278: Patrick Coles – The Toxin Sequestration Theory

Patrick Coles “I think it’s very important to differentiate between defence mechanisms and actual diseases.” – Patrick Coles   Patrick obtained his PhD in Chemical Engineering at Berkeley and his MPhil in Biochemistry at Cambridge. He has co-authored over 170 research papers in physics and computer science. He invented the Toxin Sequestration Theory (TST) of cancer, and he is currently rewriting the theory of disease in terms of toxicity.   Patrick’s Top Tips Trust your body. Don’t try to attack your body’s defences. Things like fever, allergies and inflammation are your body protecting you. Give it a healthy, nourishing diet and it’ll do the rest. Carnivore is the diet lowest in toxins. Keto is very good too, because it cuts out sugar, fructose and seed oils. Carnivore just takes it one step further. Keep an open mind and question things. Don’t take things at face value. Trust your own ability to think logically, because you might reason things through better than your doctor   Resources Mentioned Toxic Superfoods by Sally K. Norton https://link.amazon/B02jGaVrK   Garrett Smith, the Nutrition Detective: NutritionDetective.com Garrett Smith’s Love Your Liver Program Also mentioned: Dr Eric Berg, Stephanie Seneff, Tom Cowan, Thomas Seyfried and Aajonus Vonderplanitz (the Primal Diet). Connect with Patrick Coles   YouTube: @OxalateWarrior Substack Instagram Facebook Facebook (personal profile)   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Joseph Reyes “They were just telling me I need a surgery, and then I just started eating meat, a lot of beef, chicken. How can this be?” Joseph Reyes   Joseph Reyes is a father of two who works in e-commerce and has always maintained an active lifestyle since he was young through tennis, CrossFit, and other forms of training. Despite staying active, he spent over a decade dealing with chronic skin conditions, joint pain, and recurring injuries. What began as a search for relief from chronic tennis elbow eventually led him to the carnivore diet and a broader shift in his health, mindset, and physical performance. His experience led him to question long-held beliefs about nutrition, his worldview, unlearn many of the cultural norms surrounding food, and rediscover what it feels like to be healthy, active, and capable again.   Joseph’s Top Tips Keep it as simple as possible. You don’t have to overcomplicate things with recipes or supplements or trying to make everything perfect. Just get started, then tweak and adjust from there. Give your body time to adjust. Some people take 30 days, some 60, some even 90. Make sure you get enough salt and fluid, and look into your fat to protein ratio. If you hit problems after a year, don’t throw it all away. It could just be a simple tweak. For Joseph it was removing eggs and dairy. It could also be stress, training too hard, or not eating enough.   Resources Mentioned Toxic Superfoods by Sally Norton Dave Mac, No Carb Life Carnivore Evolution with Victoria Olson Jackie on Carnivore Evolution Jackie on Hungry Mind Journey Dr Anthony Chaffee, Dr Shawn Baker, Steak and Butter Gal and Mikhaila Peterson, whose videos helped Joseph find carnivore Connect with Joseph Reyes YouTube: Hungry Mind Journey Instagram: @hungrymindjourney   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Jonathan Griffiths Jonathan Griffiths is a professional bodybuilder, nutritionist (BSc in Human Nutrition), and elite fitness coach. As the founder of Carnivore Muscle, Jonathan specializes in helping individuals build muscle, optimize athletic performance, and repair metabolic function through zero-carb, animal-based nutrition. By combining rigorous sports science with real-world experience on the bodybuilding stage, he empowers clients to achieve peak conditioning and long-term health. Key Quote “Keep working when the spotlight isn’t on you, ’cause that’s the time that you make the most progress. ‘Cause most of the time the spotlight is not on you.” – Jonathan Griffiths Jonathan’s Top Tips Keep working when the spotlight isn’t on you. That’s when you make the most progress, and most of the time the spotlight isn’t on you. Follow a carnivore or at least an animal-based diet. Be aware of plant toxins and make nutrient-dense animal foods the focus. Recovery is the bottleneck for building muscle and losing fat. If you don’t recover, you don’t get better. Don’t quit. Build yourself a good support system. The people around you mould you, so make sure they mould you the right way.   Resources Mentioned Billy Doe Meats – the farm in Illinois that sent Angela the non-aged lamb, goat and veal she could finally eat  Girdle Bridge Farm – where Angela got her fat while in England  Whole30 – the book Angela read before trying Whole30 for six months  Connect with Jonathan Griffiths Website: carnivore-muscle.com YouTube: Carnivore Muscle Pro Instagram: @carnivoremusclepro Coaching and contact: [email protected]   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Angela Lerro  Angela Lerro, also known as the Meat Based Medium, is a Medical Intuitive and Integrative Healer specializing in nervous system regulation, emotional healing, and mind-body wellness.  