Dr. Mark Latina and Dr. Gus Gazzard: SLT, LiGHT Trial, Glaucoma

Dr. Samuel Masket shares his journey into medicine, from initially planning to become a veterinarian to discovering his passion for ophthalmology. He recounts the serendipitous events that led him to pursue a career in ophthalmology and the pivotal moments that shaped his path. Dr. Masket discusses his interest in ophthalmic diagnostics and the excitement of being at the forefront of cataract technology. He highlights the collaboration between surgeons and industry in advancing the field of cataract surgery. Despite initial resistance, Dr. Masket and his colleagues played a significant role in popularizing phoacoemulsification and revolutionizing cataract surgery. Dr. Masket discusses his early years in California, his work with IOLs, research on dysphotopsia, efforts to prevent endophthalmitis, and the establishment of the Mask It Foundation. Takeaways Serendipitous events can shape one's career path and lead to unexpected opportunities. Passion for a specific field can be sparked by personal experiences and exposure to innovative techniques. Collaboration between surgeons and industry can drive advancements in medical technology. Persistence and dedication to publishing research can contribute to the growth and development of a field. Dr. Masket's early years in California were marked by a progressive and supportive environment for ophthalmic advancements. His work with IOLs included the development of a goal wing haptic design and the study of dysphotopsia. Dr. Masket conducted research on endophthalmitis prevention, highlighting the importance of intracameral antibiotics. The Masket Foundation, established by Dr. Masket and his partner Dr. Nicole Fram, provides assistance to uninsured and underinsured patients in need of anterior segment surgery. Chapters 00:00 The Journey into Medicine 04:00 Discovering Ophthalmology 07:49 Research and Innovation in Eye Care 12:05 Military Service and Clinical Experience 15:56 Transitioning to California 21:46 The Rise of Cataract Surgery 29:57 Overcoming Resistance to Phaco Surgery 34:18 The Progressive Landscape of California Medicine 37:41 Innovations in Intraocular Lenses (IOLs) 50:19 Understanding Dysphotopsia in Eye Surgery 59:03 The Masket Foundation and Community Impact

Dr. Marguerite McDonald shares her journey in medicine and ophthalmology, from her childhood experiences with poor vision to her groundbreaking work in refractive surgery. She recounts her introduction to ophthalmology through a retinoblastoma clinic and her research on isoenzyme patterns in retinoblastoma. Dr. McDonald discusses her residency and fellowship experiences, including her involvement in the PERK study on radial keratotomy. She then delves into the development of the excimer laser and the challenges and controversies she faced during the early stages of laser vision correction. Finally, she reflects on the current state of LASIK and the advancements in refractive surgery. In this conversation, Dr. Marguerite McDonald discusses her experiences and contributions in the field of ophthalmology. She talks about the challenges with LASIK and the importance of highlighting successful outcomes. Dr. McDonald also shares her journey as the first female president of ASCRS and ISRS, and her involvement with Ophthalmic Women Leaders (OWL). She reflects on her most meaningful contributions to the field, including her work on retinoblastoma and laser vision correction. Finally, Dr. McDonald discusses exciting developments in the field, such as the EVO ICL and temporary procedures for presbyopia. Takeaways Dr. Marguerite McDonald's journey in medicine and ophthalmology was shaped by her personal experiences with poor vision and her desire to help others see. Her research on isoenzyme patterns in retinoblastoma and her work on the PERK study on radial keratotomy were significant contributions to the field of ophthalmology. Dr. McDonald played a pivotal role in the development of laser vision correction, including the use of the excimer laser and the transition to LASIK. Despite facing controversy and skepticism, Dr. McDonald's dedication to data-driven research and patient care has helped shape the field of refractive surgery. Highlighting successful outcomes is important to counteract negative publicity and encourage more suitable candidates to proceed with LASIK. Dr. Marguerite McDonald's journey as the first female president of ASCRS and ISRS highlights the progress made in promoting diversity and gender equality in the field of ophthalmology. Ophthalmic Women Leaders (OWL) provides a platform for networking and professional development for women in the ophthalmology industry. Dr. McDonald's contributions to the field include her work on retinoblastoma, laser vision correction, and the development of the EVO ICL. Chapters with Timestamps 00:00 - Introduction and Early Life 00:40 - The Near-Drowning Incident and Discovery of Myopia 03:00 - First Glasses and Introduction to Optometry 05:23 - Medical School Challenges and Rotation in Retinoblastoma 07:45 - Research on Retinoblastoma Isoenzymes 10:06 - Internship at Lenox Hill and Residency at Manhattan Eye 12:23 - Residency Interview Experiences and Film Festival Award 14:45 - LSU Fellowship and Refractive Surgery Involvement 17:08 - Work on Epicardifakia and Radial Keratotomy Research 19:34 - Transition to Excimer Laser Development 21:59 - Early Laser Research Challenges 24:29 - Animal Testing, First Human Case, and FDA Interactions 26:52 - The Alberta Cassidy Case and Human Trials 29:18 - LSU Trailer Experiments and Data Findings 31:40 - Controversy Over Blind Eye Study 34:01 - Advances in Laser Technology and Flying Spot Lasers 36:26 - First Sighted Patients and Scrutiny 38:48 - Evolution of LASIK and Femtosecond Lasers 41:11 - Barriers to LASIK Adoption 43:36 - Leadership Roles and Breaking Barriers 46:02 - Founding of OWL and Professional Networking 48:21 - Reflections on Career Achievements 50:49 - Exciting Future Developments in Ophthalmology 51:52 - Closing Remarks and Sponsor Acknowledgments

