Episode 357: CDP Choline for Brain Performance with Katie Emerson

Welcome back to the Flex Diet Podcast! Today, I’m hanging out with the brilliant Katie Emerson, Senior Manager of Scientific Affairs over at Kyowa Hakko USA, aka the people behind Cognizin (CDP Choline), one of the few brain-boosting ingredients with legit research behind it.We dig into the real science of CDP Choline, how it supports memory, focus, and cognitive performance, and where it actually fits into the human physiology engine, not the hype machine. Katie and I also zoom out into the supplement industry as a whole, chatting about what’s worth paying attention to, what’s still emerging, and how to navigate all the shiny promises out there.We even take a nerd-tour into mental resilience, genetic mapping, and the surprising potential of glutathione for health and performance.If you’re curious how targeted supplements can help you think faster, recover better, and be a more high-performing human without needing a PhD to decode marketing nonsense, this episode is for you.Sponsors:Flex 4: Katie's top 4 things to know about citocholineEpisode Chapters:03:52 Katie Emerson Joins the Conversation04:09 Conversations at ISSN and Networking11:20 Research and Studies on CDP Choline17:49 Challenges in Supplement Formulation24:40 Mechanisms and Benefits of CDP Choline28:06 Exploring Genetic Mapping and Data Overload29:01 Study Design and Dosing Strategies30:29 The Sweet Spot of CDP Choline Dosage33:40 Pharmacokinetics and Timing of CDP Choline35:36 Safety and Side Effects of High Doses38:59 Comparing CDP Choline and Alpha GPC42:41 Introduction to Glutathione48:41 Oral Absorption of Glutathione52:12 Podcast Conclusion and Listener Information Episodes You Might Enjoy:Episode 343: Fueling the Corporate Athlete: Stress, Supplements & Performance with Dan Hunter YouTube: https://youtu.be/0ek4XSs62RQ Episode 222: Expert Insights on nutrition, supplements, and training with Registered Dietitian Sean CaseyYouTube: https://youtu.be/wjJB-y1kwgMConnect with Katie:Cognizin: cognizin.comGet In Touch:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/

On this episode of the Flex Diet Podcast, I sit down with my good buddy and lab-coat-wearing performance wizard, Dr. Andrew Koutnik. We talk about how to boost muscle performance, improve body composition, and feel like an athletic human without dumpster-firing your health.We dig into cold water immersion (and when it can kick gains in the shins), blood glucose regulation, ketogenic diets, carbs (yes, they’re still awesome), and how to build metabolic flexibility that actually translates to better outcomes in the gym and life.Andrew shares some killer insights from his research at Florida State University, especially around keto diets and athletic performance. If you’re curious about whether low-carb can help or hurt your performance, this is your jam.If you want practical tools for a bigger physiological engine, tune in!Sponsors:Tecton Ketones: https://tectonketones.com/LMNT:  http://drinklmnt.com/mikenelson (automatically applied at Episode Chapters:05:28 Conferences and Networking08:34 The Importance of Practical Application in Science21:43 Cold Water Immersion and Stress Responses32:53 Mindfulness and Meditation39:29 Blood Glucose and Exercise Performance52:00 Limitations of Association Studies in Sports Performance52:47 Impact of Blood Glucose on Performance57:04 Historical Perspective on Ketogenic Diets01:00:52 Study on Ketogenic Diets and Ironman Competitors01:15:53 Health Implications of High Carbohydrate Diets01:18:48 Concluding Thoughts on Nutrition and Performance Episodes You Might Enjoy:Episode 254: Exploring the Frontiers of Ketone Science and Brain Health with Mike Chesne from Tecton LifeYouTube: https://youtu.be/uTsM_ETF8Us Episode 253: Enduring the Antarctic Chill and Unveiling the Power of Ketones with Akshay Nanavati and Tecton LifeYouTube: https://youtu.be/ockRFjBiOQcConnect with Dr Koutnik:Website: https://andrewkoutnik.com/Instagram: https://www.instagram.com/andrewkoutnikphd/Get In Touch:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/