After navigating a lifelong journey with chronic illness, Angela discovered that a carnivore diet was a powerful missing piece in her own healing, complementing the mind-body, energetic, and intuitive work she had practiced for years.  Today, she brings these worlds together through a unique approach blending intuitive insight, energy healing, nervous system regulation, ancestral wellness principles, nutrition, and holistic health. With more than a decade of experience in transformational healing work, Angela helps individuals look beyond symptoms to explore the deeper physical, emotional, and energetic patterns that may be keeping them stuck.  At the heart of her work is the belief that healing isn’t about following one perfect diet or protocol, but learning to reconnect with the body, trust its signals, and become an active participant in your own healing. Her work explores the intersection of ancestral health, human optimization, consciousness, intuition, and emotional well-being.  Key Quote “I encourage people to look further than just the diet to heal them. Because most of the time, the answers aren’t just on our plate. They’re also in our soul.”  Angela Lerro    Angela’s Top Tips Trust the process. You may not see the results you’re looking for right at the beginning. Let go of your fears, have blind faith, and keep moving forward even when you feel like you want to go back.  Have grace with yourself. Love yourself through the difficult times. Have grace when you make a mistake, if you cheat on your diet, or if you’re not feeling optimal and need more rest. Think kind thoughts and speak kind thoughts.  Healing starts in the mind, and we are one decision away from living our best life. Everything you do is a decision. Ask yourself what’s stopping you from making a decision to do something better for you, and remember that not making a decision is a decision.    Resources Mentioned Billy Doe Meats – the farm in Illinois that sent Angela the non-aged lamb, goat and veal she could finally eat  Girdle Bridge Farm – where Angela got her fat while in England  Whole30 – the book Angela read before trying Whole30 for six months  Connect with Angela Lerro Instagram: @meatbasedmedium  Facebook: Angela Lerro  Facebook group: Histamine Intolerant Carnivores    Website  meatbasedmedium.com      The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Felix Mueller Felix Mueller is a health author, metabolic-health coach, and the founder of REVERSING PKD. Diagnosed with autosomal dominant polycystic kidney disease (more than 1 in 1000 people have it) at age 16, Felix spent years searching for ways to influence a condition he had been told was largely beyond his control. His research led him to therapeutic ketosis, fasting, metabolic flexibility, and the emerging science connecting mitochondrial dysfunction, insulin resistance, inflammation, and abnormal cell growth. By applying these principles to his own life, Felix has seen significant improvements in his metabolic health and kidney-related markers, including a reduction in total kidney volume and much increased kidney function. He is the author of Reversing Polycystic Kidney Disease: The PKDproof Program, which includes more than 150 scientific references and a foreword by Dave Asprey. Through his book, podcast, online community, and one-to-one coaching, Felix helps people with PKD better understand nutrition, ketosis, fasting, protein intake, stress, environmental factors, and the practical realities of making sustainable lifestyle changes. Felix’s work combines scientific curiosity with lived experience. His mission is to challenge the idea that people with chronic disease are powerless, and to help them become active participants in their own health journey. Key Quote “It’s not really about chasing super high ketones. This is a marathon, not a sprint.” – Felix Mueller   Felix’s Top Tips Don’t chase super high ketones. If you’re doing this long term, it’s a marathon, not a sprint, so make it sustainable. Make nutrient density and high-quality protein your top priority. Replace the foods you remove instead of just restricting yourself, for example with keto versions of your treats, so you don’t feel deprived. If you have kidney issues and need to limit protein, replace some of it with amino acids. Prioritise sleep, and prioritise salt. Both make a big difference to your quality of life on a ketogenic diet.   