Autoantibodies against PTM proteins as biomarkers for lupus

In this podcast, Dr. Javier Rodríguez-Carrio talks to Dr. Pavel Ovseiko and Prof. Laura Coates about the recent paper on gender equity in academic rheumatology which emerged from a EULAR task force. They discuss the current situation of gender equity in academic rheumatology across Europe, the pros and cons of potential interventions to accelerate gender-equitable career advancement in this field and how and these be applied in the short- and long-term. Link to the viewpoint: https://rmdopen.bmj.com/content/8/2/e002518.long Listen to more episodes of RMD Open: https://podcasts.apple.com/gb/podcast/rmd-open-rheumatic-and-musculoskeletal-diseases/id1237127864

Autoantibodies against post-translationally modified proteins (PTM) are described in various rheumatic diseases and facilitate diagnosis and patient stratification. Researchers from the Leiden University Medical Center analysed the presence of autoantibodies against six different post-translational modifications in a cohort of patients with neuropsychiatric lupus. In this podcast, Leendert Trouw, Rory Monahan and Michelle van den Beukel discuss the results of their study with the ARD/RMDopen social media advisor Caroline Ospelt. Read the Open Access related paper: https://rmdopen.bmj.com/content/8/1/e002079 Listen to more episodes of RMD Open: https://podcasts.apple.com/gb/podcast/rmd-open-rheumatic-and-musculoskeletal-diseases/id1237127864

In this podcast, Dr. Javier Rodríguez-Carrio (1) talks to Dr. Tue Kragstrup (2) about the recent safety data on JAK inhibitors emerged after the ORAL Surveillance study. They discuss what is the current situation, the potential strategies to escape a ‘static’ situation, by managing uncertainty in the context of balancing risks, patient preferences and shared-decision process. Read the Open Access related paper: https://rmdopen.bmj.com/content/8/1/e002236 (1) Javier Rodríguez-Carrio (University of Oviedo) (@javierrcarrio); (2) Tue Wenzel Kragstrup (University of Aarhus) (@KragstrupTW)

In this podcast, RMD Open's Social Media Advisor, Dr. Paul Studenic, speaks to Dr. Giovanni Adami, from Universita degli Studi di Verona, Italy, about his population-based cohort study evaluating air pollution-associated risk of developing an immune-mediated disease. By using an Italian-wide patient-dataset, initially designed for fracture risk assessment in women in combination with data for air-quality control stations across Italy, he presents results indicating that long-term exposure to air pollution coincides with a higher risk of developing autoimmune diseases. Read it on the RMD Open website: https://rmdopen.bmj.com/content/8/1/e002055

In this podcast, Caroline Ospelt (Department of Rheumatology, University Hospital of Zurich, Switzerland) talks to Alessia Alunno (Rheumatology Unit, University of Perugia, Italy) about the similarities and differences in the cytokine storm that occurs in COVID-19 patients and people with rheumatic diseases. Link to related paper: https://rmdopen.bmj.com/content/6/1/e001295

A systematic literature review on imaging techniques for diagnosis, outcome prediction and disease monitoring in large vessel vasculitis informing the European League Against Rheumatism recommendations is discussed in this podcast by two of the authors of the paper: Dr. Christina Duftner, rheumatologist at the Medical University Innsbruck, Austria, and Dr. Sofia Ramiro, rheumatologist at Leiden University Medical Center, The Netherlands. Read the paper on the RMD Open website: https://rmdopen.bmj.com/content/4/1/e000612.

RMD Open Editor-in-Chief Professor Bernard Combe talks to Professor Annette van der Helm from Leiden University Medical Center about the use of MR imaging in the diagnosis and classification of rheumatic and musculoskeletal diseases. Professor van der Helm briefly summarises the pros and cons of MR imaging in comparison with the use of CT images, and highlights some of the technical challenges of this technique. For further information on this topic please read this viewpoint article published in RMD Open: https://rmdopen.bmj.com/content/4/1/e000728.

What is peer-review and why is important? EMEUNET, the Emerging EULAR (European League Against Rheumatism) Network, organises a training program in collaboration with the EULAR journals to improve peer review skills of young researchers. Want to know more? Listen to the conversation between Dr Aurélie Najm (Nantes University Hospital, France) and Dr Javier Rodriìguez-Carrio (Universidad de Oviedo, Spain), first author of “Improving the peer review skills of young rheumatologists and researchers in rheumatology: the EMEUNET Peer Review Mentoring Program”, published by the members of the EMEUNET Peer Mentoring subgroup. Read the full article on the RMD Open website: https://rmdopen.bmj.com/content/4/1/e000619 Learn more about EMEUNET here: https://emeunet.eular.org

What mistakes should be avoided in our diet? And what potentially beneficial foods should we be taking? The answers are given by Professor Maurizio Cutolo (Postgraduate School of Rheumatology, University of Genova, Genova, Italy)in this short conversation with Claire Daien (Rheumatology department, Montpellier University, France) recorded at the XVII Mediterranean Congress of Rheumatology, in Genova, Italy, in April 2018. Read the full editorial on the RMD Open website: http://rmdopen.bmj.com/content/4/1/e000591.

To better standardise the evaluation of disease activity of rheumatoid arthritis patients, especially in moderate disease, consensus scores of their medical doctor (MD) global ratings (EGA) are needed. Dr Janet Pope (Western University of Canada) suggests the development of a catalogue of patient scenarios to decrease the wide variability of ranking among rheumatologists. She explains how that could work in this conversation with Dr Paul Studenic (Medical University Vienna, Austria). Read the study “Physician global assessments for disease activity in rheumatoid arthritis are all over the map!” on the RMD Open website: http://rmdopen.bmj.com/content/4/1/e000578.