Why America’s Poorest State Is Richer Than France (#251)

What if we could rewrite the code of life—just like editing a Word doc?Gene-editing pioneer David Liu takes us behind the scenes of the revolutionary tools transforming medicine. He’s the Harvard scientist who invented base editing—a breakthrough that lets scientists fix a single DNA letter to correct genetic disease at its root.This is science fiction come to life—and it's happening now. He edits DNA like we edit text. Come meet the man who's changing lives, one letter at a time. 

What if music, color, scent, and art could actually change your brain? Science now shows they do.Join Susan Magsamen, Executive Director of the International Arts + Mind Lab at Johns Hopkins, as she explores how art and beauty impact our brains and well-being. From the transformative power of music to the subtle magic of sensory environments, she reveals how simple aesthetic moments can boost your health and joy.

Mississippi is richer than France. No, really. The poorest U.S. state now has a higher GDP per person than France, the U.K., Italy, and Spain. How did that happen? Don’t miss this eye-opening episode with George Mason University's Tyler Cowen. 

China is on the march, is very determined, and has some significant advantages over the U.S. What are they and how should we respond? Two esteemed China experts, former U.S. Deputy Secretary of State Kurt Campbell and National Security Council Deputy Senior Director for China Rush Doshi, say the key is to counter China’s enormous scale by finding common cause with allies.  Listen, and learn a lot.

As the dust settles on the 2024 presidential election, now is an excellent time to take a fresh, clear-eyed look at what really happened. Join us as Larry Bartels, political scientist extraordinaire and Co-Director of Vanderbilt University's Center for the Study of Democratic Institutions, explains why Trump’s win was not unusual and the roles played by the economy, loyalty to the political parties, and Trump’s unique personality.

What if your phone is quietly changing your brain—and your relationships? The brilliant Christine Rosen explores how digital life is reshaping everything from childhood to public discourse, often in ways we barely notice. With insight and urgency, she challenges the assumptions driving our always-online world.  This conversation will make you see your screen—and our society—differently.

Ever wondered why we sometimes act irrationally, even when it’s not in our best interest? Ori Brafman has, and his answers are enlightening. Here, he talks about the hidden forces and human emotions that make us act irrationally, how pre-dispositions and labeling people can lead to irrationality, how we can become more rational, and more.

Are we shaped by our genes or by our environment? For centuries, this question has fueled one of science's most enduring debates. But the truth is more shocking—and more fascinating—than either side ever imagined. Princeton professor Dalton Conley reveals why we need to abandon the idea of "nature vs. nurture" and embrace a radically new understanding of human development.

Is today's economy delivering for American workers? According to Georgetown University professor Michael Strain, the answer is absolutely “yes,” despite populist rhetoric… and there’s convincing data to back that up. Why is the American Dream in doubt? How can it be strengthened? Listen to this inspiring conversation for answers.

All across America, critical government infrastructure projects — building EV charger stations, expanding broadband, building rail tunnels — are stalled or abandoned. According to trail-blazing government reformer Philip Howard, powerlessness to get things done has become a defining feature of America. Listen and learn why, and how things can change.