Medicus Pharma and HelixNano sign MOU to co-develop thermostable, needle-free mRNA vaccines

Alvopetro Energy CEO Corey Ruttan talked with Proactive's Stephen Gunnion about the company’s strong second-quarter performance, highlighting key production and operational progress in both Brazil and Western Canada. Alvopetro Energy reported average production of 2,436 barrels of oil equivalent per day in Q2 2025, up 50% from the same period last year. The quarter marked the first full quarter to include production from its newly acquired Western Canadian assets, which contributed 138 barrels per day. This helped generate funds from operations totalling US$10.4 million. Ruttan said the Western Canada assets complement the company’s disciplined capital allocation strategy. "These initial two earning wells... are certainly exceeding expectations," he noted. Alvopetro is using open-hole multi-lateral technology in Canada, with two recent wells providing over 19km of reservoir access. In Brazil, drilling continues at both the Caburé and Murucututu fields. At Caburé, three wells are completed, with a fourth underway and all set to come online shortly. At Murucututu, a seven-zone completion was recently finished, with production expected soon. Ruttan also addressed gas pricing stability under Brazil’s long-term contracts, noting operating netbacks of nearly US$55 per BOE and an 87% profit margin. For more interviews like this, visit Proactive’s YouTube channel. Don’t forget to like this video, subscribe, and turn on notifications for the latest updates. #AlvopetroEnergy #CoreyRuttan #OilAndGas #BrazilEnergy #WesternCanadaOil #Q2Earnings #EnergyStocks #NaturalGas #ResourceSector #MultilateralDrilling #ProductionGrowth #DividendStocks #CashFlow #InvestorUpdate

Nextech3D.ai CEO Evan Gappelberg talked with Proactive's Stephen Gunnion about the company's latest breakthrough in AI-powered 3D model production. The company has announced a major scalability enhancement, enabling the generation of 100 3D models simultaneously—up from just one—through its AI production engine. Gappelberg described the change as “a quantum leap in terms of productivity,” highlighting that it is not just an efficiency upgrade but a structural transformation of the company’s operations. This advancement significantly boosts Nextech3D.ai’s ability to deliver high-volume output to global e-commerce and enterprise clients. He noted that a large contract already in production is benefiting from faster turnaround times and improved throughput. “Most of the production now is being done by AI,” Gappelberg stated, emphasizing that the automation has helped reduce manual overhead and improve margins. The company expects this development to be the foundation for future scaling, with potential to expand to 500 or even 1,000 models in parallel. Gappelberg also reported that 2024 figures showed a 50% reduction in operating costs, validating their AI roadmap. This milestone positions Nextech3D.ai to serve a rapidly growing need for 3D content in online retail, as demand for digital twins accelerates. Watch more interviews on Proactive’s YouTube channel. Don’t forget to like this video, subscribe to our channel, and enable notifications so you never miss an update.** #Nextech3D #ArtificialIntelligence #3DModeling #EcommerceTech #DigitalTwins #AIInnovation #Scalability #TechNews #ProactiveInvestors #RetailTech #AIAutomation

Foresight Solar Fund Ltd's Toby Virno talked with Proactive's Stephen Gunnion about the company’s second-quarter net asset value (NAV) update and wider performance indicators for 2025. The fund reported a NAV of £603.8 million, equivalent to 108.5 pence per share. Virno noted that the company benefited from high levels of solar irradiation across the UK, contributing to a strong operational performance. “We’ve had plenty of sunshine in the UK… [electricity production was] 4% above budget,” he said. Despite a reduction in NAV driven by lower UK power price forecasts, cash flow remains resilient, and the company is on track to meet its dividend targets. The board has reaffirmed a 1.3x dividend cover target for the year. Virno also highlighted ongoing debt reduction efforts and the continuation of a substantial share buyback program, with an additional £10 million allocated. “This buyback program remains one of the largest in the sector relative to the fund size,” he explained. A major forward-looking highlight includes the announcement of 100MW in new battery storage capacity in Spain, advancing the company’s development pipeline. One solar project in Spain is expected to become fully committed later this year, marking another key milestone. To hear more insights like this, visit Proactive’s YouTube channel. Don’t forget to like the video, subscribe to the channel, and enable notifications for future content. #ForesightSolar #RenewableEnergy #SolarPower #GreenInvesting #BatteryStorage #DividendStocks #SustainableEnergy #ShareBuyback #CleanEnergyInvesting #TobyVirno #EnergyTransition #UKSolar #ESGInvesting