In this episode of the Flex Diet Podcast, I sit down with my good friend Dr. Tommy Wood to dig into his upcoming book, The Stimulated Mind — a ridiculously practical guide to building a better brain.We get into all kinds of fun rabbit holes: how technology is changing fitness, why lactate (yes, the same stuff you curse during hard intervals) is actually rocket fuel for your brain, and why a solid dose of cardio is one of the most underrated cognitive enhancers out there.We also tackle resistance training, neuroplasticity as you age, and which sports and drills actually move the needle for cognition. And because it’s Tommy, we even wander into the spicy territory of psychedelics and whether they may have a place in brain health.If you want real, actionable strategies to boost memory, focus, and long-term cognitive performance—without drowning in jargon—this episode is for you.Tune in and geek out with us.Sponsors:LMNT electrolyte drink mix: https://drinklmnt.com/Flex 4: Dr Tommy Wood's top 4 ways to improve your brain Preorder The Stimulated Mind: https://www.amazon.com/Stimulated-Mind-Future-Proof-Brain-Dementia/dp/0593797817/ref=sr_1_1Triphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:02:01 Dr. Tommy Wood's Background and Expertise03:15 The Stimulated Mind: Translating Neuroscience into Practical Tips04:01 Sponsors and Special Offers05:09 Interview with Dr. Tommy Wood Begins06:58 The Benefits of High-Intensity Exercise10:37 Lactate and BDNF: Brain Fertilizer17:16 The Potential of Lactate Supplements20:49 The Challenges of Translating Preclinical Science to Humans26:54 The Importance of the Hippocampus and Executive Function29:53 The Benefits of Resistance Training for Cognitive Health32:09 The Cognitive Benefits of Coordinative Training34:30 The Importance of Recreation and Social Interaction37:34 The Humbling Nature of Brazilian Jiu-Jitsu38:12 The Stimulated Mind: Brain Function and Exercise40:06 Neuroplasticity and Aging40:50 Embracing Discomfort for Brain Growth42:47 The Role of Dopamine in Learning45:14 Flow vs. Clutch States in Performance48:41 The Goat Drill: A Complex Motor Skill Exercise53:13 Expanding Cognitive Headroom58:00 Psychedelics and Brain Health01:03:26 Wrapping Up: Book Promotion and Final ThoughtsFlex Diet Podcast Episodes You May Enjoy: Episode 307: The Lost Episode on Body Composition Research with Dr. Tommy Wood and Dr. Ben HouseYouTube: https://youtu.be/ytbNiJ25kiQ Episode 178: Rebroadcast – Insulin and Glucose Myths & more with Dr Tommy WoodYouTube: https://youtu.be/N7LchLtBJr4Connect with Dr. Tommy Wood: Substack: https://substack.com/@betterbrainfitnessInstagram: https://www.instagram.com/drtommywoodWebsite: https://www.drtommywood.com/Get In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/

In this episode of the Flex Diet Podcast, I sit down with Dr. Jeff Rouse from Shiftwave to talk about his mind-bending device that claims to reset your nervous system.I’ll be honest, when I first saw it, I was skeptical. But after trying it at the Parker University conference, I was blown away by what it did. We dig into how the tech works, why it’s so effective for both physical and mental health, and how it’s being used everywhere from mental health therapy to pro sports.Dr. Rouse brings a fascinating mix of psychiatry, quantum biology, and wellness tech expertise to the conversation. He explains the science behind Shift Wave, the principles that make it tick, and some of its wildest protocols, like “synthetic sleep.”If you’re into cutting-edge tools that help you recover faster, feel better, and perform at your best, this one’s worth the listen.Sponsors:Shiftwave: https://shiftwave.co/drmiketnelsonSave $300 with the link above. Note: This is an affiliate link.Daily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Available now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:02:47 Meet Dr. Jeff Rouse: Background and Expertise03:09 Sponsorship and Personal Endorsement05:01 Understanding Shift Wave: Dr. Jeff's Explanation06:37 The Impact of Shift Wave on the Nervous System17:34 Shift Wave in Practice: Real-World Applications31:45 The Role of Sleep in Nervous System Regulation38:03 Synthetic Sleep Protocols: An Innovative Approach39:27 Exploring Synthetic Sleep Protocols40:09 Physiological Effects of Deep Relaxation45:43 Potential Benefits for Athletic Performance49:59 Vagal Nerve Stimulation and Cognitive Enhancement54:42 Mechanoreception and Natural Pathways01:00:14 Personalized Biofeedback and Protocols01:06:37 Daily Use Recommendations for Shift Wave01:11:34 Conclusion and Final ThoughtsFlex Diet Podcasts You May Enjoy: Episode 283: Unlocking Better Sleep and Stress Reduction with Dr. Dan Cohen of Soltec HealthYouTube: https://youtu.be/VInoz9ItGfwEpisode 273: Unlocking Better Sleep: Insights and Strategies from Dr. Chris PerryYouTube: https://youtu.be/BHGBAKtsdWIConnect with Dr Rouse:Website: https://shiftwave.co/Instagram: https://www.instagram.com/shiftwaveproGet In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us

