MED-EL Podcast podcast

Cochlear Anatomy and Its Implications for CI Stimulation

17/03/2026
0:00
32:13
Recuar 15 segundos
Avançar 15 segundos

In this episode, Marcus Schmidt is joined by Prof. Sumit Agrawal and Dr. Peter Nopp to explore how cochlear anatomy shapes cochlear implant design and performance. They discuss breakthrough synchrotron imaging, the variability in cochlear size and structure, and why deep insertion and full cochlear coverage matter for natural, rich sound.

Weblinks:

MED-EL Professional Blog: Incredible Synchrotron Imaging: New Findings in the Human Cochlea | Prof. Helge Rask-Andersen 

Literature Links:

Büchner A, Weller T, Penninger RT, Helpard L, Ladak HM, Agrawal S, Lenarz T, Schurzig D. The Greenwood function shows close alignment with pitch perceived by cochlear implant patients with long, flexible electrode arrays and fine-structure stimulation. Front Neurosci. 2025 Sep 2;19:1624499. doi: 10.3389/fnins.2025.1624499. PMID: 41001584; PMCID: PMC12457772. 

Dorman MF, Natale SC, Noble JH, Zeitler DM (2022). Upward Shifts in the Internal Representation of Frequency Can Persist Over a 3-Year Period for Cochlear Implant Patients Fit With a Relatively Short Electrode Array. Front. Hum. Neurosci. 16:863891. doi: 10.3389/fnhum.2022.863891 

Li H, Helpard L, Ekeroot J, Rohani SA, Zhu N, Rask-Andersen H, Ladak HM, Agrawal S. Three-dimensional tonotopic mapping of the human cochlea based on synchrotron radiation phase-contrast imaging. Sci Rep. 2021 Feb 24;11(1):4437. doi: 10.1038/s41598-021-83225-w. PMID: 33627724; PMCID: PMC7904830. 

Li H, Schart-Morén N, Rohani SA, Ladak HM, Rask-Andersen H, Agrawal S. Synchrotron Radiation-Based Reconstruction of the Human Spiral Ganglion: Implications for Cochlear Implantation. Ear Hear. 2020 Jan/Feb;41(1):173-181. doi: 10.1097/AUD.0000000000000738. PMID: 31008733. 

Mei X, Glueckert R, Schrott-Fischer A, Li H, Ladak HM, Agrawal SK, Rask-Andersen H. Vascular Supply of the Human Spiral Ganglion: Novel Three-Dimensional Analysis Using Synchrotron Phase-Contrast Imaging and Histology. Sci Rep. 2020 Apr 3;10(1):5877. doi: 10.1038/s41598-020-62653-0. Erratum in: Sci Rep. 2020 May 1;10(1):7681. doi: 10.1038/s41598-020-64611-2. PMID: 32245997; PMCID: PMC7125215. 

Micuda A, Li H, Rask-Andersen H, Ladak HM, Agrawal SK. Morphologic Analysis of the Scala Tympani Using Synchrotron: Implications for Cochlear Implantation. Laryngoscope. 2024 Jun;134(6):2889-2897. doi: 10.1002/lary.31263. Epub 2024 Jan 8. PMID: 38189807. 

Mais episódios de "MED-EL Podcast"