Lisata Therapeutics and GATC Health see collaboration as the way forward for drug development

Lisata Therapeutics Inc CEO Dr David Mazzo and GATC Health chief business officer Tyrone Lam talked with Proactive's Stephen Gunnion about the companies' collaboration to advance a novel treatment for opioid use disorder. Mazzo explained that combining Lisata’s regulatory and clinical expertise with GATC’s MAT artificial intelligence platform allows the team to significantly reduce the trial-and-error typical in early drug development. “The reason that we've expanded the partnership is that we see a real symbiotic relationship between the two organizations,” Mazzo said. He highlighted that the AI platform has enabled the identification of promising candidates much faster than conventional approaches. This first program targets opioid abuse, which Mazzo described as a large unmet medical need and a significant social issue in the United States. He noted the market potential could be valued in the billions of dollars, creating both commercial and social opportunities. Mazzo also discussed how the partnership model could lead to either independent commercialization or licensing deals with larger pharmaceutical companies. Throughout the discussion, both Mazzo and Lam emphasized that the combination of AI and biotech expertise may serve as a model for future drug development collaborations. Visit Proactive’s YouTube channel for more videos. Don’t forget to give this video a like, subscribe to the channel, and enable notifications for future content. #LisataTherapeutics #GATCHealth #OpioidCrisis #DrugDiscovery #ArtificialIntelligence #BiotechInnovation #MATPlatform #OpioidUseDisorder #ClinicalTrials #NonOpioidTreatment

Manx Financial Group (AIM:MFX) CEO Douglas Grant talked with Proactive about the company’s record 2024 results and plans for continued expansion. Grant shared that Manx Financial Group delivered a 41% jump in profits last year, driven by three main growth areas: Conister Bank’s strong liquidity, Payment Assist’s accelerating lending volumes, and Manx Ventures’ strategic investments. He explained, “Buy now, pay later allows people to spread the unexpected bill… but it’s interest-free, so it’s actually not costing the consumer anything.” The company has seen Payment Assist grow lending from £180 million to over £220 million in a year. Grant also discussed the move into mortgages and plans to enter the Irish market by securing a consumer credit license. He said this expansion would enable Manx Financial Group to passport operations across the EU, creating further growth potential. Regarding shareholder returns, Grant highlighted the consistent approach of paying 10% of profits as dividends while reinvesting capital to fuel the company’s growth strategy. In 2025, he said the acquisition of a wealth management firm and the launch of Buy Now Pay Later Ltd and Drive Now Pay Later in Ireland are expected to drive further momentum. Visit Proactive’s YouTube channel for more interviews like this. Don’t forget to like this video, subscribe, and turn on notifications for the latest updates. #ManxFinancialGroup #DouglasGrant #BuyNowPayLater #FinancialResults #DividendGrowth #IrishMarketExpansion #PaymentAssist #ConisterBank #InvestorUpdates #ProactiveInvestors

London BTC Company Ltd (LSE:BTC, OTCQB:VINZF) CEO Hewie Rattray talked with Proactive's Stephen Gunnion about the company’s £1.5 million capital raise and how it plans to deploy these funds to build its Bitcoin holdings. Rattray explained that nearly all of the capital will be used to increase the company’s Bitcoin stack over the next six to twelve months. Rattray also discussed how the firm is exploring more dilutive and non-dilutive forms of financing, including convertible debt with long-dated conversion options. He noted there is investor appetite for treasury-focused strategies. However, part of the effort involves educating institutional investors about the company’s model and how its approach can offer a more dynamic exposure to Bitcoin. While Rattray continues to recommend that investors consider owning Bitcoin directly, he highlighted that treasury companies provide what he called “something slightly more leveraged to the upside.” Addressing recent shareholder concerns about the capital raise, Rattray emphasised the focus on long-term outcomes and making decisions that may be unpopular in the short term but are intended to benefit investors over time. He said the company would keep building its Bitcoin stack in all market conditions while exploring options to reduce dilution. Visit Proactive’s YouTube channel for more interviews and insights, and don’t forget to give this video a like, subscribe to the channel, and enable notifications so you never miss an update. #Bitcoin #CryptoTreasury #HewieRattray #LondonBitcoinCompany #BitcoinInvestment #CryptoStrategy #ProactiveInvestors #BitcoinBullMarket #BitcoinTreasuryCompany #CryptoCapitalRaise