Felix’s Books Reversing Polycystic Kidney Disease: The PKDproof Program: A low-carb, high-nutrient approach to kidney health   Resources Mentioned The Bulletproof Diet by Dave Asprey Cancer Resolution by Mark Lintern Cancer as a Metabolic Disease by Thomas Seyfried Toxic by Dr Neil Nathan KetoFast by Dr Joseph Mercola Mycotox panel by Mosaic Diagnostics (urine test for mould) KetoneAid (ketone ester) Felix’s YouTube interviews with Thomas Seyfried and Mark Lintern: https://www.youtube.com/@REVERSINGPKD Connect with Felix Mueller Facebook Page: https://www.facebook.com/profile.php?id=100086423605083 Facebook Group: https://www.facebook.com/groups/reversingpkd Instagram: https://instagram.com/reversingpkd YouTube: https://www.youtube.com/@REVERSINGPKD   Website  https://reversingpkd.com   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Brendan Reesor Brendan is the author of Beyond The Pale, Anemia: The Visible Yet Unseen Cause of Mental Illness & Gender Dysphoria. After seeing improvements to his own mental health and outlook on life, Brendan began to see a pattern around anemic pallor, plant-based diets, mental illness, woke ideology, and gender dysphoria. His work connects physical health, nutrition, and physiology to mental health, psychology, spirituality, emotions, philosophy and more. Brendan addresses the most important yet overlooked factor in mental illness: oxygen. There is simply nothing more important for the brain than oxygen, and it’s not easy to get enough of it delivered to the brain, especially when anemic. Brendan focuses on blood and oxygen to better understand diverse phenomena, including depression, anxiety, hallucinations, dissociation, nightmares, irrational thinking, blushing, mass hysterias, and more. Key Quote “It doesn’t matter how much of your RDA is on the package. It doesn’t matter if the spinach says that you’re getting so much iron. It’s just on paper. In reality, you’re not getting any of it.” — Brendan Reesor   Brendan’s Top Tips Learn to recognise and understand your symptoms — pallor, bruising, restless legs, hair and skin changes are all signals, not things to just shrug off. Eat more red meat, and avoid vegetables high in antinutrients (oxalates, tannins, soy protein, phytates) that block iron absorption. Don’t give up on yourself — improving your health is worth it, even if you never become “the perfect specimen.”   Brendan’s Books Beyond The Pale: Anemia, The Visible Yet Unseen Cause of Mental Illness & Gender Dysphoria   Connect with Brendan Reesor Instagram: https://www.instagram.com/brendan.reesor/ Facebook Group: https://www.facebook.com/groups/1194973812538756 YouTube: https://www.youtube.com/@SubstituteProfessor   Website https://www.brendanjreesor.com/   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Dr Abs  Dr Abs is a clinician that provides, teaches and researches cosmetic, sports and longevity medicine around the world. He has worked with patients to address metabolic disease, improve sports performance and help longevity goals. He has worked and continues to work all around the world from Los Angeles to London to Dubai to New Zealand and many many more. His biggest influence in this area of life is Nutrition and Physical Degeneration by Weston Price and he cites many other people in this space as those he continues to learn from such as Professor Bart Kay, Zsofia Clemens, Richard Smith, Anthony Chaffee, Robert Kiltz and much more. Key Quote “When you are trained to be obedient, is it any wonder that a drug company can tell you, ‘This thing’s amazing,’ you go and believe it, and then prescribe it?” — Dr Abs Dr Abs’ Top Tips “There are no top tips. There is only hard effort.” See above See above   Resources Mentioned Sachdeva et al. 2009 — cholesterol levels and heart attack study Bendor et al. 2021 — ancestral diet composition research Cleave 1974 — timeline of diabetes development Zsofia Clemens — cold turkey carnivore transition approach NICE (National Institute for Health and Care Excellence) guidelines – https://www.nice.org.uk   Connect with Dr Abs Instagram – https://www.instagram.com/@doctor.abs YouTube – https://www.youtube.com/@Dr_Abs   Website drabs.clinic – https://www.drabs.clinic   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Shashikant Iyengar  Shashikant Iyengar is a leading metabolic health coach from India and the founder of Metabolic Health India®. After spending over 35 years in the pharmaceutical industry with companies like Abbott and Pfizer, he transitioned into full-time metabolic health coaching in 2022 following his own successful remission from Type 2 diabetes through a low-carbohydrate lifestyle. He has been in sustained Type 2 diabetes remission since 2015 and is widely recognized for promoting practical, culturally adaptable low-carb nutrition for Indians, especially in vegetarian settings. Shashikant has coached clients globally across diabetes, obesity, fatty liver, hypertension, and metabolic syndrome. He is the organizer of India’s Metabolic Health Conference (MHC) series and a faculty member with Nutrition Network. He has delivered corporate metabolic health talks at organizations. Shashikant is also the author of a published long-term Type 2 diabetes remission case study documenting his own decade of remission using a real-world Indian low-carb approach. Through education, conferences, podcasts, and social media, he continues to advocate for improving metabolic health awareness in India and globally. Key Quote “Even if I am able to help 10 people out of one point 4 billion, it is still worthwhile.” — Shashikant Iyengar Shashikant’s Top Tips Eat real food. Prioritise protein. Clean up your lifestyle in terms of exercise, sleep, and stress.   