North Bay Resources Inc CEO Jared Lazerson talked with Proactive's Stephen Gunnion about the company’s progress at its Fran project, including high-grade assay results and operational plans for its Bishop Gold Mill. Lazerson confirmed that North Bay has completed its initial test mining and is seeing encouraging assay results from the surface oxide zone at Fran. “There have been up to multi-ounce assays,” he said, noting that the mineralization appears to expand in several directions and increases with depth. The ore is described as highly mineralized and visibly distinct, with chalcopyrite, galena, and silver present. Lazerson highlighted that operations are already producing results: “Our mill is up and running. We've produced some gold there.” He outlined plans to ship ore to the mill imminently, targeting an initial throughput of 66 tonnes per week, with potential gross revenues of around $75,000 weekly. Costs are currently about $400 per tonne, giving an estimated $600 profit per tonne after refining. Longer term, the company is targeting a 10,000-tonne test permit and evaluating the path toward a large-scale operation. Lazerson said the broader resource could support a 1 million to 2 million tonne processing capacity. The aim is to become a mid-tier producer, with the potential to generate between $50 million and $100 million, depending on gold prices and comparable mine costs. The company is pursuing a dual-path strategy—short-term cash flow from high-grade ore while advancing toward large-scale development. Lazerson emphasized this approach helps avoid “endless dilution,” a risk many early-stage explorers face. Visit Proactive’s YouTube channel for more videos, and don’t forget to give this one a like, subscribe to the channel, and enable notifications for future content. #GoldMining #NorthBayResources #FranProject #JaredLazerson #GoldAssays #MiningStocks #BishopGoldMill #JuniorMining #PreciousMetals #MiningInvestment

Seeing Machines Ltd (AIM:SEE, OTC:SEEMF) CEO Paul McGlone talked with Proactive's Stephen Gunnion about the company’s recent fourth-quarter KPIs and ongoing progress towards cash flow breakeven and profitability. McGlone said Seeing Machines had significantly reduced costs by over $1 million per month, a key milestone already flowing through to the company’s accounts and growth plans. He highlighted a “dramatic recovery” in automotive royalties, with Q4 showing 36% quarter-on-quarter growth. McGlone added, “If that growth rate just maintains at, say, 20% for the next two quarters, we’ll be right in the middle of our $700,000 to $750,000 range per quarter.” The CEO also shared positive developments in aftermarket demand for Guardian Generation 3, noting strong uptake across EMEA, the Americas, and Asia-Pacific. The company delivered more than 2,500 Gen 3 units in the quarter, and is targeting between 6,000 and 6,500 units per quarter by year-end. McGlone explained that sales momentum is underpinned by regulatory drivers such as the upcoming General Safety Regulation (GSR) in Europe, as well as an active RFQ pipeline and trials with around 20 new customers globally. On the automotive side, while RFQ closures have been delayed due to the European summer, McGlone said, “The RFQ pipeline is actually really strong,” adding that all current programs are hitting start-of-production timelines. He reaffirmed the company’s two strategic focus areas: growth in royalties and Gen 3 unit sales. With GSR set to drive significant royalty expansion through to July 2026, McGlone expressed confidence in the company’s growth trajectory. Visit Proactive’s YouTube channel for more videos, and don’t forget to give the video a like, subscribe to the channel and enable notifications for future content. #SeeingMachines #PaulMcGlone #GuardianGen3 #AutomotiveTechnology #DriverMonitoring #FleetSafety #CostReduction #Profitability2025 #GSR #VehicleSafety #AftermarketSales #Autotech #RFQs #ProactiveInvestors

