Can Calyxo CEO Catanese Lead New Company Down Familiar Tract to Build Another Urology Powerhouse

In this episode of the DeviceTalks Weekly Podcast, host Tom Salemi is reassured by his conversation with Joe Catanese, CEO of Calyxo, a urology startup that has developed a system designed to simplify kidney stone removal. Catanese previously helped build Neotract, a urology startup that was acquired by Teleflex for more than $1 billion. Now, he's leading another potential gamechanger and may have his sights set on an IPO. Speaking of gamechangers, HistoSonics continues to shatter fundraising expectations. The company recently completed a financing round that valued it at $3.75 billion. In this week's FOMO interview, HistoSonics President and CEO Mike Blue speaks with MassDevice Editor Chris Newmarker during a keynote conversation at DeviceTalks Minnesota. In this excerpt, Blue reflects on the company's first major fundraising round, which attracted high-profile investors including Jeff Bezos and Peter Thiel, and shares his perspective on just how large the opportunity for histotripsy could become. But first, Tom and Jim Hammerand, managing editor of Medical Design & Outsourcing, discuss AI—or LLMs, or whatever term you prefer. Is the hype beginning to fade? And what should the industry make of the recent announcement from Midjourney Medical? *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:05:29) - AI Talk with Jim Hammerand, managing editor, Medical Design & Outsourcing(00:24:46) - DeviceTalks Minnesota interview excerpt - Mike Blue, CEO and President, Histosonics(00:41:44) - Keynote Interview with Joe Catanese, CEO and President, Calyxo

In this episode of the DeviceTalks Weekly Podcast, Host Tom Salemi visits his MedTech happy place — renal denervation — with Recor Medical COO Helen Reeve Stoffer. Reeve Stoffer joined the company shortly before the bottom fell out of the renal denervation market in 2014. This interview picks up from that point and follows Recor's pursuit of FDA approval to where denervation technology may be applied next. This week’s FOMO features a portion of a keynote interview with Manny Villafaña, MedTech legend and CEO of Medical 21. The conversation took place at DeviceTalks Minnesota and focuses on the dream that saved St. Jude Medical. Skyler Rivera, associate editor of MassDevice, gives us a preview of her upcoming feature in Medical Design & Outsourcing magazine on the race to provide telesurgery capabilities to surgical robotic systems. *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:02:42) - Associate Editor Skyler Rivera's path the MedTech (and MassDevice)(00:06:00) - MDO covers the race for robotic telesurgery platforms in stroke(00:11:12) - Rivera reviews the race leaders(00:16:30) - FOMO Studio - Manny Villafana, MedTech Legend and CEO of Medical 21(00:28:19) - Keynote Interview - Helen Reeve Stoffer, COO, Recor Medical

In this episode, Host Tom Salemi is joined by Darla Hutton, Intuitive’s global vice president of cardiac surgery, to discuss the surgical robotics giant’s return to cardiac surgery. Intuitive famously aimed for the heart at its outset but pivoted when cardiac surgery proved too complicated. Today, heart patients and surgeons are pushing for minimally invasive procedures, and Hutton, a former cardiac surgery OR nurse, has been tapped to lead the company’s push into an increasingly competitive specialty. But first, Harmonic Drive’s Bill Frey, regional sales engineer, joins us in the FOMO Studio. Go to HarmonicDrive.net for more information. Filling in for MassDevice’s Chris Newmarker, Senior Editor Sean Whooley wraps up the five biggest stories to come out of the American Diabetes Association meeting — Abbott, Senseonics, Sequel, Dexcom, and Insulet. *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:04:43) - Abbott studies reinforce DKA opportunity following dual sensor milestone(00:07:13) - Senseonics study supports Eversense 365 CGM with automated insulin delivery tech(00:09:20) - Sequel Med Tech data supports twiist automated insulin delivery in type 2 diabetes(00:11:18) - Dexcom study highlights benefits of G7 CGM in non-insulin type 2 diabetes(00:13:01) - Insulet data backs Omnipod 6, fully closed-loop AID systems(00:16:29) - FOMO Studio - Bill Frey, regional sales engineer, Harmonic Drive(00:27:14) - Keynote Interview - Darla Hutton, Global Vice President, Cardiac Surgery Intuitive

