Does Israel's Qatar strike end hopes for diplomatic end to war?

US President Trump has landed in London for his second state visit to the UK. His arrival coincides with some good news for Keir Starmer as Microsoft announces a £22 billion investment in the UK. We speak to Jeremy Hunt, foreign secretary during Donald Trump’s last state visit, about preparing for the president’s public appearances. Also on the programme: as new data shows continued weakness in the labour market, we'll hear from young people trying to find work; and Robert Redford has died at 89, we hear from the biographer who became his friend.

The Conservative MP Danny Kruger has become the first sitting Conservative MP to defect to Reform UK. Lord Soames, Winston Churchill's grandson, tells us that his former colleague's claim that the Conservatives are "over" is "absolute nonsense".On the eve of President Trump's second state visit, we examine how free speech has become an area of tension between the UK and US governments.And we look at the other big winner at last night's Emmys - medical drama The Pitt, which has been lauded by both critics and doctors alike.

A suspect in the murder of US conservative activist Charlie Kirk has been arrested. Tyler Robinson is 22. He was confronted by his father, who recognised pictures of him released by the FBI and, with the help of a pastor, persuaded him to hand himself in.Sir Keir Starmer is facing growing criticism from within the Labour Party after he sacked Lord Mandelson as UK ambassador to the US, with one backbencher saying he "doesn't seem up to the job".And are we too reliant on potentially vulnerable global satellite positioning systems? An industry leader says near misses are more common than you may think.

Lord Mandelson has been sacked as Ambassador to Washington over his ties to the sex offender Jeffery Epstein, just days before President Trump's state visit to the UK. We ask what questions this raises about the Prime Minister's own judgement.Also on the programme:The killer of Charlie Kirk - the American right-wing political activist and ally of President Trump - is still at large. We speak to a British student who debated him at Oxford earlier this year.And as the sequel to This is Spinal Tap is released - we ask whether it'll strike a chord, 40 years on from the iconic original.

Charlie Kirk, the US conservative activist and major ally of President Donald Trump, has been shot dead while speaking at a university campus event in Utah. Police are still looking for the attacker. On social media, Trump wrote, "The Great, and even Legendary, Charlie Kirk, is dead. No one understood or had the Heart of the Youth in the United States of America better than Charlie".Pressure continues to mount on the government over the future of Lord Mandelson as UK ambassador to the US, as more revelations emerge about his past association with Jeffrey Epstein. We speak to one Labour MP who says Mandelson should be sacked.And a defence of the much-maligned author of the Da Vinci Code - Dan Brown - as his first novel in eight years is released.

There's been a dramatic escalation today in Israel's war against Hamas, as a strike on the Hamas leadership in Qatar drew widespread condemnation. Has it killed off any hope of a diplomatic solution to the war in Gaza?Also:France's President Macron has announced his new pick for Prime Minister - 24 hours after losing his last one. We're live in Paris.And we hear about the impact of a recording studio for young people in Nottingham - where Prince Harry announced a £1 million donation to Children in Need.

A no-confidence vote in France has led to the ousting of the country’s Prime Minister Francois Bayrou just nine months after he took office. It now means President Emmanuel Macron has lost his third prime minister in just over a year. We explore how opposition parties are reacting to the news and how the crisis might be resolved.Also: A BBC exclusive interview with the comedian Graham Linehan, after he was arrested at Heathrow airport for his social media posts. And the remarkable story of one man who survived six days with a broken leg on the edge of a Norwegian glacier.

As Sir Keir Starmer delivers a sweeping cabinet reshuffle at the end of perhaps the most bruising week of his premiership so far, we ask his authorised biographer whether he can still turn it around. Also:The Reform UK leader, Nigel Farage, has told his party's conference to be ready for a general election in 2027. And the Duchess of Kent, the oldest member of the royal family, has died at 92.

The political future of Deputy Prime Minister Angela Rayner hangs in the balance as Westminster awaits a report into her tax affairs by Keir Starmer’s independent adviser on ministerial standards. Rayner has admitted under-paying stamp duty on a second home in Hove, but says she was acting on incorrect legal advice. Also on the programme: an icon of fashion, Italian designer Georgio Armani, has died at the age of 91; and we visit the modern-day almshouse shortlisted for the Stirling Prize for architecture.

Members of the opposition have called for Deputy Prime Minister Angela Rayner to resign after she admitted she didn't pay enough stamp duty on a flat she purchased in Hove. She denied she had tried to dodge the extra tax, blaming the "mistake" on initial legal advice that failed to "properly take account" of the situation. Sir Keir Starmer stood by his deputy at Prime Minister's Questions, saying he was "very proud to sit alongside" her. We look at public perceptions of her and hear from Sir Keir Starmer's former political director.The Portuguese government has declared a day of national mourning tomorrow - after an accident on Lisbon's famous funicular railway this evening left at least fifteen people - including foreigners - dead.And Melvyn Bragg has stepped down as host of BBC Radio 4's In Our Time after 26 years. We hear from frequent guest Angie Hobbs and superfan Sir Simon Schama.