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The Explosion Of Fentanyl Addiction In Mexican Border Cities And What's Driving It (10/27/25)

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In recent years, towns along Mexico’s northern border with the United States—such as Tijuana and other cities in Baja California, Sonora and elsewhere—have been hit by a sharp rise in use of the synthetic opioid fentanyl. Traditionally, much of the public-health focus in Mexico had been on heroin or methamphetamine use, but mounting evidence shows that fentanyl has begun to penetrate these border communities, altering drug-use patterns in ways that raise new risks. Studies show that fentanyl is increasingly tied to the local illicit-drug supply—often mixed into powder heroin or pressed into pills for use or export.


This surge in fentanyl use is compounded by weaknesses in local addiction-treatment infrastructure and traditional harm-reduction services. In border towns, factors like deportation (for example in Tijuana over 40 % of people who inject drugs report having been deported from the U.S.) greatly increase vulnerability.   At the same time, surveillance in Mexico for overdoses tied to fentanyl is minimal, and life-saving tools like naloxone are much less available than in the U.S. Without strong public-health responses, the rising availability of high-potency synthetic opioids means more rapid escalation from use to overdose, particularly in areas already grappling with poverty, stigma and limited services.


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