Kodal Minerals PLC (AIM:KOD) CEO Bernard Aylward talked with Proactive's Stephen Gunnion about the latest developments at the Bougouni Lithium Project in Mali. The update follows a high-profile site visit by Mali’s Minister of Mines and the regional governor, underlining government support for the project. Aylward said the visit reaffirmed the importance of Bougouni for both the local community and Mali’s broader mining ambitions. “The Minister of Mines had actually met with the president, discussed our situation, and came back to remark that a fast-track process was in place,” he said. Kodal has completed all required demonstrations to government officials, including operational success at the processing plant and the accumulation of 42,000 tonnes of spodumene ready for export. Aylward noted the urgency of securing the export licence, as storage space is now limited. He also provided an update on site activities, confirming that despite the wet season causing some flooding and delays, mining is continuing. The company is addressing a temporary shortage of explosives due to regulatory changes, while also progressing workforce development by training local staff to operate the plant. Kodal Minerals expects to report back soon with updates on the export permit and continued ramp-up. For more updates like this, visit Proactive’s YouTube channel. Don’t forget to like the video, subscribe to the channel, and turn on notifications so you never miss future content. #KodalMinerals #LithiumMining #BougouniProject #MaliMining #Spodumene #BatteryMetals #MiningUpdate #ResourceStocks #JuniorMining #ProactiveInvestors

Arizona Gold and Silver CEO Mike Stark joined Steve Darling from Proactive to share positive results from the company’s ongoing core drilling program at the Philadelphia Project in Arizona. The latest highlight comes from core hole PC25-155, which returned 14.5 g/t gold over 1.52 meters, within a broader interval of 4.24 g/t over 22.26 meters, underscoring both vein continuity and increasing grade at depth. Stark noted that this new intercept comes from a single massive composite and brecciated quartz vein and marks a 40% increase in grade compared to hole PC25-154, located about 60 meters up dip. Both holes intersected similar drill thicknesses, with true thickness of PC25-155 estimated at approximately 57% of the drilled interval. Drilling is continuing with core hole PC25-156, which is currently at a depth of 872 feet (265.85 meters) and approaching the top of the targeted vein within roughly 200 feet (60.98 meters). Stark emphasized the importance of this hole in guiding the next phase of drilling, which will likely expand strike length in both directions, further enlarging the mineralized footprint. #proactiveinvestors #arizonagoldandsilverinc #tsxv #azs #otcqb #azasf #GoldExploration #PhiladelphiaProject #MiningNews #JuniorMining #HeapLeach #Metallurgy #ResourceInvesting #GoldStocks #PreciousMetals #MiningNews #GoldExploration #SilverMining #JuniorMining #ArizonaMining #GoldInvesting #DrillResults #MiningInfrastructure #ProactiveInvestors #perryzone #risingfawnzone

Medicus Pharma CEO Dr Raza Bokhari joined Steve Darling from Proactive to announce the signing of a non-binding Memorandum of Understanding (MoU) with biotechnology firm HelixNano, aimed at co-developing thermostable mRNA-based vaccines by combining their respective proprietary technologies. The collaboration intends to merge HelixNano’s advanced mRNA vaccine platform with Medicus’ dissolvable microneedle array (MNA) delivery system, with the goal of creating needle-free, thermostable vaccines that can overcome cold-chain logistics, reduce distribution costs, and significantly enhance global accessibility. Dr. Bokhari noted that both companies are in active negotiations to form a joint venture that will lead the co-development and commercialization of these next-generation vaccines. As part of the preliminary work, Medicus and HelixNano have agreed to begin research and production of clinical-grade mRNA vaccine-loaded MNAs for use in a Phase 1 clinical bridging study. This study will compare the safety and early efficacy of traditional intramuscular injection versus intradermal microneedle delivery using HelixNano’s HN-0001 vaccine candidate. Bokhari stated, “Combining HelixNano’s potent mRNA vaccine science with our dissolvable microneedle array technology has the potential to redefine how vaccines are delivered worldwide—without needles, without refrigeration, and at scale. This could place us at the forefront of a paradigm shift in infectious disease prevention.” The MoU formalizes the mutual intent to collaborate while both parties work to finalize the terms of the proposed joint venture. #proactiveinvestors #nasdaq #mdcx #tsxv #mdcx #pharma #Biotech #CancerTreatment #ClinicalTrials #FDAApproval #SkinCancer #HealthcareInnovation #Investing #MedicalResearch #SkinCancer #BasalCellCarcinoma #BiotechNews #CancerResearch #UAEHealth #NonInvasiveTherapy #Doxorubicin #ClinicalTrials #HealthcareInnovation