Dr. Richard Lindstrom shares his journey in ophthalmology, from initially intending to join his family's construction business to becoming a renowned ophthalmologist and innovator. He discusses how medicine chose him and his path to specializing in ophthalmology. Dr. Lindstrom shares his experience in private practice and academia, as well as his involvement in research, teaching, and industry collaboration. He also highlights the importance of being open to innovation and the challenges faced by pioneers in the field. Additionally, he discusses his patents and his role as president of various ophthalmology organizations. Dr. Richard L. Lindstrom discusses the path to becoming a Key Opinion Leader (KOL) in the field of ophthalmology. He emphasizes the importance of being involved in clinical trials, conducting research, and teaching colleagues. Dr. Lindstrom also shares his experience as the Chief Medical Editor of Ocular Surgery News and highlights the importance of education and innovation in the field. He discusses his most impactful publications and the advancements in various areas of ophthalmology, including cataract surgery, glaucoma treatment, corneal refractive surgery, and retinal diseases. Dr. Lindstrom encourages young ophthalmologists to embrace innovation and continue learning throughout their careers. Chapters 00:00 Dr. Richard Lindstrom's Journey in Ophthalmology 05:19 Balancing Private Practice, Academia, and Research 16:20 The Importance of Being Open to Innovation 28:53 Innovations in Ophthalmology: Accommodating IOLs 33:00 The Changing Landscape of Ophthalmology Education 35:00 Becoming a Key Opinion Leader 42:07 The Role of Education and Innovation 42:37 Dr. Lindstrom's Work with Ocular Surgery News 48:39 The Development of Diffractive Multifocal IOLs 53:16 The Most Influential Advances in Ophthalmology 59:00 The Shift in Glaucoma Treatment 01:03:22 Advice for Young Ophthalmologists Keywords ophthalmology, journey, medicine, private practice, academia, research, teaching, industry collaboration, innovation, patents, president, ophthalmology organizations, ophthalmology, Key Opinion Leader, clinical trials, research, education, innovation, cataract surgery, glaucoma treatment, corneal refractive surgery, retinal diseases

Dr. Steve Charles discusses his early influences and career path, including his decision to become an ophthalmologist. He shares his focus on vitreoretinal surgery and the importance of collaboration and education in his field. Dr. Charles also talks about his experience with product development at Alcon and the challenges of finance in startups. He emphasizes the impact of his innovations in vitrectomy and advancements in surgical equipment. Dr. Charles discusses the importance of publications and education, as well as the global impact of his work. He also shares his thoughts on the most important technological advancement in his field. In this conversation, Dr. Steve Charles discusses his experience flying jets and the importance of flying like a professional. He shares his journey of becoming a pilot and the types of jets he has flown. Dr. Charles also talks about the concept of aspirational innovation and provides advice for starting a company. He emphasizes the importance of constant learning and building the right team. Takeaways Early influences and exposure to art, engineering, and medicine shaped Dr. Charles' career path. Collaboration and education are crucial in the field of vitreoretinal surgery. Product development requires a strong partnership with a company and a focus on solving problems. Finance is a challenge in the medtech industry, and the return on investment has not been favorable. Dr. Charles' innovations in vitrectomy and advancements in surgical equipment have had a significant impact. Publications and education play a vital role in sharing knowledge and improving patient care. Dr. Charles emphasizes the importance of global impact and sustainability in healthcare. Technique and technology are key factors in the success of vitreoretinal surgery. Anti-VEGF therapy has been a game-changer in the treatment of retinal diseases. The most important technological advancement in Dr. Charles' field is high-speed disposable cutters. Flying jets requires skill and professionalism. To become a pilot, it is important to learn from experienced instructors and fly like a professional. Constantly learning about technology is crucial for success in innovation. When starting a company, having a clear product and building the right team are essential. Chapters 00:00 Early Influences and Career Path 03:08 Becoming an Ophthalmologist 08:24 Focus on Vitreoretinal Surgery 10:11 Product Development with Alcon 12:06 Importance of Collaboration and Education 19:07 Challenges in Medtech Finance 22:11 The Impact of Product Development 24:20 The Importance of Learning and Teaching 27:43 Early Innovations in Vitrectomy 29:05 Advancements in Surgical Equipment 34:06 The Role of Publications and Education 37:15 The Global Impact of Product Development 39:04 Writing the Book and Importance of Technique and Technology 42:37 The Evolution of Surgical Equipment 46:10 Advancements in Vitrectomy Techniques 48:07 The Impact of Anti-VEGF Therapy 49:31 Flying Jets 50:13 Becoming a Pilot 51:08 Flying Like a Pro 52:37 Aspirational Innovation 53:34 Advice for Starting a Company 54:03 Constant Learning 54:33 Building the Right Team 55:18 Closing Remarks