Resources Mentioned   Metabolic Health Conference — India’s first low-carb conference series, which Shashikant organises Shashikant’s YouTube channel Connect with Shashikant Iyengar Twitter:  https://x.com/shashiiyengar https://x.com/MetabolicHConf   Facebook Profile:  https://www.facebook.com/shashikant.iyengar/ https://www.facebook.com/shashikant.iyengar.9/   Instagram:  https://www.instagram.com/shashikant_iyengar/ LinkedIn: https://www.linkedin.com/in/shashikantiyengar1/ YouTube: https://www.youtube.com/@shashiiyengar   Website Details https://www.metabolichealthindia.com/ https://www.metabolichealthconference.com/   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Craig Emmerich  Craig Emmerich graduated in Electrical Engineering who has spent the last 16 plus years researching nutrition and working with thousands of clients along side his wife Maria Emmerich. He is an international best selling author of the “Keto: The Complete Guide” and “The Carnivore Cookbook”. He uses his knowledge of how our bodies work to help clients heal and lose weight leveraging their biology to make it easy. Craig has helped hundreds of thousands of people regain their health and vitality with a strong focus on the science of human nutrition. Craig has been keto for over 17 years and carnivore for over 6 years to help treat his chronic Lyme disease and CIRS pain. Key Quote “You can eat a 1,000-calorie milkshake, and two hours later you’re like, ‘I could eat something.’ But if I stick 14 eggs in front of you and tell you to eat them all, you probably won’t eat till tomorrow.” — Craig Emmerich Craig’s Top Tips Go back to whole foods — no matter which specific way of eating you follow, this alone helps most people. Move more, even outside the gym — small movement throughout the day (NEAT) adds up more than most people realise. Get outside — fresh air, sunlight, and vitamin D matter more than people give them credit for.   Craig’s Book The Art of Metabolic Health — Craig and Maria Emmerich’s new release. ketomaria.com Resources Mentioned None specifically referenced beyond Craig’s own book. Connect with Craig Emmerich Instagram: @craig_r_emmerich Twitter/X: @craig_emmerich YouTube: @craigemmerich Website Details ketomaria.com   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.

Matthew Caruana  Matthew built a career in professional cookery, becoming a Head Chef and working internationally. A serious motorbike accident in 2016 pushed him to take control of his health, leading to an eight and a half stone weight loss through a ketogenic diet. He began creating and sharing keto desserts, which grew into a following and a recipe book. After losing his job in 2020, he turned that passion into a business, becoming the UK’s first artisan keto chocolatier and going on to win multiple awards. Key Quote “I definitely feel depression from eating carbs, which is a crazy thing to say. I feel so much more sluggish and, you know… when you actually put the carbs back in, you feel so much worse, physically and mentally.” — Matthew Caruana Matthew’s Top Tips     Get a proper night’s sleep. It’s free, and it’s one of the biggest things that helps with impulse control around food.     Remove the treats from your house. If there’s friction between you and the bad stuff (having to get in the car and drive to the shop, for example), you’re far less likely to break.     Don’t punish yourself if you slip up. If you get carbed, go to bed, and the next day draw a line under it. Beating yourself up just spirals into eating more sugary things.   Matthew’s Book Everyone Deserves Dessert — available exclusively via Matthew’s website (not on Amazon). Resources Mentioned     The Daisy Garland — the charity that helped Matthew’s friend’s daughter access a therapeutic ketogenic diet for juvenile epilepsy.     Siobhan Huggins — mentioned in relation to an intentional carb-reintroduction experiment. Episodes 016 & 017 https://fabulouslyketo.com/podcast/016 https://fabulouslyketo.com/podcast/017 Connect with Matthew Caruana Facebook Profile: https://www.facebook.com/SweetKetoChef Facebook Page: https://www.facebook.com/sweetketochefofficial Instagram: https://www.instagram.com/sweet_keto_chef/ Website https://www.sweetketochef.co.uk/   The Fabulously Keto Diet & Lifestyle Journal: A 12-week journal to support new habits – Jackie Fletcher If you have enjoyed listening to this episode – Leave us a review By leaving us a review on your favourite podcast platform, you help us to be found by others. Connect with us on social media https://www.instagram.com/FabulouslyKeto1 https://twitter.com/FabulouslyKeto https://www.youtube.com/@FabulouslyKeto Facebook Group: https://www.facebook.com/groups/FabulouslyKeto   Music by Bob Collum   Recommend a guest We would love to know if you have a favourite guest you would like us to interview. Let us know who you would like to hear of if you have a particular topic you would like us to cover. https://fabulouslyketo.com/recommend-a-guest We sometimes get a small commission on some of the links, this goes towards the costs of producing the podcast.