In this episode of the Flex Diet Podcast, I sit down with my good friend Dr. John Rusin to dig into his new book, Pain-Free Performance: Move Better, Train Smarter, and Build an Unbreakable Body. We talk all things movement, strength, and longevity—how to actually perform at a high level without wrecking yourself in the process.John drops some serious wisdom from decades of training and coaching, and we get into the real science behind balancing load, recovery, and pain management so you can keep crushing it for the long haul.If you want to know how to train hard, move well, and build a body that lasts, you’ll definitely want to tune in.Sponsors:Beyond Power Voltra1: https://www.beyond-power.com/michael13Daily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Available now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:03:15 Conversation with Dr. John Russin Begins04:16 The Journey of Writing 'Pain-Free Performance'06:16 Challenges and Insights in Book Writing12:12 Health and Longevity in Fitness Coaching14:54 The Importance of Recovery and Self-Care24:14 The Future of Fitness: Health First Approach27:42 Social Media vs. Real Education in Fitness30:25 The Challenge of Authenticity in Fitness Coaching31:07 The Value of Books and Live Events32:03 Targeting the Right Audience in Fitness44:59 The Importance of Foundational Movement Patterns47:38 Effective Ratios for Balanced Training51:12 Integrating Functional Movements for Injury Prevention56:02 The Role of Storytelling in Fitness Education58:28 Conclusion and Final ThoughtsFlex Diet Podcasts You May Enjoy: Episode 343: Fueling the Corporate Athlete: Stress, Supplements & Performance with Dan Hunterhttps://youtu.be/0ek4XSs62RQ Episode 314: Unlocking Performance & Recovery: IV Therapies & Hyperbaric Oxygen Therapy with Jordyn Paynehttps://youtu.be/qnJHcepDx1cConnect with Dr Rusin:Pain-Free Performance: Move Better, Train Smarter, and Build an Unbreakable Body: https://www.amazon.com/Pain-Free-Performance-Better-Smarter-Unbreakable/dp/162860509XInstagram: https://www.instagram.com/drjohnrusincoaching/Website: https://drjohnrusin.com/Get In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us

In this episode of the Flex Diet Podcast, I sit down with my good friend Dr. Dan Pardi for a deep dive into all things health, longevity, and cognitive performance. We get into the science of stem cells and aging, the real benefits (and limits) of popular supplements, and how nootropics like Ritalin and Modafinil actually work—or don’t—in the real world.We also talk about how to integrate training and movement into insanely busy lives, the psychology of health behavior, and why being flexible in your approach (not just in your hamstrings) is key to long-term success.This episode is brought to you by Quaia Life, where Dan’s doing some fascinating work on cutting-edge supplements designed to optimize health and performance. They’re offering listeners 15% off their products, which you can grab through the link in the show notes.If you want a mix of actionable tips, science-backed insights, and a peek behind the curtain of how top researchers think about performance and aging, you’ll definitely want to tune in.Sponsors:Daily Fitness Insider Newsletter: https://flex-diet.kit.com/bfa1510fa8Qualia: https://qualialife.com/drmike15Coupon Code: DRMIKE15 (listeners get an additional 15% off any Qualia order)Available now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:01:51 Science Communication and Cognitive Performance02:43 Sponsorship and Product Endorsement04:54 The Importance of Flexibility in Training06:39 Integrative and Opportunistic Training15:50 The Psychology of Health and Performance24:12 Quality of Life and Nootropics31:12 Understanding Cognitive Enhancement44:30 Modafinil and Its Effects50:50 Exploring the Benefits and Downsides of a New Drug51:22 Mechanisms and Effects of the Drug52:42 Hallmarks of Aging and Their Impact58:07 Understanding Stem Cells and Their Functions01:01:52 Formulating a Stem Cell Supplement01:10:18 Sequencing Protocols for Optimal Health01:15:13 Challenges and Research in the Supplement Industry01:23:33 Final Thoughts and Recommendations01:34:29 Podcast Conclusion and Disclaimers Flex Diet Podcasts You May Enjoy: Episode 263: Lifestyle, Longevity, and the Future of GLP-1 Agonist Use in Wellness with Christa RymalYouTube: https://youtu.be/SlALIb74KvMEpisode 165: Health, Sports Performance and Longevity Medicine: Dr Rick Cohen with Dr. Mike T NelsonYouTube: https://youtu.be/bYk_wzBJzJYConnect with Dr Pardi:Qualia: https://www.qualialife.com/Instagram: https://www.instagram.com/dan_pardiGet In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us