Dr. Kenneth J. Hoffer shares his journey into ophthalmology, starting from his humble beginnings as a high school student with a dream. He overcame financial obstacles and received scholarships to pursue his medical education. Initially interested in heart surgery, he was inspired to become an ophthalmologist after observing a cataract operation. Dr. Hoffer became a pioneer in intraocular lens (IOL) implantation and power calculation, founding the American Intra-Ocular Implant Society (AIOIS), now known as ASCRS, and the Journal of Cataract and Refractive Surgery (JCRS). He also played a role in the formation of the European Society of Cataract and Refractive Surgery (ESCRS). Dr. Hoffer reflects on his experiences as the editor of JCRS and his contributions to the field. He discusses the challenges of editing the journal and the meticulous process of typesetting and printing. Dr. Hoffer also shares his pride in the journal and its impact on lens implant surgery, calculations, and techniques. He also discusses his invention of the Hoffer Split Bifocal, the first multifocal intraocular lens, and his mentors who influenced his career. Takeaways Dr. Kenneth J. Hoffer's journey into ophthalmology started with a dream and overcoming financial obstacles. He was inspired to become an ophthalmologist after observing a cataract operation. Dr. Hoffer became a pioneer in intraocular lens (IOL) implantation and power calculation, performing the first A-scan ultrasound IOL power calculation in the United States. He founded the American Intra-Ocular Implant Society (AIOIS) and the Journal of Cataract and Refractive Surgery. Dr. Hoffer played a role in the formation of the European Society of Cataract and Refractive Surgery (ESCRS). Editing a journal requires attention to detail and a strong command of language. The Journal of Cataract and Refractive Surgery (JCRS) has played a significant role in advancing lens implant calculations and surgical techniques. Dr. Kenneth Hoffer invented the Hoffer Split Bifocal, the first multifocal intraocular lens. Mentors, such as Drs. Karl Ossoinig, John Gilmore, Norman Jaffe, and Robert Drews, played a crucial role in Dr. Hoffer's career. Keywords ophthalmology, journey, scholarships, medical education, heart surgery, cataract operation, intraocular lens, IOL, power calculation, American Intra-Ocular Implant Society, AIOIS, Journal of Cataract and Refractive Surgery, European Society of Cataract and Refractive Surgery, ESCRS, journal editing, typesetting, printing, lens implant calculations, surgical techniques, multifocal intraocular lens, mentors

In this insightful episode, Dr. Micheletti engages with two renowned ophthalmologists, Dr. Mark Latina and Dr. Gus Gazzard, discussing the evolution and impact of laser technology in the treatment of glaucoma. Dr. Latina, known for developing Selective Laser Trabeculoplasty (SLT), recounts his journey from chemistry to ophthalmology, emphasizing the role of technology and innovation in his career. He shares his experiences with the excimer laser, dynamic laser spectroscopy, and the development of SLT, highlighting the importance of laser technology in treating glaucoma efficiently and safely. Dr. Gazzard, on the other hand, discusses his medical journey and his involvement in pivotal clinical trials, such as the Light Trial, which demonstrated the effectiveness of SLT as a primary treatment for glaucoma. He elaborates on the long-term benefits of SLT, including its potential to rejuvenate the trabecular meshwork and maintain intraocular pressure more consistently compared to traditional medication. The conversation also explores the future of glaucoma treatment, touching upon exciting developments like direct SLT, gene therapy, and stem cell research. Dr. Gazzard's interest in the genetics of response to laser treatment and Dr. Latina's perspective on genetic therapies suggest a promising direction for personalized medicine in ophthalmology. In closing, both guests reflect on the most significant innovations in their careers. Dr. Gazzard highlights the importance of the capsulorhexis technique in cataract surgery, while Dr. Latina reaffirms the impact of SLT.

