A Breakthrough in Understanding Long COVID

People with long COVID experience persistent fatigue, breathlessness, and brain fog. Research links these effects to fibrin microclots intertwined with neutrophil extracellular traps that obstruct microvessels and impair oxygen delivery SARS-CoV-2 pushes blood into a hypercoagulable state, damaging endothelium, activating platelets, and inflammatory cytokines. This causes clot risk to persist for months, even after mild infections and hospital discharge Long COVID essentially boils down to mitochondrial dysfunction. Management includes proteolytic enzymes to help clear spike protein, while the I-RECOVER protocol guides detoxification, inflammation control, and mitochondrial repair to restore overall function Protecting cardiolipin, the mitochondrial membrane fat, requires limiting easily oxidized linoleic acid (LA) from seed oils, processed foods, nuts, seeds, and grain-fed meats Methylene blue may enhance mitochondrial respiration at low doses. Additionally, correcting copper deficiency and lowering excess iron through blood donation support energy production

A preliminary American Heart Association (AHA) study linked long-term melatonin use to increased heart failure risk, but a closer analysis shows serious flaws, including lack of peer review and failure to account for confounding variables The study found melatonin users had 90% higher heart failure rates, but data mixed together prescription-only countries with over-the-counter markets, misclassifying many actual users as non-users Moreover, the study failed to account for insomnia severity, psychiatric conditions, other medications, and dosing details, making it impossible to determine if melatonin caused the observed outcomes Decades of peer-reviewed research demonstrates melatonin's cardioprotective effects, including reducing blood pressure, protecting heart tissue, and mitigating oxidative damage, contradicting the study's alarming headlines While supplementation is unlikely to pose serious risks, there are natural ways to optimize your melatonin production, such as getting morning sunlight exposure, keeping a consistent sleep schedule, limiting evening blue light, eating earlier, and practicing stress-reduction techniques

A recent study reveals that bedroom ventilation plays an essential role in sleep quality. Carbon dioxide (CO₂) levels need to remain below 1,000 ppm, ideally under 800 ppm, for deeper, uninterrupted sleep Opening windows can help with airflow, but it's not always ideal due to outdoor pollutants, noise, or security risks. In such cases, a ventilation system is a safer and more reliable option Air purifiers filter indoor air but do not introduce fresh air. To maintain optimal air quality, pair filtration systems with proper ventilation rather than relying on one system alone Monitoring CO₂ levels in your bedroom helps ensure proper air exchange. Using a reliable CO₂ meter provides insight into ventilation efficiency and allows adjustments to improve sleep quality To further improve indoor air quality, regularly clean or replace air filters, minimize the use of synthetic air fresheners, scented candles, and harsh cleaning chemicals, opt for natural, nontoxic alternatives, and air out your home safely

Hot flashes occur when the hypothalamus becomes hypersensitive during menopause, triggering rapid blood vessel dilation and sweating. These vasomotor symptoms affect 80% of women and often persist for years A recent randomized clinical trial found that a six-week self-hypnosis program reduced menopausal hot flash frequency and severity by about 53%, with sustained improvements at 12 weeks About 90% of women using self-hypnosis reported noticeable relief, and those who practiced most consistently achieved the strongest reductions in hot flash frequency and daily interference The therapy was especially effective for breast cancer survivors, a group unable to use hormone-based treatments, producing a 64% reduction in symptom severity without adverse effects Beyond hypnosis, evidence also supports cognitive behavioral therapy to reduce how disruptive symptoms feel, relaxation practices to ease stress, and natural progesterone to help rebalance hormones during menopause

Diverticulitis, once considered a disease of aging, is now surging among adults under 50, with younger patients facing more severe and complicated cases than ever before Researchers from UCLA and Vanderbilt University found that early-onset diverticulitis hospitalizations rose sharply from 2005 to 2020, while procedures like abscess drainage more than doubled Younger adults have an 82% lower risk of death compared to older patients, but far higher odds of requiring invasive interventions — proof that the disease is becoming more disruptive, not less Processed foods, seed oils, chronic stress, and disrupted gut bacteria are key drivers of early inflammation in your colon, damaging your intestinal barrier and setting the stage for diverticulitis You can protect your gut by removing seed oils, eating easy-to-digest whole foods, rebuilding beneficial bacteria like Akkermansia, and supporting mitochondrial energy production to restore gut balance and long-term colon health

