
Hormone Creams & Wrinkles: The Truth About Estradiol vs Estriol | PYHP 187
13.10.2025
0:00
20:06
Should you use estradiol cream on your face? Dr. Valerie Davidson and Dr. Robert Maki explain why estriol (E3) is a gentler, safer alternative for wrinkles, melasma, vaginal health, and hormone balance during perimenopause and menopause. They share the risks of estradiol absorption, why it can throw off your HRT program, and why estriol is often the better choice—for both skin care and vaginal tissues. You’ll also learn about systemic vs local hormone use, melasma risk, and the real-world challenge of getting access to estriol. If you have a question, please visit our website and click Ask the Doctor a
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