Reanalysis of Popular Antidepressant Trial Uncovers Reporting Flaws

Sodium is an essential electrolyte that supports fluid balance, nerve signaling, muscle contraction, and heartbeat coordination; even small drops in blood sodium disrupt these essential functions A Virginia Tech study found that low blood sodium amplifies the effects of flecainide, a common rhythm-control drug, by disrupting key electrical support systems between heart cells Restoring sodium to the normal range reversed conduction delays. This confirms that the effects were due to a temporary sodium imbalance People on sodium channel blockers need to monitor sodium levels closely, as common triggers like diuretics or illness cause dangerous delays in heart signal conduction Most adults do well with around 3,500 milligrams of sodium daily, especially when it comes from unprocessed, mineral-rich sources balanced by adequate potassium intake

A reanalysis of a study found that fluoxetine alone showed no measurable benefit over placebo in treating adolescent depression after 12 weeks Researchers uncovered 11 additional suicide-related events that were hidden or misclassified, bringing the total to 21 serious incidents Statistical tactics and selective reporting made fluoxetine appear safer and more effective than it really was in clinical trials A different reanalysis mentioned that adverse events and many side effects were minimized or excluded from the original reports Improving gut health, getting regular exercise, undergoing therapy, and optimizing vitamin D are viable approaches for treating depression

Glutamine is the most abundant amino acid in your body, supporting tissue repair, immune function, and energy production, while also helping protect your eyes from vision loss Research shows your eyes rely on glutamine to fuel photoreceptors, the light-sensing cells in the retina, making it a key nutrient for long-term visual health When glutamine metabolism is disrupted, photoreceptors degenerate rapidly, triggering harmful stress pathways that accelerate retinal thinning and increase the risk of blindness Studies demonstrate that restoring glutamine balance calms cellular stress, preserves retinal thickness, and keeps eye cells alive, offering new strategies for preventing eye disease You can support natural glutamine levels through diet by eating foods such as grass fed beef, wild-caught Alaskan salmon, pastured eggs, raw dairy, spinach, cabbage, beans, and even white rice

For several decades, saturated fat was wrongly blamed for heart disease, while vegetable oils quietly caused a surge in obesity, inflammation, and chronic metabolic disorders Newly appointed FDA commissioner Dr. Marty Makary is now leading efforts to revise outdated dietary guidelines that were built on cherry-picked data from Ancel Keys’ Seven Countries Study A 2016 BMJ-published reanalysis found replacing saturated fat with linoleic acid-rich vegetable oils increased cardiovascular deaths, despite lowering cholesterol Investigative journalist Dr. Maryanne Demasi faced vicious backlash after exposing the flawed science behind saturated fat demonization in her documentary “Heart of the Matter” Industrial seed oils like canola and soybean are now linked to mitochondrial damage, inflammation, and chronic illness — while saturated fat is finally being recognized as metabolically supportive

Targeted probiotic strains improve endurance, strength, recovery, and mental resilience by supporting gut integrity, reducing inflammation, and enhancing nutrient absorption Intense training damages your gut lining and weakens immunity, but probiotics help maintain barrier function and prevent bacterial toxins from triggering systemic inflammation Specific strains deliver specific benefits, such as Lactobacillus plantarum for endurance, Bacillus coagulans for muscle recovery, and Lactobacillus casei for stress reduction Supporting butyrate-producing bacteria fuels intestinal cells, improves lipid metabolism, and enhances oxidative muscle fibers for sustained aerobic performance Probiotics are most effective when introduced after gut healing, paired with a diet free from linoleic acid–rich vegetable oils and supported by prebiotic foods to maintain microbial balance

People who ate the most ultraprocessed foods had a 41% higher risk of developing lung cancer compared with those who ate the least The increased risk was seen in both smokers and nonsmokers, showing that diet alone influences lung cancer development Processed foods alter nutrient absorption, strip away protective compounds, and add toxic byproducts that fuel inflammation and immune dysfunction Harmful chemicals from packaging and high-heat cooking further raise cancer risk and weaken your body’s defenses Choosing whole, unprocessed foods and cutting linoleic acid in vegetable oils down to 2 grams or less daily is one of the most effective ways to protect your lungs

Low GABA levels are linked to anxiety, poor sleep, memory issues, and neurological conditions like epilepsy and Alzheimer’s, but boosting GABA through your gut microbiome offers a natural solution A study in NPJ Science of Food found that prebiotics like fructooligosaccharides (FOS) and Aspergillus-derived enzymes significantly increased brain GABA and homocarnosine, a compound that protects and stabilizes brain function Specific gut bacteria such as Akkermansia and Parabacteroides were directly linked to higher GABA production, while strains like Blautia and Roseburia were associated with lower levels and gut imbalance If your gut is inflamed, even healthy fibers worsen symptoms — so it's essential to start with low-fermentation carbs and reintroduce prebiotics slowly once digestion improves Strategies like fermented foods, GABA supplements, and natural progesterone further enhance GABA activity and support calm, clear, and stable brain function

A single can of cola floods your system with nearly 100% absorbable inorganic phosphate, triggering hormonal shifts that disrupt vitamin D, calcium balance, and kidney function Phosphate in soda raises levels of FGF23, a hormone that accelerates vascular calcification, weakens bones, and increases your long-term risk of heart attack or stroke, even if your labs are normal Unlike natural sources, phosphate additives in soda are rapidly absorbed and bypass digestive safeguards, placing a silent burden on your kidneys and arteries with every sip When combined with high-fructose corn syrup (HFCS), soda creates a metabolic double hit — HFCS promotes liver fat, raises uric acid, and drives insulin resistance, while phosphate sabotages hormonal and mineral balance Replacing soda with sparkling citrus water, magnesium glycinate, and vitamin K2 helps support your bones, protect your heart, and reverse the silent damage phosphate leaves behind

Sarcopenia, the age-related loss of muscle mass and strength, begins subtly in midlife and accelerates with age, increasing your risk of frailty, falls, and fractures As your body ages, muscles become less responsive to training, and physical gains come more slowly, even when effort and consistency remain the same A 2025 study published in Nature Communications found that older muscles fail to activate key growth pathways and repair signals after exercise, explaining the reduced adaptation Despite slower gains, exercise remains essential not just for physical strength but also for brain function, heart health, immune regulation, and metabolic resilience across the aging process Longevity benefits peak at around 40 to 60 minutes of strength training per week; exceeding this reverses the gains and increases the risk of overtraining

Most American adults live with a heart age older than their actual age, which silently raises the risk of heart disease, stroke, and early death long before symptoms appear On average, women’s hearts are about four years older than their bodies, while men’s are nearly seven years older, with many carrying a cardiovascular risk a full decade beyond their real age The burden of accelerated heart aging is heavier among people with lower income, less education, and minority backgrounds, widening health gaps across communities Researchers developed an online calculator that translates complex health data into an easy-to-understand “heart age,” helping you see if your heart is aging faster than the rest of your body You can take practical steps to rewind your heart age by eliminating vegetable oils, eating enough healthy carbs, walking daily, getting safe sun exposure, and testing for insulin resistance