In this episode of the DeviceTalks Weekly Podcast, Host Tom Salemi interviews Lisa Earnhardt, Executive Vice President and Group, President, Medical Devices, Abbott. Earnhardt shared her views on Abbott’s advances in electrophysiology, pacemakers, and other technologies in this interview, which was conducted at DeviceTalks Minnesota. In our sponsor interview ATL Medical CEO Jim Fitzgerald unpacks the meaning of its Manufacturing for Life philosophy with Managing Editor Kayleen Brown. For more information go to www.ATLMedical.com. To find the blog mentioned in the interview, go here.  But we’ll start off with MassDevice Editor Chris Newmarker with this week’s Newsmakers – Philips, Disney, Neurovalens, Edwards, Insulet and Medtronic. *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:06:00) - Philips, Disney partner to improve MRI experience for children(00:09:40) - Neurovalens earns FDA nod for neuromod for PTSD(00:12:55) - Edwards gets FDA nod for Triformis Resilia surgical tricuspid valve replacement(00:14:22) - Insulet initiates another Omnipod 5 recall affecting 7 million devices including some Dash, Eros systems(00:17:01) - Medtronic sees best revenue growth in 10 years, but overall Q4 mixed(00:21:21) - Interview with ATL Medical CEO Jim Fitzgerald(00:29:37) - Keynote Interview - Lisa D. Earnhardt, Executive Vice President and Group, President, Medical Devices, Abbott

In this episode of OlympusTalks, host Tom Salemi is joined by Dr. Davinderbir Pannu, a gastroenterologist practicing at McLeod Health in South Carolina, and Amanda Call, Clinical Education Specialist at Olympus, for a conversation on how endoscopic imaging advancements support clinical decision-making during screening and therapeutic procedures. Together, they discuss real-world experiences using the EVIS X1™ endoscopy system and Extended Depth of Field (EDOF™) technology, with a focus on visualization, clinical efficiencies, and procedural confidence in both routine and advanced GI cases.  Chapter 1: Meet the Guests  Dr. Davinderbir Pannu discusses his career path into gastroenterology and advanced endoscopic procedures, including his current clinical practice.  Amanda Call shares her background as a registered nurse and her transition into clinical endoscopy support at Olympus.  Chapter 2: Clinical Challenges in GI Endoscopy  The importance of visualization in screening colonoscopy and advanced therapeutic procedures.   Common challenges related to movement, anatomy, and image clarity during endoscopic exams.  Chapter 3: Imaging Technologies in Practice  Overview of the EVIS X1™ endoscopy system, including TXI™ and RDI™ technologies.  How EDOF technology supports visualization during procedures.   Chapter 4: Supporting Screening and Therapeutic Procedures  Detecting flat and serrated polyps during screening exams.  Using imaging enhancements during procedures such as EMR, ESD, and third-space endoscopy.  Visualization considerations in inflammatory bowel disease and other GI conditions.   Chapter 5: Workflow, Ergonomics, and the Support Team  Ergonomic design considerations, including scope weight and button access.  Communicating scope and equipment needs across the endoscopy team to support efficient workflows.   For more episodes by OlympusTalks, please visit olympusamerica.com/podcasts.  This podcast has been paid for by Olympus Corporation of the Americas. The views and experiences shared are those of Dr. Davinderbir Pannu, a paid consultant of Olympus Corporation and its affiliates. Olympus makes no representations regarding the accuracy or applicability of the content and disclaims all liability arising from its use. Product performance may vary, and techniques, instruments, and clinical decisions are unique to each facility and practitioner. Always refer to the Instructions for Use (IFU) and applicable labeling for guidance, risks, and cautions.  ADDITIONAL RESOURCES:  Bring more into focus. Discover EDOF technology and how it may support your clinical practice: https://info.olympusamericamarketing.com/edof-technology Chapters (00:00:00) - Meet the Guests(00:09:03) - Clinical Challenges in GI Endoscopy(00:16:04) - Imaging Technologies in Practice(00:20:05) - Supporting Screening and Therapeutic Procedures(00:21:11) - Workflow, Ergonomics, and the Support Team

