.com/reproductive-health/article/targeting-mast-cells-as-a-viable-therapeutic-option-in-endometriosis/

https://pubmed.ncbi.nlm.nih.gov/31998139/

https://www.eds.clinic/articles/the-role-of-mast-cells-in-endometriosis

https://www.gynecologiconcologyinstitute.org/news/endometriosis/endometriosis-news/mast-cell-activation-syndrome-and-endometriosis-a-potential-link-for-unexplained-symptoms-in-women/


MCAS

https://www.degruyterbrill.com/document/doi/10.1515/dx-2020-0005/html

https://pubmed.ncbi.nlm.nih.gov/28780942/

https://med.virginia.edu/ginutrition/wp-content/uploads/sites/199/2020/06/Mast-Cell-Activation-Syndrome-June-2020.pdf


MCAS and comorbidities

https://pubmed.ncbi.nlm.nih.gov/33980338/

https://pubmed.ncbi.nlm.nih.gov/32803794/

https://pubmed.ncbi.nlm.nih.gov/32434316/

https://pubmed.ncbi.nlm.nih.gov/31267471/

https://www.eds.clinic/articles/the-role-of-mast-cells-in-endometriosis

https://www.potsuk.org/about-pots/associated-conditions/hypermobility-and-pots/

https://www.siboinfo.com/associated-diseases.html - various studies highlighting SIBO links to all conditions listed in the episode

https://pubmed.ncbi.nlm.nih.gov/29326369/


Podcast episodes on POTS/EDS/SIBO/IC/MCAS

https://www.theendobellycoach.com/podcast/endometriosis-sibo-ic-and-allergies-the-histamine-connection?rq=histamine

https://www.theendobellycoach.com/podcast/endo-ehlers-danlos-syndrome-connection?rq=POTS

https://www.theendobellycoach.com/podcast/endo-and-adhd?rq=POTS

https://www.theendobellycoach.com/podcast/strategies-for-lowering-histamine-reducing-allergies-endometriosis?rq=histamine

https://www.theendobellycoach.com/podcast/low-oxalate-low-histamine-elimination-diet-interstital-cystitis?rq=histamine

https://www.theendobellycoach.com/podcast/nettle-tea-for-endo?rq=histamine

https://www.theendobellycoach.com/podcast/endo-and-chest-pain?rq=histamine

https://www.theendobellycoach.com/podcast/pycnogenol-endo

https://www.theendobellycoach.com/podcast/endo-ic-sibo?rq=histamine

https://www.theendobellycoach.com/podcast/pots-dysautonomia-with-endo?rq=POTS

https://www.theendobellycoach.com/podcast/endo-and-dysautonomia?rq=POTS

https://www.theendobellycoach.com/podcast/jessica-drummond-endometriosis-mcas-hypermobility-dysautonomia


MCAS and low FODMAP diet

https://med.virginia.edu/ginutrition/wp-content/uploads/sites/199/2020/06/Mast-Cell-Activation-Syndrome-June-2020.pdf

https://pubmed.ncbi.nlm.nih.gov/23644955/

https://pubmed.ncbi.nlm.nih.gov/26976734/

https://drruscio.com/mast-cell-activation-syndrome-clinician-researcher-dr-lawrence-afrin/


Low FODMAP diet and leaky gut/gut microbiome

https://pubmed.ncbi.nlm.nih.gov/34371976/

https://ift.onlinelibrary.wiley.com/doi/10.1111/1750-3841.70072?af=R


Endometriosis and low FODMAP diet

https://onlinelibrary.wiley.com/doi/10.1111/apt.70161

https://www.monash.edu/news/articles/low-fodmap-diet-can-ease-symptoms-of-those-with-endometriosis-study

https://pmc.ncbi.nlm.nih.gov/articles/PMC10754387/

https://pubmed.ncbi.nlm.nih.gov/28303579/


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