Chesnara PLC (LSE:CSN) chief executive Steve Murray talked with Proactive's Stephen Gunnion about the company’s £260 million agreement to acquire HSBC Life UK’s insurance business. The deal, set to complete in early 2026, will see over 450,000 policyholders join Chesnara and bring approximately £4 billion of assets under administration. Murray said, “We’re really proud to have been selected by HSBC Group to look after over 450,000 of their policyholders.” The acquisition is expected to deliver strong cash generation, with over £800 million of incremental cash flows forecast across the life of the book. About £140 million is anticipated in the first five years, with the majority accruing in the longer term. The company told investors that the acquisition will also accelerate its dividend growth by one year, resulting in a 6% increase applicable to full-year 2025 and interim 2026 dividends. Financing will include a fully underwritten rights issue of £140 million gross and the drawdown of £65 million from an existing revolving credit facility. Murray highlighted that this transaction more than doubles the scale of Chesnara’s UK business and demonstrates its ability to be a reliable consolidator in the life insurance sector. He said the company continues to see a strong M&A pipeline, with further opportunities under review. Visit Proactive’s YouTube channel for more insightful interviews and don’t forget to like this video, subscribe to our channel, and enable notifications so you never miss an update.#Chesnara #HSBCLifeUK #InsuranceAcquisition #LifeInsurance #DividendGrowth #MergersAndAcquisitions #UKInsuranceMarket #Policyholders #FinancialNews #ProactiveInvestors

Fineqia International Inc (CSE:FNQ, OTC:FNQQF) CEO Bundeep Singh Rangar talked with Proactive about the strong early traction of the Fineqia Bitcoin Yield ETP (YBTC). YBTC has quickly surpassed C$15 million in assets under management, driven by what Rangar described as a “triangulation” of factors: high demand for bitcoin, Europe’s regulatory framework enabling yield generation from on-chain activities, and growing institutional appetite for passive income products. He explained, “We can actually give you the full upside, and we will also give you yield on that that we think is going to generate consistent yield regardless of price movement at that sort of 6% rate.” According to Rangar, YBTC is unique because it sources yield from DeFi lending and liquidity provisioning without capping bitcoin’s price appreciation. Rangar also outlined how Fineqia mitigates counterparty risk by partnering with established DeFi protocols and working alongside Psalion, a firm with experience managing these strategies. He noted that Europe remains the leading market for crypto-based ETFs and ETPs, with about 60% of such products globally based in the region. Looking ahead, Fineqia is exploring additional exchange listings, including Euronext, and evaluating the potential to launch similar yield-focused products for other digital assets. Rangar emphasised that the combination of regulated access, DeFi yield, and full bitcoin exposure sets YBTC apart from traditional trackers and covered call strategies. Visit Proactive’s YouTube channel for more insightful interviews. Don’t forget to give this video a like, subscribe to the channel, and enable notifications for future content. #FineqiaInternational #YBTC #BitcoinYield #DeFiInvesting #CryptoETFs #DigitalAssets #BitcoinETF #PassiveIncome #InstitutionalCrypto #ProactiveInvestors #BTC #CryptocurrencyInvesting