In this episode of the Flex Diet Podcast, I’m joined by Dr. Eila Wolf, who specializes in functional neurology and Chinese medicine. We dig into how these fields come together to help people dealing with concussions, migraines, and chronic pain — and why traditional approaches often fall short.Dr. Wolf walks us through the science behind her methods, including how acupuncture, vestibular work, and eye movement assessments can reveal what’s really going on in the brain after an injury. We also talk about her new book, The Concussion Breakthrough, and how it’s helping patients who’ve been struggling with long-term symptoms finally find a path forward.If you want a deeper understanding of how the brain heals — and how functional neurology can help you or someone you know recover faster and more completely — you’ll get a ton out of this conversation.Sponsors:Beyond Power Voltra 1: https://www.beyond-power.com/michael13Tecton Ketone Esters: https://tectonketones.comAvailable now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:00:46 Exploring Functional Neurology01:23 Concussions and Eye Movements02:09 Dr. Wolf’s Book and Newsletter02:42 Starting the Conversation02:49 Dr. Wolf’s Lecture at Northwestern03:40 Better PowerPoint Presentation Tips04:29 Challenges of Creating New Talks05:57 AI in Research and Presentation07:22 Cadaver Lab Experience in Toronto09:07 Acupuncture and Anatomical Research09:54 History and Acceptance of Chinese Medicine11:47 Skepticism and Evidence in Acupuncture13:41 Research Design Challenges17:18 Innovative Acupuncture Studies21:34 Psychedelics and Research23:15 Dr. Wolf’s Journey into Acupuncture27:08 Favorite Herbs and Their Benefits29:16 Introduction to Functional Neurology33:18 Case Studies and Clinical Insights35:59 Sensory Tricks for Migraines38:13 Mechanisms Behind Sensory Tricks39:32 Light Sensitivity and the Midbrain40:45 Personal Experience with a Health App41:31 Understanding Light Sensitivity42:59 Case Study: Pupil Response and Eye Pain44:09 Eye Movements & Concussion Diagnosis47:06 Gaze Stability and Neurological Insights52:19 The Concussion Breakthrough Book55:45 Complex Cases in Functional Neurology01:04:27 Visual + Vestibular Integration01:14:55 Final Thoughts and Resources Flex Diet Podcasts You May Enjoy: Episode 132: The Effects of Creatine Supplements on Brain Function, Concussion, and Sports Performance with Dr Eric RawsonYouTube: https://youtu.be/g7f8yHNlawU Episode 311: Maximizing Athletic Performance with Neurology: Insights from Dr. Dylan SeeleyYouTube: https://www.youtube.com/watch?v=bnuYQ-GJ6toConnect with Dr Wolf:The Concussion Breakthrough: https://www.amazon.com/Concussion-Breakthrough-Discover-Missing-Recovery/dp/B0FDBLVDVHWebsite: https://www.acupunctureneurology.com/Instagram: https://www.instagram.com/ayla_wolf354Get In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us

