Can GLP-1s do for opioid addiction what they did for weight loss?

GLP-1 medications revolutionized the way we treat chronic weight management and diabetes by helping to quiet “food noise”. Researchers are now looking into whether these medications can also be used to dampen “drug noise” and help treat people with substance use disorders.Alanna Smith is a health reporter for The Globe and she’s been looking into what’s going on with the research around GLP-1s being used to tread opioid addiction. She’s on the show to talk about the excitement and the reluctance on this potential treatment.Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In early August, OpenAI hosted dozens of lifestyle creators at an upstate New York resort for a weekend they called Summer Club. There was beekeeping. There were farm-to-table dinners. And in between, there were sessions on how to use ChatGPT. The ensuing backlash was swift, especially against the female influencers.This episode of Machines Like Us delves into the money pouring into AI marketing that goes far beyond a luxury brand trip. Tech billionaires and super PACs are spending millions to quietly flood your social media feeds. Some have paid influencers for undisclosed deals pushing AI-positive and anti-China messaging. Others have gone so far as to fund radical anti-AI meme accounts that threaten their own CEOs – all to make their critics look unhinged.Tech and culture journalist Taylor Lorenz has spent more than a decade reporting on online creators. She’s been following the dark money behind these co-ordinated campaigns to buy up digital influence and shift the public debate around AI. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The European Union has dropped its offer to give Canada the status of ‘associate member.’ This comes after pushback from some member states and reluctance from Canadian politicians to use the term. But both sides insist they are not abandoning their new efforts at forging a closer partnership.Today, EU and Canadian officials are meeting in Montreal to try to hammer out details around strengthening ties in trade, security and finances. Steven Chase is in Montreal to cover this summit and explains how both governments are trying to build an alliance that makes them less dependent on the U.S.Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Americans will vote for members of the U.S. Congress in the midterm elections on Nov. 3. But in a number of states, this year’s election will have a major factor: Canada. A combination of President Donald Trump’s tariffs on a range of industries, to threats of annexation and a loss of revenue from tourism – has made Canada and its relations with the U.S. prime voting issues.Nathan VanderKlippe, international correspondent for The Globe, has been covering the U.S. midterms in the lead-up to voting day. He’ll explain why Canada matters in some key races and how the midterms are being seen by observers as a referendum on Trump 2.0Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Canadians reported over $700-million lost to scams in 2025, up from $645-million the year before; that figure is recognized to be a massive undercount because most scams go unreported. Scams are only getting more sophisticated and convincing. Today, we’re talking about the most common types of scams: investment, authority and romance.Alexandra Posadzki is The Globe’s financial crime and cybercrime reporter. She’ll walk us through the main scams Canadians face, and why they’re so hard to stop. We also speak with a man who lost thousands of dollars to a scam himself.Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The Canadian government has invested billions in critical mineral companies in an effort to boost the sector so it can compete against China. But mining projects always come with a lot of risk for investors. So is this a smart strategy for a government to adopt?Niall McGee is the mining reporter for The Globe. He looked into which projects the federal government is investing in, what they hope will come of their investments and whether this bet is worth taking.Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

On Saturday, B.C. voters head to the polls in a snap provincial election. BC NDP Leader David Eby’s rationale for the election, held two years ahead of schedule, was to get a stronger mandate amidst a trade war. His critics called it a gamble that could threaten Eby’s government. Now, the BC Conservative party is neck in neck with the NDP and a new, young challenger could come out of the election holding the balance of power.Mike Hager, Globe reporter in Vancouver, has been covering the election campaign. He’ll take us through the controversial election call, why the Conservatives have made a comeback in the polls and what the biggest voting issues are on the ballot.Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Four people were killed and dozens injured in a fire at Canadian Forces Base Wainwright in Alberta on Saturday. Prime Minister Mark Carney called it one of the worst tragedies for the Armed Forces on Canadian soil in peacetime.Today, Globe feature writer Jana G. Pruden is on the show. She was in Wainwright this week and she’ll tell us what we know, and what’s still unknown, about the tragedy.Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Albertans firmly rejected the option to separate from Canada in Monday night’s referendum vote, with 75 per cent of voters opting to keep the province in the country. But will that mark the end of the separatist movement in Alberta? And what does it mean for Premier Danielle Smith and her future?Tyler Dawson is a Globe columnist and Opinion editor based in Edmonton. He is also the author of the book The Republic of Alberta: An Idea That Won’t Go Away. He explains the political consequences of the results of the separation question as well as the other nine questions that Albertans voted on.Questions? Comments? Ideas? E-mail us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Household chores can be seen as a drain on your time. But to some AI companies, how you do those chores is valuable data. Apps like Atlas Capture are using videos of people sweeping or cleaning a toilet to train humanoid robots. Who are the people doing this work for AI companies? And is the pay (usually around US$3 per hour) worth their time?Joe Castaldo is The Globe’s AI and tech reporter and he tried out the technology firsthand. He’s on the show to tell us what this work looks like, what the people doing this labour think about it and what it means for humanity when we teach robots to do chores.Questions? Comments? Ideas? Email us at [email protected] Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.