In this episode of "The History of Eyecare," Dr. Morgan Micheletti talks with Dr. Uday Devgan, an accomplished ophthalmologist and expert in cataract surgery. Dr. Devgan recounts his journey into medicine, starting with his initial interests and leading to his specialization in cataract and refractive surgery. He discusses the role of mentors in his career and his experiences at the University of Southern California and UCLA. The conversation then shifts to Dr. Devgan's contributions to ophthalmology education, particularly through his platform, CataractCoach.com. He emphasizes the importance of ongoing learning and sharing knowledge within the medical community. Dr. Devgan also shares experiences from his international work and involvement in early clinical trials, reflecting his patient-centered approach to ophthalmology. Dr. Devgan offers advice for young surgeons and expresses his enthusiasm for future innovations in the field, especially in the development of accommodating intraocular lenses. His insights provide a comprehensive view of the advancements in eyecare and the potential for future technologies to enhance patient care.

In this episode of "The History of Eyecare," Dr. Morgan Micheletti sits down with Mr. Nick Curtis, a well-respected figure in the world of eyecare. The discussion begins with a look into Mr. Curtis's early life, where his passion for sports led to a scholarship at Northwestern and a pivotal career start at IBM. This foundation set the stage for his remarkable journey into the field of eye care. As the conversation unfolds, Mr. Curtis shares his experiences during his time at American Hospital Supply's V Mueller division, marking his foray into ophthalmology. His significant role at Chiron Vision is a highlight, where he was instrumental in developing new surgical methods and devices. These innovations not only transformed patient care in eye surgery but also marked a significant advancement in the field. Wrapping up the episode, Mr. Curtis offers his insights on his tenure with LENSAR, emphasizing the evolution of ophthalmic technology and the critical importance of customer-focused strategies. His reflections provide an inspiring look at the relentless pursuit of progress in eye care, offering listeners a unique perspective on the industry's ongoing evolution.

In this enlightening episode of 'The History of Eyecare,' host Dr. Morgan Micheletti discovers the inspiring journey of Dr. Denise Visco, an esteemed ophthalmologist known for her dedication to cataract surgery and innovation in eye care. Dr. Visco recounts her unique path into the world of ophthalmology, sharing the pivotal moments and decisions that shaped her career. Her passion for eye care shines through as she discusses the early challenges she faced and the exhilarating experience of starting her own practice. Dr. Micheletti and Dr. Visco engage in a fascinating conversation about the latest advancements in eye care technology and surgical techniques. Dr. Visco shares her insights into the evolution of procedures like LASIK and SMILE, highlighting the transformative impact these techniques have had on patient care. The discussion illuminates the constant progression of eye care, underscoring the importance of embracing new technologies to enhance patient outcomes. Concluding the episode, Dr. Visco reflects on the broader implications of these advancements for the field of ophthalmology. The dialogue emphasizes the significance of continuous learning, mentorship, and the drive to push the boundaries of what's possible in eye care. Listeners will leave with a deeper appreciation of the dynamic and ever-evolving nature of ophthalmology, inspired by Dr. Visco's commitment to excellence and innovation in the field.

In this engaging episode of "The History of Eyecare," host Dr. Morgan Micheletti sits down with the esteemed Dr. James Loden, a trailblazer in cataract, refractive, and anterior segment surgery. They explore Dr. Loden's early inspiration from his father and his path to becoming a leading figure in eye care. The episode highlights Dr. Loden's significant contributions to cataract and LASIK surgery, underscoring his innovative approach. The discussion then shifts to Dr. Loden's experiences during his medical training and his involvement in developing new surgical techniques. His reflections on the evolution of ophthalmology provide a unique insight into the challenges and advancements within the specialty. Dr. Loden also shares his experiences in teaching and mentoring, emphasizing the importance of education in his career. Finally, the episode concludes with Dr. Loden sharing his perspectives on the future of eye care. He stresses the importance of patient-focused care, drawing on personal anecdotes and experiences with his mentors. This episode offers a comprehensive look into Dr. Loden's professional journey and his profound impact on ophthalmology.