Reconnaissance Energy Africa or ReconAfrica CEO Brian Reinsborough joined Steve Darling from Proactive to announce that the Kavango West 1X exploration well was officially spud on July 31st. The well is expected to reach a total depth of approximately 3,800 metres by the end of November 2025, targeting over 1,500 metres of Otavi carbonate reservoir, which is the primary objective of the Damara Fold Belt play. Reinsborough explained that Kavango West 1X is a large structural fold identified on modern 2D seismic data, measuring approximately 22 kilometers long by 3 kilometers wide. The well was reprioritized over other planned locations following the results of the company’s previous well, Naingopo. This strategic shift, although extending the timeline slightly, reflects ReconAfrica’s emphasis on rigorous technical analysis to maximize the potential for commercial success. The company says this location represents its best opportunity in the Damara Fold Belt to unlock the full potential of this play. The company is looking to share results before the end of 2025. ReconAfrica has identified over 19 prospects and four leads in the Damara Fold Belt trend and recently secured an additional 5 million acres via a Memorandum of Understanding in neighboring Angola. Due to current drilling priorities, the previously announced 3D seismic program has been rescheduled for 2026. Meanwhile, the company continues to evaluate strategic investment opportunities, including additional acreage, joint ventures, and production asset acquisitions, in line with its goal to accelerate production and cash flow generation. #proactiveinvestors #reconnaissanceenergyafricaltd #tsxv #reco #otcqx #recaf #NamibiaOil #ProspectI #OilExploration #EnergyUpdate #OnshoreDrilling #OilAndGasNews #AfricanEnergy #OilDiscovery #EnergyInvesting #OilExploration #NamibiaOil #KavangoWell #OilExploration #EnergyNews #OnshoreDrilling #OilAndGas #BrianReinsborough #ProactiveInvestors #EnergyAfrica

Digitalbox PLC CEO James Carter talked with Proactive about the company’s strong first-half performance in a challenging advertising environment and outlined recent strategic developments. Carter began by noting the broader difficulties in the advertising sector but emphasised that Digitalbox was "bucking the trend" with year-on-year growth. He confirmed that a strategic review carried out at the end of last year had guided the company’s current plan, which was announced in March, focusing on expanding its existing model through new launches and acquisitions. In the first half of the year, Digitalbox launched three new web brands: Royal Insider, Reality Shrine, and EastEnders Insider, bringing the company’s portfolio to eight products. The company also completed the acquisition of three Facebook pages, including The Life Network (with 5.5 million followers), Funny Cards Against Humanity, and British Banter, which have been integrated with Digitalbox's brands. Carter also addressed concerns around changing search engine dynamics and AI-driven results, stating that despite those headwinds, “our audience development has been really exactly where we budgeted.” Digitalbox expects 11% revenue growth, with some brand performances up as much as 130% year-on-year in certain months. Carter attributed the gains to stronger programmatic advertising returns and diversification efforts, especially in on-platform monetisation. Looking ahead, the company plans further diversification, including exploring direct email opportunities and potential new acquisitions. For more interviews like this, visit Proactive’s YouTube channel. Don’t forget to like this video, subscribe, and enable notifications for future content. #Digitalbox #MediaGrowth #AdvertisingMarket #JamesCarter #OnlineMedia #RevenueGrowth #DigitalAdvertising #FacebookAcquisition #ProactiveInvestors #MediaDiversification