Migraines affect women three to four times more often than men, largely due to hormonal fluctuations that sensitize the brain's pain pathways and increase vulnerability to stress, poor sleep, and inflammation Estrogen both primes and triggers migraine attacks — high levels heighten sensitivity, while sudden drops before menstruation or after childbirth cause the electrical instability that sparks pain Natural progesterone helps counteract estrogen's pro-inflammatory effects, calming nerve excitability and reducing migraine frequency during hormonally active years Mitochondrial dysfunction is a major driver of migraines; reducing linoleic acid from seed oils and restoring nutrients like magnesium, CoQ10, and B vitamins strengthens your brain's energy supply and resilience Supporting melatonin through morning sunlight, minimizing blue light exposure at night, and maintaining oral and circadian health naturally lowers inflammation, helping prevent migraines and improve overall brain function

A healthy 47-year-old man from New Jersey suddenly died after delayed allergic reactions to red meat; it was later confirmed to be caused by alpha-gal syndrome (AGS), marking the first documented fatality linked to tick-driven mammalian meat allergy His symptoms began hours after eating beef following a recent camping trip, during which he sustained 12 to 13 suspected lone star tick bites — exposure to this tick is now known to trigger the immune sensitization that leads to AGS AGS occurs when the lone star tick introduces the alpha-gal sugar molecule into the bloodstream, causing the body to form antibodies and react severely, sometimes fatally, upon future consumption of mammalian meat or byproducts Cases of AGS are rising explosively across the United States, with documented diagnoses climbing from 12 in 2009 to more than 110,000 by 2022; estimates suggest over 450,000 Americans may be affected Experts warn that expanding tick ranges, misdiagnoses, and lack of awareness among healthcare providers are fueling this hidden public health threat, emphasizing the urgent need for preventive tick-bite strategies and proper tick removal techniques

Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic compounds built around extremely strong carbon-fluorine bonds. They're used to make products nonstick, waterproof, and stain-resistant A California biomonitoring study of 563 adults found that even low, detectable PFAS levels in public water systems were linked to 30% to 80% higher PFAS in blood PFAS aren't just in water — testing has found very high PFAS markers in soft contact lenses, wild freshwater fish, and some activewear leggings Health concerns linked to PFAS exposure include liver toxicity, immune and hormone disruption, cancer, high cholesterol, and developmental and reproductive effects You can reduce your personal exposure to PFAS by filtering your tap water, steering clear of most nonstick and stain-resistant products, and selecting PFAS-free personal care items

Nearly 90% of U.S. adults have at least one risk factor for cardiovascular-kidney-metabolic (CKM) syndrome, a newly named but long-standing health crisis that links heart, kidney, and metabolic dysfunction The American Heart Association warns that CKM often goes unnoticed until a major event like a heart attack occurs, yet most cases are reversible if identified early and addressed at the metabolic level Critics in PLOS Medicine argue that CKM is less a medical breakthrough and more a rebranding of what's already known — that mitochondrial failure, poor diet, and chronic stress drive the same interconnected diseases True recovery starts by repairing energy production in your cells: lowering linoleic acid intake, restoring magnesium balance, eating real carbohydrates, and supporting hormonal and circadian health through sunlight and rest By fixing mitochondrial function rather than chasing new labels, you help your organs work in sync again — stabilizing blood pressure, improving kidney filtration, and reigniting your metabolism from the inside out

New research shows that people with untreated sleep apnea experience a sharp nighttime drop in blood vessel function driven by the circadian system, increasing vulnerability to heart attacks and other cardiac events In a tightly controlled sleep-lab study, participants' arteries showed their worst ability to dilate around 3:00 a.m., revealing an 82% decline in vascular function during the biological night This impairment persisted even after adjusting for blood flow, sleep quality, and apnea severity, confirming the circadian system — not behavior or breathing events — directly weakens vascular health at night The findings help explain why people with sleep apnea experience more nighttime cardiac events, contrasting with the general population's morning peak in heart attacks and sudden cardiac death Researchers emphasize that understanding circadian timing may help refine cardiovascular treatments for sleep apnea patients, including optimizing medication schedules to enhance nighttime vascular protection