In this episode, the editorial team shares their highlights and lessons from two great days at DeviceTalks Boston. Tom Salemi, Kayleen Brown, Chris Newmarker, Jim Hammerand, Sean Whooley and Skyler Rivera highlighted discussions on new technologies, personal stories, Boston’s ecosystem, and the power of MedTech. Joining them on the panel were special guests Saul Marquez of the Outcomes Rocket, Etienne Nichols of Greenlight Guru and Holly Scott of The Mullings Group.  3:51 – Happy Birthday Kayleen Brown! 5:13 – MassDevice Executive Editor Chris Newmarker – Power of the Personal Story 9:25 - Senior Editor Sean Whooley – Analyzing Boston’s exceptionalism 11:10 -Associate Editor Skyler Rivera – Women in MedTech breakfast 14:05 – DeviceTalks Managing Editor Kayleen Brown -Designing for Reality/ Flipping the Script 17:28 - MDO Managing Editor Jim Hammerand – News Team Assembled! 20:10 – Saul Marquez, Outcomes Rocket – Importance of Conferences 24:16 – Etienne Nichols, Greenlight Guru – Why Making a Difference Matters 28:22 – Holly Scott, Senior Partner, The Mullings Group – Serendipity and MedTech Innovators 32:10 – Tom Salem – We Must Pay it Forward, New MedTech modalities *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:03:51) - Happy Birthday Kayleen Brown(00:05:13) - – MassDevice Executive Editor Chris Newmarker – Power of the Personal Story(00:09:25) - Senior Editor Sean Whooley – Analyzing Boston’s exceptionalism(00:11:10) - Associate Editor Skyler Rivera – Women in MedTech breakfast(00:14:05) - DeviceTalks Managing Editor Kayleen Brown -Designing for Reality/ Flipping the Script(00:17:28) - MDO Managing Editor Jim Hammerand – News Team Assembled!(00:20:10) - Saul Marquez, Outcomes Rocket – Importance of Conferences/Christian Howell(00:24:16) - Etienne Nichols, Greenlight Guru – Why Making a Difference Matters(00:28:22) - Holly Scott, Senior Partner, The Mullings Group – Serendipity and MedTech Innovators(00:32:10) - Tom Salemi - Pay It Forward, New MedTech Modalities

In this episode of DeviceTalks Weekly, Host Tom Salemi speaks with Axoft CEO and co-founder Paul Le Floch about the future of brain-computer interfaces and the material science breakthroughs powering the next generation of neural implants. Le Floch shares how his background in materials science led to the development of “Fleuron,” Axoft’s soft, flexible implant material designed to better match the brain’s delicate tissue and reduce long-term damage caused by traditional rigid implants. The conversation explores the challenges facing the BCI industry, including device durability, signal stability, and the difficulty of commercializing implantable neurotechnology. Le Floch also discusses Axoft’s focus on treating disorders of consciousness, its collaboration with Mass General Hospital, the company’s recent $55 million Series A financing, and why Massachusetts remains both an ideal — and expensive — place to build a deep-tech MedTech startup.  In our FOMO Studio, Salemi sits down with MassMEDIC President Brian Johnson and Holly Scott of The Mullings Group to preview DeviceTalks Boston and explore the state of the Massachusetts MedTech ecosystem. Johnson reflects on MassMEDIC’s 30th anniversary, the evolution of DeviceTalks, and why Massachusetts remains one of the world’s leading hubs for medical technology innovation. The conversation covers the region’s deep strengths in robotics, orthopedics, organ transplantation, and cardiovascular technology, along with the challenges startups face in securing early-stage funding and navigating tariffs and manufacturing shifts. And of course we start of with MassDevice Editor Chris Newmarker's top news from the pages of MassDevice - Cagent Vascular, BD, Medtronic, Johnson & Johnson MedTech, Endologix, Surmodics and Boston Scientific. Join us May 27-28th at DeviceTalks Boston. Visit Boston.DeviceTalks.com for the full agenda and speakers.  *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:04:41) - Cagent Vascular reports first-in-human IVL cases, closes $41M Series D(00:06:31) - BD taps former J&J leader as new president of Interventional(00:10:09) - Endologix acquires Pounce thrombectomy system from Surmodics(00:11:32) - Medtronic to acquire peripheral nerve stim developer SPR Therapeutics(00:13:30) - Boston Scientific invests $1.5B in TAVR developer MiRus, enters $2B share repurchase agreement

In this special episode of the DeviceTalks Women in MedTech podcast, Host Kayleen Brown brings listeners inside the 6th Women in MedTech Breakfast held May 4 at DeviceTalks Minnesota for a powerful keynote panel on “The Art of High-Stakes Decision-Making.” The conversation features Cat Jennings, SVP and President of Vascular Therapies at Boston Scientific; Laura Stoltenberg, President and CEO of Cryosa; and Marcie DeWalt, Chief Human Resources Officer at Provation. Together, they explore what it really takes to lead through uncertainty. From billion-dollar M&A and clinical trial bets to organizational transformations and personal career pivots, the panelists share candid stories about navigating moments where the pressure is real and the outcomes are uncertain. Throughout the discussion, the leaders examine the balance between data and intuition, the importance of stakeholder alignment, and how to develop the conviction to move forward when there is no "undo" button. Whether managing portfolio strategy at a strategic or navigating the growth of a startup, this episode offers practical frameworks for making decisions that shape companies, careers, and patient care. Kayleen also welcomes Heather Hudnut Page and Archana Desai in-studio to discuss the inspiration behind this year’s theme and how the Women in MedTech Breakfast continues creating space for authentic leadership conversations and community-building across the industry. Thank you to Aptyx for sponsoring the Women in MedTech Breakfast at DeviceTalks Minnesota and supporting these essential industry conversations!! Visit https://www.aptyx.com to learn more. Join us May 27-28th at DeviceTalks Boston for the next Women in MedTech Breakfast featuring Dr. Carla Goulart Peron, Chief Medical Officer for Philips to discuss designing MedTech for reality. https://boston.devicetalks.com/ *** Enjoy this podcast? Follow Women in MedTech with Kayleen Brown on all major podcast players: https://women-in-medtech.castos.com/subscribe + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:00:00) - Intro + DeviceTalks Boston 2026 preview(00:04:07) - In-studio guests: Heather Hudnut Page and Archana Desai(00:22:53) - Kayleen on Artemis II & High-Stakes Decision Making(00:25:40) - Keynote Panel: Cat Jennings, Laura Stoltenberg, and Marcie DeWalt(00:33:30) - M&A, Reorganizations, and Tough Business Decisions(00:50:00) - Clinical Trial Risks, Innovation Bets, and Portfolio Strategy(01:01:25) - Final Leadership Lessons: How Great Leaders Make High-Stakes Decisions(01:05:03) - Closing Remarks and Thank You to Aptyx

