Top 10 Most Downloaded Radiology Articles of 2025

Dr. Lauren Kim speaks with Adarsh Mallepady and Dr. Cory Trankle about their large-scale retrospective study of nearly 4 million patients examining the risk of nephrogenic systemic fibrosis after gadolinium-based contrast administration in those with advanced renal dysfunction. They discuss how modern group 2 and macrocyclic agents were associated with an exceedingly low incidence of NSF, offering important reassurance for evidence-based contrast use and evolving clinical practice. Nephrogenic Systemic Fibrosis in Patients with Advanced RenalDysfunction Following Gadolinium-based Contrast Agents. Mallepally et al. Radiology 2025; 317(3):e251794.   

Dr. Linda Chu speaks with Dr. Kavitha Chinnaiyan and Dr. Jonathon Leipsic about why 2026 marks an inflection point for coronary CT, from AI-enabled plaque quantification to FFR-CT and evolving guideline support for CT-first evaluation of suspected coronary artery disease. They explore how advanced imaging tools are reshaping risk assessment, personalizing prevention and revascularization decisions, and strengthening collaboration between radiology and cardiology while highlighting the need for validation, standardization, and equitable access.

Dr. Reni Butler speaks with Dr. Anne Marie McCarthy and Dr. Christine Edmonds about their study examining Black–White racial differences in background parenchymal enhancement (BPE) on contrast-enhanced breast MRI. They discuss the finding that black women had higher odds of high BPE independent of breast density, explore potential biologic and environmental drivers, and consider how quantitative BPE assessment could improve breast cancer risk stratification and screening equity. Black-White Racial Differences in Background Parenchymal Enhancement at Breast MRI. Mahmoud et al. Radiology 2026; 318(1):e251041.

Hosted by Dr. Lauren Kim, this episode explores the most downloaded Radiology article of 2025 with guests Dr. Carolyn Wang, Dr. Allison Ramsey, and Dr. David Lang, focusing on updated consensus guidance for managing hypersensitivity reactions to iodinated contrast media. The discussion highlights major changes in clinical practice, including more selective use of corticosteroid premedication and switching contrast agents when feasible to reduce the risk of recurrent reactions and standardize patient care. Management and Prevention of Hypersensitivity Reactions to Radiocontrast Media: A Consensus Statement from the American College of Radiology and the American Academy of Allergy, Asthma & Immunology. Wang et al. Radiology 2025; 315(2):e240100.

Dr Linda Chu and co-hosts Drs Refky Nicola, Lauren Kim, and Reni Butler look back on the Top 10 most downloaded Radiology articles of 2025, highlighting the studies and consensus statements that resonated most with readers worldwide. From breast imaging and AI to MR safety, contrast reactions, and beyond, this episode explores why these papers mattered and how they are shaping clinical practice. Top Publications in Radiology, 2025. Fowler and Goh. Radiology 2025; 317(3):e253887.

Radiology podcast host Dr Linda Chu and co-hosts Drs Celina Jo, Sid Dogra, Lauren Kim, and Refky Nicola look back at the most cited Radiology articles of 2025, highlighting the research that most influenced clinical practice and scientific discourse. The episode explores key advances across imaging modalities, AI, and emerging technologies, offering context on why these studies mattered and what they signal for the future of radiology. Top Publications in Radiology, 2025. Fowler and Goh. Radiology 2025; 317(3):e253887.

Dr. Linda Chu speaks with Dr. Suhny Abbara, the new Editor-in-Chief of Radiology, about his global journey in academic radiology and medical publishing. Dr. Abbara shares his vision for advancing imaging science, embracing innovation such as AI, and shaping the future of the journal to improve patient care.

Dr. Refky Nicola speaks with Dr. Sven Haller about the current clinical use of AI-accelerated MRI, exploring how these techniques improve scan speed, patient comfort, workflow efficiency, and image quality. They also examine key challenges including hallucinations, validation gaps, economic considerations, and the need for clear standards to guide safe and effective adoption. The Current Status of AI-accelerated MRI Techniques in Clinical Use. Haller et al. Radiology 2025; 317(2):e24381

This episode reviews recent evidence on microwave and radiofrequency ablation as minimally invasive treatments for primary and secondary hyperparathyroidism, highlighting efficacy, safety, and complication profiles compared with surgery. Focusing on a multicenter prospective Radiology study in older patients, the discussion shows that both ablation techniques achieve meaningful biochemical improvement with acceptable risk, particularly as alternatives for patients who may not be ideal surgical candidates. Efficacy and Safety of Microwave and Radiofrequency Ablationin the Treatment of Hyperparathyroidism in Older Individuals:A Multicenter Prospective Study. Zhang and Liu et al. Radiology 2025; 317(1):e243359. 

Dr. Lauren Kim speaks with Dr. Ritu Gill, Professor of Radiology at Columbia University, about the updated ninth edition TNM staging system for pleural mesothelioma, including the new metrics used to quantify pleural tumor in CT imaging. ARTICLE LINKS:Editorial: https://pubs.rsna.org/doi/10.1148/radiol.252343 Review: https://pubs.rsna.org/doi/10.1148/radiol.250531