Metformin: A Fresh Angle for Treating Knee Osteoarthritis - Frankly Speaking Ep 445

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-449 Overview: In this episode, we discuss new evidence linking high compliance with the Dietary Approaches to Stop Hypertension (DASH) diet to lower risks of colorectal cancer, reinforcing the DASH diet’s well-established role in managing hypertension while also highlighting its potential to reduce cancer risk. Gain practical insights into translating these findings into actionable nutrition guidance to support your patients’ overall health. Episode resource links: Explain the risk factors for development of colorectal cancers Review the Dietary Approaches to Stop Hypertension (DASH) and discuss the proposed mechanisms for colorectal cancer reduction by following this approach Apply evidence from a meta-analysis to support dietary counseling strategies aimed at cancer prevention in clinical settings Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-448 Overview: Join us to discover how flavan-3-ols, found in tea, cocoa, and select fruits, can support cardiovascular prevention. Learn how to translate emerging evidence on blood pressure and vascular health into practical dietary guidance that empowers your patients and complements standard hypertension care. Episode resource links: European Journal of Preventive Cardiology (2025) 00, 1–13. https://doi.org/10.1093/eurjpc/zwaf173 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-447 Overview: New data show that quitting smoking—even at age 65 or 75—can still add years to life. In this episode, we review the latest evidence on life expectancy gains and equip you with effective, evidence-based tools to support tobacco cessation and motivate patients at any age. Episode resource links: Le,Thuy TT., Mendez, D. , & Warner, K. (2024). The Benefits of Quitting Smoking at Different Ages. American Journal of Preventive Medicine, 67 (5), 684-688. https://doi.org/10.1016/j.amepre.2024.06.020.    What are the treatments for tobacco dependence? National Institute on Drug Abuse https://nida.nih.gov/publications/research-reports/tobacco-nicotine-e-cigarettes/what-are-treatments-tobacco-dependence Smokefree.gov offers Apps, counseling, texting support, tools and tips for your patient to build your quit plan Selby, P., & Zawertailo, L. (2022). Tobacco Addiction. The New England journal of medicine, 387(4), 345–354. https://doi.org/10.1056/NEJMcp2032393 Guest: Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-445 Overview: Managing knee osteoarthritis (OA) in patients with obesity can be challenging, especially when standard treatments fall short. In this episode, we discuss emerging evidence on the use of metformin to reduce knee pain in patients without diabetes and explore how this option could expand your approach to OA management. Episode resource links: Pan F, Wang Y, Lim YZ, et al. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial. JAMA. 2025;333(20):1804-1812.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-442 Overview: Listen in as we review the USPSTF’s recently proposed recommendations for screening women who are at risk for developing osteoporosis. Gain confidence to navigate these changes and engage patients in shared decision-making to ensure timely, evidence-based preventive care. Episode resource links: JAMA. 2025;333(6):498–508. doi:10.1001/jama.2024.27154 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-441 Overview: Explore the evidence behind inspiratory and expiratory strength training to improve sleep quality, reduce daytime fatigue, ease COPD symptoms, and lower blood pressure. This episode offers practical guidance on how you can integrate this simple, affordable intervention to support better breathing and overall health in your patients. Episode resource links: OSA: Journal of Sleep Research. 2024;33(3):e13941. doi:10.1111/jsr.13941. Sleep & Breathing = Schlaf & Atmung. 2022;26(4):1527-1537. doi:10.1007/s11325-021-02536-4. HTN: Journal of Applied Physiology (Bethesda, Md. : 1985). 2020;129(3):449-458. doi:10.1152/japplphysiol.00024.2020. COPD: Chest. 2003;124(4):1357-64. doi:10.1378/chest.124.4.1357. Sleep: Sleep. 2016;39(6):1179-85. doi:10.5665/sleep.5826. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-440 Overview: Explore current and emerging treatments for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition with no known cause or cure. Learn how oxaloacetate may offer new hope for patients struggling with ME/CFS, and gain practical guidance to support informed, evidence-based conversations with your patients. Episode resource links: Cash A, Vernon SD, Rond C, Bateman L, et al. RESTORE ME: a RCT of oxaloacetate for improving fatigue in patients with myalgic encephalomyelitis/chronic fatigue syndrome. Front Neurol. 2024 Nov 27;15:1483876.  Cash A, Kaufman DL. Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial. J Transl Med. 2022 Jun 28;20(1):295.  CDC ME/CFS Basics Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-439 Overview: Nocturnal leg cramps (NLCs) are common in older adults, but current treatments often fall short or carry risks. Listen in as we explore new evidence on the safety and efficacy of vitamin K2 as a potential treatment for NLCs. Come away with practical insights to help you improve the sleep and quality of life of your patients. Episode resource links: JAMA Intern Med. 2024;184(12):1443-1447. doi:10.1001/jamainternmed.2024.5726 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-438 Overview: In this episode, we review a major umbrella study linking physical activity to improvements in memory, executive function, and general cognition—offering you practical insights to guide patient counseling and provide evidence-based, nonpharmacologic strategies for dementia prevention and cognitive enhancement. Episode resource links: Singh B, Bennett H, Miatke A, et al. Br J Sports Med. doi:10.1136/ Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-435 Overview: In this episode, we discuss how screen time—from adolescence through adulthood—can disrupt sleep more than we might realize. Hear what the latest research says about topics like blue light and sleep duration, discover practical strategies to sleep smarter in this digital world, and learn how sleep deprivation can impact the health of your patients. Episode resource links: Zhong, C., Masters, M., Donzella, S. M., Diver, W. R., & Patel, A. V. (2025). Electronic Screen Use and Sleep Duration and Timing in Adults. JAMA Network Open, 8(3), e252493-e252493. Liu, Y. (2016). Prevalence of healthy sleep duration among adults—United States, 2014. MMWR. Morbidity and mortality weekly report, 65. Centers for Disease Control and Prevention (CDC). (2017). Announcement: sleep awareness week, April 23–29, 2017. Morb Mortal Wkly Rep (MMWR), 66(15), 411. Chaput, J. P., Dutil, C., Featherstone, R., Ross, R., Giangregorio, L., Saunders, T. J., ... & Carrier, J. (2020). Sleep duration and health in adults: an overview of systematic reviews. Applied Physiology, Nutrition, and Metabolism, 45(10), S218-S231. Hartley, S., Royant-Parola, S., Zayoud, A., Gremy, I., & Matulonga, B. (2022). Do both timing and duration of screen use affect sleep patterns in adolescents?. Plos one, 17(10), e0276226. Salfi, F., Amicucci, G., Corigliano, D., D’Atri, A., Viselli, L., Tempesta, D., & Ferrara, M. (2021). Changes of evening exposure to electronic devices during the COVID-19 lockdown affect the time course of sleep disturbances. Sleep, 44(9), zsab080. He, J. W., Tu, Z. H., Xiao, L., Su, T., & Tang, Y. X. (2020). Effect of restricting bedtime mobile phone use on sleep, arousal, mood, and working memory: a randomized pilot trial. PloS one, 15(2), e0228756. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]