In this special DeviceTalks Weekly Podcast episode, Host Tom Salemi previews the biggest conversations, technologies, and innovators heading to DeviceTalks Boston on May 27–28 at the Boston Convention & Exhibition Center. First, Tom Salemi and Mike Moore, partner at The Mullings Group, visits with Christian Howell, CEO of Cognito Therapeutics. Howell will be speaking at DeviceTalks Boston about the neuro company’s clinical, fund-raising and partnering success. Howell also shares insights into Cognito’s partnerships with research institutions and the future of noninvasive therapies for neurodegenerative disease. He’ll be among the many speakers address Innovation & Investment at the conference, with others including the MedTech Innovator Open Rounds sessions and venture capital investors including Abby Hunter-Syed of Olympus Innovation Ventures and Maria Berkman, MD, of Vensana Capital. Tom and Holly Scott also speak with Dr. Sarah Matt, author of Borderless Healthcare Revolution, about the challenges of connected health adoption and why many health-tech pilots fail to scale. Matt previews her DeviceTalks Boston panel examining the “physician veto” and the barriers device makers face when introducing new digital health technologies into clinical environments. Several sessions at DeviceTalks Boston will address the challenges and opportunities of Connected Health including a keynote interview with Ashley McEvoy, CEO of Insulet, as well as presentations by Philips, Baxter and others. The episode also features a wide-ranging conversation with Mullings Group leaders Mike Moore and Holly Scott about the strength of the Massachusetts medtech ecosystem, the growth of surgical robotics, and the importance of conferences in building meaningful industry relationships. If you want to join us at DeviceTalks Boston, you can register at Boston.DeviceTalks.com. Use the code DTW25 to save 25% off the price of registration. *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:03:40) - Mike Moore of The Mulling Group and Tom interview Christian Howell, CEO of Cognito Therapeutics(00:15:40) - Holly Scott of the Mullings Group and Tom interview Sarah Matt, MD, author of The Borderless Healthcare Revolution(00:22:30) - Holly, Mike and Tom breakdown the components of DeviceTalks Boston and the Massachusetts MedTech industry

In this episode of DeviceTalks Weekly, Tom Salemi talks with Wayne Allen, the co-founder and CEO of Perfuze, an Irish company developing a novel new way of blood clot aspiration. Allen and his co-founder already executed one successful exit earlier in their careers. Can they find success again with Perfuze? This episode is sponsored by DeviceTalks Boston. Go to Boston.DeviceTalks.com to register. Use the code DTW25 to save 25%. MassDevice Editor Chris Newmarker opens up the podcast with this week’s top stories from the pages of MassDevice – Masimo, Danaher, ResMed, Johnson & Johnson MedTech, and Medtronic. *** Enjoy the show? Follow DeviceTalks Weekly on all major podcast players + Follow us on YouTube.com/@DeviceTalks to ensure you never miss an episode. Want access to the complete DeviceTalks Podcast Network (DTPN)? Follow us today at https://devicetalks.castos.com/subscribe Chapters (00:02:00) - Quick recap of DeviceTalks Minnesota(00:07:05) - MassDevice’s Orthopedic Device Companies Special Report for 2026(00:08:20) - Masimo shareholders give green light to $10B acquisition by Danaher(00:09:56) - ResMed enters merger agreement to acquire Noctrix Health for $340 million(00:14:03) - Johnson & Johnson says Ottava surgical robot met endpoints in pivotal bariatric surgery study(00:15:45) - Medtronic merges Cardiac Surgery, Aortic units into Cardiovascular Surgery business(00:19:45) - FOMO Studio – Yossi Bar, CEO, LEM Surgical(00:31:22) - Keynote Interview- Wayne Allen, CEO, Perfuze