Savannah Resources PLC (AIM:SAV, ETR:SAV, OTC:SAVNF) CEO Emanuel Proença talked with Proactive's Stephen Gunnion about the company’s progress at its Barroso Lithium Project in northern Portugal. Savannah Resources is a junior miner fully permitted to develop a lithium spodumene resource that Proença described as “the only sizable and competitive resource in Europe.” During the interview, Proença detailed how the recent £4.8 million fundraise, which included an accelerated bookbuild and retail offer, brought more Portuguese shareholders on board. “More than 40% of the subscription was subscribed by Portuguese shareholders,” he noted. Proença explained that Savannah had already secured most of the funding for its Definitive Feasibility Study through a strategic partnership with AMG Critical Materials. The new funds will prepare Savannah for subsequent steps, including front-end engineering and project financing. He also emphasised that the project is on track to start production between late 2027 and early 2028, positioning Savannah to support Europe’s push to localise the battery value chain. Proença highlighted that in Europe, only Savannah and Keliber in Finland are advancing spodumene projects to this stage. The CEO underscored that Savannah’s work engaging transparently with local communities has helped build support and momentum. “It is very good to see that what we are doing in terms of getting closer to the local population is paying off,” he said. Visit Proactive’s YouTube channel for more interviews and updates. Don’t forget to give this video a like, subscribe to the channel, and enable notifications for future content. #SavannahResources #LithiumMining #PortugalLithium #BarrosoProject #BatteryMetals #CriticalMinerals #EuropeanMining #LithiumSupplyChain #JuniorMiners #AIMListed #MiningInvesting

Georgina Energy PLC (LSE:GEX) chief financial officer Mark Wallace talked with Proactive's Stephen Gunnion about the company’s recent financial results delay and its strategic plans for natural gas development. Wallace explained that the delay was due to the complex reverse takeover of Mining, Minerals & Metals PLC and the subsequent re-listing process, which involved multiple moving parts for the auditors to review. "My thanks go out to my team. They’ve only been with Georgina for six months, and within that time, we had to put the accounts into a new accounting system," Wallace said. He confirmed that although the accounts were released four weeks later than expected, they were accurate and complete. Wallace noted that the audit process will be smoother going forward as Georgina Energy has streamlined its systems. He stressed that the delay did not impact operational activities, with engagement continuing uninterrupted with both the Department of Energy and Minerals and indigenous partners on the Hussar and Mt Winter sites. Looking ahead, Wallace highlighted the company’s confidence in the long-term demand for natural gas as an enabler of energy transition. He said formal drilling approval for Hussar is expected soon and the Aboriginal land rights agreement for Mt Winter is close to completion. Georgina Energy is also in discussions with offtake partners, having signed one memorandum of understanding already. Visit Proactive’s YouTube channel for more interviews and updates. Don’t forget to like this video, subscribe to the channel, and enable notifications for future content. #GeorginaEnergy #NaturalGasAustralia #EnergyTransition #GasExploration #MarkWallace #HussarProject #MtWinterProject #ASXUpdates #InvestorNews #ResourceDevelopment

Oriole Resources PLC CEO Martin Rosser talked with Proactive's Stephen Gunnion about the company's announcement of a significant maiden exploration target at its Mbe project in Cameroon. The milestone was achieved in under nine months from the start of the maiden drilling. Rosser explained that the independent consultant Forge estimated a median tonnage of 38 million tonnes at a mean grade of 0.86 grammes per tonne gold. This includes a mid-range level of 1.10 million ounces of contained gold. Rosser stated, "As soon as you get over 1,000,000oz, you are really motoring," underscoring the importance of this figure. The target model is limited to 200 metres below surface and is based on 2024 trenching data and assays from 13 of 24 planned drill holes at Mbe South. He added that grade tonnage sensitivity analysis showed strong retention of contained ounces at higher cut-off grades. The project shares mineralogy similarities with the Bibemi project and is considered suitable for open-pit mining methods. Rosser also noted that drilling at Mbe South continues and the company expects to deliver a maiden pit-constrained Mineral Resource estimate in the fourth quarter of this year. He emphasised the potential across the broader Mbe licence area and the company's surrounding eastern CLP licences in Cameroon. Visit Proactive’s YouTube channel for more videos like this. Don’t forget to give this video a like, subscribe to the channel, and enable notifications so you never miss an update. #OrioleResources #CameroonGold #MbeProject #GoldExploration #MiningNews #JuniorMining #AfricanMining #GoldDiscovery #ResourceEstimate #ProactiveInvestors

