800: The "Exhausted" Fibroblast: Reversing Skin Aging & Modulating mTOR with Dr. Rahul Mehta

In this paradigm-shifting episode of Beauty Bytes, I sit down with Dr. Rahul Mehta, the co-founder of Rapalogix Health and former head of R&D at SkinMedica. We dive deep into the future of cellular longevity and why the "do more, laser more, peel more" approach might actually be exhausting your fibroblasts.Dr. Mehta explains the science behind mTOR, the master regulator of our cell cycle, and how constantly keeping it in "growth mode" prevents our skin from repairing itself. We discuss his breakthrough molecule, RLX-201 (Re-!), which inhibits TORC1 to trigger repair pathways without the side effects of systemic rapamycin.We also cover the fascinating data showing how this technology made 56-year-old fibroblasts morphologically resemble 23-year-old cells, effectively reversing cellular aging rather than just masking it.

Grace, beauty, and strength- these are the elements we look for in a face as we allbecome older. While it might be hard for some to fathom the idea of aging, it doesn’t change the fact that it still happens to all of us. That’s why it’s so important to begin to accept this hard truth and learn how to age gracefully instead. In the podcast, I’ll be breaking down different ways you can maintain your beauty at any age. From natural, topical solutions like sunscreen to building volume with filler, here are different courses of action you can follow to preserve the appearance of your youth.

In this cutting-edge episode of Beauty Bytes, I sit down with Cristiana Banila, the Chief Scientific Officer and co-founder of Mitra Bio, to discuss the revolutionary field of skin epigenetics. We explore the difference between genetics (the hardware) and epigenetics (the operating system) and how non-invasive tape stripping technology allows us to measure biological age and cellular damage without a single biopsy. Cristiana reveals fascinating data on how sun-protected skin is biologically 3.8 years younger than exposed skin, and we tackle a controversial finding from her research: why short-term retinoid use might actually accelerate biological aging by increasing inflammatory markers . We also discuss the future of skin cancer detection and why "resilience" is the new anti-aging standard.

In preparation for Valentine's Day, we are talking about the top 10 ways females can improve their attractiveness. Female beauty is such an amazing aspect of human life and that's why I have dedicated my life to working in aesthetic medicine. I love helping women feel beautiful on both the inside and out. The idea of female beauty is more than just an artificial aspect of women, but rather an all-encompassing characteristic to describe all the amazing facets of a woman. Facial harmony, universal beauty, and internal confidence are all various components of attractiveness that I seek to improve in all my patients. Listen on to find out my tips and tricks to feel and look more attractive!

In this high-energy episode of Beauty Bytes, I sit down with Dr. Latt Mansor, a world expert in physiology and metabolism with a PhD from the University of Oxford. We dive deep into the science of ketones—the body's natural "super fuel"—and why you don't need to be on a strict keto diet to reap the benefits.I actually take a shot of Ketone-IQ during the episode, and you can hear me get into the "zone" in real-time! . Dr. Mansor explains how exogenous ketones can banish brain fog without the caffeine jitters, suppress appetite by regulating ghrelin and leptin, and even positively influence our epigenetics and gene expression. We also bust common myths about ketoacidosis and discuss why walking might be the most underrated biohack for breaking through fat loss plateaus .

Healthy diet, vitamin supplements, and essential nutrients- do you know what they say: you are what you eat this concept applies, especially when you are looking to improve the appearance of your skin and prevent physical signs of premature aging! According to Dave Asprey, the founder of Upgrade Labs and Father of Biohacking, the secret to maintaining youthful skin isn't just found in your topical creams but also in the food you eat in this podcast, I go over what types of anti-aging ingredients you should be looking for in your food, and where you can find them! 

In this episode of Beauty Bytes, I am exploring the frontier of needle-free regenerative medicine with Dr. Sanjay Batra, a globally recognized scientist and the creator of Juvasonic. We discuss how his device uses a unique combination of sonic vibration and dermabrasion to open the stratum corneum for 10-15 minutes, allowing large molecules like exosomes, polynucleotides, and PRP to penetrate deep into the dermis without a single needle prick.Dr. Batra shares why microneedling might not be the best delivery method for serums (hint: the bleeding actually pushes products out!) and reveals incredible data on using this technology for hair density and restoration . We also cover a fascinating off-label use: how Juvasonic can potentially break down filler nodules (like Radiesse lumps) in just seconds without invasive measures . This is the future of pain-free, high-compliance aesthetic care.

In this Five Minute Friday, I am revealing the one supplement most women avoid because they think it causes bloating or bulk—but a new study proves it might actually be the missing link for your brain health . If you are struggling with "menopause brain," afternoon fatigue, or sudden anxiety, the solution might not be a prescription or an expensive wellness trend, but something incredibly simple that has been hiding in the bodybuilding aisle all along . Tune in to find out why this specific compound is a game-changer for the frontal cortex (the decision-making part of your brain) and hear the specific dosing protocol I use to stay sharp during jet lag and all-nighters . We are redefining what it means to be strong—mentally and physically

In this visionary episode of Beauty Bytes, I am saying goodbye to the "filler fatigue" of 2025 and unveiling my Top 10 Aesthetic Predictions for 2026. This isn't just about trends; I’m mapping out a paradigm shift toward hyper-personalization and regenerative medicine that will change how we treat aging forever. I explain why the era of overfilling is dead and how I am pivoting to "undetectable" results using micro-tox, strategic lifting, and collagen biostimulators. I also explore the cutting-edge future of AI diagnostics, where digital avatars will allow me to simulate your aging trajectory and show you treatment outcomes years in advance . We dive deep into the science of skin senescence, targeting "zombie cells" to restore resilience rather than just treating wrinkles . From turning on your body's mTOR cycles for cellular repair to the rise of collagen banking for Gen Z, I’m sharing exactly where the world of aesthetics is heading next year.

Resolutions, better habits, and goals- In this Five Min Friday, we'll be going over my new year resolutions for 2024! With just a little over a week left until we dive into a brand new year, people are beginning to create lists with goals they want to achieve. As we prepare for the classic New Year, New Me posts to flood social media, let's take a look at what meaningful changes I have planned for myself!