In this episode of the Flex Diet Podcast, I’m joined by Erin Silver Lee, the CEO of Flow Neuroscience. We dig into some seriously cool stuff — including Flow’s recent acquisition of the Halo device, which uses non-invasive brain stimulation (TDCS) to boost both athletic and mental performance.Erin and I talk about how this tech works, what the current research says, and how it’s being applied to improve focus, sleep, neuroplasticity, and overall brain health. We also get into the real-world side of things — from navigating FDA regulations to running clinical trials and shaping the future of personalized brain optimization.If you’re curious about where neuroscience meets performance — and how safe, evidence-based brain stimulation might fit into the next generation of recovery and training tools — you’ll want to check this one out.Sponsors:Beyond Power Voltra 1: https://www.beyond-power.com/michael13Tecton Ketone Esters: https://tectonketones.comAvailable now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:00:38 Background on Halo Device and Flow Neuroscience01:50 Acquisition and Technology Insights02:09 FDA Regulation and Consumer Approval06:02 New Device Focus and User Benefits07:29 Device Design and Usage08:45 Impact on Sleep and Mental Performance16:17 Personalization and Future Developments26:06 Focus and Concentration Benefits29:33 Navigating FDA Regulations30:35 Depression Treatment Success in Europe30:51 Challenges with Regulatory Approval31:50 Real-World Success and Halo Product Launch33:23 Navigating FDA Approval and Bias42:45 Clinical Trials and Expanding Indications51:25 Brain Health and Personal Practices55:33 Podcast Conclusion and Listener Information Flex Diet Podcasts You May Enjoy: Episode 346: From Navy SEAL to Neuroscience: Dr. Blaine Lints on Ibogaine and PerformanceYouTube: https://youtu.be/8UNGgyqBWm0 Episode 241: A New Perspective on Brain Health with Dr. Shaun KornfeldYouTube: https://youtu.be/1HcgPp6Wz7QConnect with Flow Neuroscience:Website: https://www.haloneuroscience.com/Facebook: https://www.facebook.com/halo.neuroscienceYouTube: https://www.youtube.com/@HaloNeuroscienceLinkedIn: https://www.linkedin.com/company/halo-neuroscience/Instagram: https://www.instagram.com/halo.neuro/Get In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us

In this episode of the Flex Diet Podcast, I dive into practical ways to boost muscle growth, enhance performance, and improve body composition — all within a flexible, health-focused framework.I also talk about my Physiologic Flexibility Certification, which is closing for enrollment soon, and unpack key concepts like Human Dynamic Range (HDR) and cross-adaptation. HDR is all about building a wider physiological range — the ability to handle more stress and recover faster — while cross-adaptation looks at how training one system (like heat or hypoxia) can improve others.Plus, I dig into new research and share actionable strategies you can use right now to strengthen your cardiovascular and respiratory systems.Sponsors:Physiologic Flexibility Certification Course open Monday, Oct. 13 to Monday, Oct. 20: https://miketnelsons.samcart.com/products/physflex/Instagram: https://www.instagram.com/drmiketnelson/Triphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:00:20 Important Announcement: Physiologic Flexibility Certification01:57 Key Concepts in Physiologic Flexibility02:14 Human Dynamic Range Explained06:01 Cross Adaptation: Heat and Hypoxia08:24 Research Studies and Findings20:33 Practical Applications and Protocols24:32 Conclusion and Certification Details28:21 Disclaimer and Final NotesGet In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/

In this episode, I’m sharing a special rebroadcast of my chat with Dr. Mikki Williden all about physiologic flexibility, including how to train your body to handle stress and adapt better. We cover metabolic flexibility, heat and cold exposure, sauna and cold therapy, lactate and buffering systems, plus CO₂ and O₂ tolerance. You’ll learn how these systems connect to boost performance, recovery, and body composition in a healthy, sustainable way.Sponsor:Physiologic Flexibility Certification Course open Monday, Oct. 13 to Monday, Oct. 20: https://miketnelsons.samcart.com/products/physflex/Triphasic 2 book now available!Go to https://triphasic2.com/Episode Chapters:01:39 Introduction by Dr. Mikki Williden02:43 Dr. Mike T. Nelson's Background06:53 Discussion on Metabolic and Physiologic Flexibility15:09 Personal Experiences and Experiments16:28 Cold Exposure and Its Effects25:28 Heat Exposure and Adaptation31:36 Psychological Benefits of Cold Exposure34:31 Practical Recommendations for Cold and Heat Exposure39:52 Understanding pH Balance and Acid Tolerance41:52 Understanding Lactate and Its Role in Exercise43:19 Buffering Systems and Supplements49:11 High-Intensity Interval Training (HIIT) Insights53:02 Breathing Techniques and CO2 Tolerance57:44 Altitude Training and Oxygen Regulation01:06:34 Metabolic Flexibility and Ketones01:14:39 Conclusion and Final ThoughtsGet In Touch with Dr Mike:Instagram: https://www.instagram.com/drmiketnelson/YouTube: https://www.youtube.com/channel/UCn1aTbQqHglfNrENPm0GTpgEmail: https://miketnelson.com/contact-us/