Ocean Power Technologies CEO Philipp Stratmann joined Steve Darling from Proactive to announce the successful deployment of the company’s PowerBuoy® system in Monterey Bay, California, in support of the Naval Postgraduate School. This latest installation is part of a previously announced contract and represents a strategic leap forward in integrating renewable offshore energy with advanced communications and sensor capabilities. Stratmann emphasized that the system will deliver autonomous, persistent offshore monitoring in one of the most strategically significant marine environments on the U.S. West Coast. The PowerBuoy® is configured to accommodate additional environmental and research sensors from NPS and potential collaborators, supporting a wide range of defense, security, and scientific objectives. This deployment represents a milestone in OPT’s strategic roadmap, demonstrating how its technology can serve as a multi-mission platform—generating clean power, enabling real-time communications, and supporting AI-driven maritime operations for both manned and unmanned systems. Stratmann also underscored the broader potential of PowerBuoy® as a 5G communications node, enabling coastal and offshore connectivity infrastructure that enhances operational awareness and data transmission capabilities for U.S. defense and research entities. This high-impact project positions Ocean Power Technologies as a critical enabler of smart ocean infrastructure, paving the way for scalable deployments in maritime security, environmental monitoring, and sovereign defense networks. #proactiveinvestors #oceanpowertechnologiesinc #nyseamerican #optt #PhillipStratmann, #USGovernmentContract, #OffshoreAutonomy, #MaritimeSecurity, #CommercialPlatforms, #GrowthStrategy, #BuoyBusiness, #VehicleBusiness, #InternationalExpansion, #ReadyToDeploy #AutonomousVehicles #MaritimeTech #CleanEnergySolutions #AUVSI #SustainableTechnology #MarineInnovation #EnergyEfficiency #UncrewedSystems #GlobalExpansion

Arizona Gold and Silver CEO Mike Stark joined Steve Darling from Proactive to announce a notable high-grade vein intercept from the company’s ongoing drill program at the Philadelphia Project in Arizona. Drill hole PC25-154, located in the Perry Zone, intersected 22.47 metres grading 3.05 grams per tonne (g/t) gold, including 1.59 metres grading 11.5 g/t gold and 3.69 metres grading 6.41 g/t gold. Stark highlighted that the high-grade intervals are associated with zones of yellow quartz within a classic epithermal quartz and bladed calcite-bearing vein system. The presence of yellow quartz, a known indicator of high-grade mineralization across the district, reinforces the geological model that gold grades increase with depth at the Philadelphia Project. The Perry Vein, which yielded these intercepts, is a distinct and separate structure from the Rising Fawn Zone, situated just 30–60 metres away across a drainage. While Rising Fawn has been the focus of earlier drilling, attention has now shifted to testing down-dip extensions of mineralization in the Perry Vein, based on these promising results. Drilling at the Perry Zone is ongoing, while drilling at Rising Fawn has been paused pending assay results. Notably, the assays for hole PC25-154 were rushed due to the strong visual indicators, temporarily delaying results for previously submitted holes. These results continue to build momentum for Arizona Gold & Silver’s expansion strategy at Philadelphia, supporting the potential for a robust, multi-zone high-grade gold system across the project’s strike and depth. #proactiveinvestors #arizonagoldandsilverinc #tsxv #azs #otcqb #azasf #GoldExploration #PhiladelphiaProject #MiningNews #JuniorMining #HeapLeach #Metallurgy #ResourceInvesting #GoldStocks #PreciousMetals #MiningNews #GoldExploration #SilverMining #JuniorMining #ArizonaMining #GoldInvesting #DrillResults #MiningInfrastructure #ProactiveInvestors #perryzone #risingfawnzone