Stroke Alert April 2026

On Episode 63 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights articles from the April 2026 issue of Stroke, including "Integrating GFAP Testing With Clinical Scores for Prehospital Large Vessel Occlusion Detection in Patients With Acute Stroke (DETECT LVO)." She also interviews Dr. Aravind Ganesh on the article "Cerebral Amyloid Angiopathy Imaging Markers, Radiological Boston Criteria, and Thrombolysis Outcomes in Ischemic Stroke" and Dr. Dileep Yavagal on the article "Rescue Versus First-Line Intracranial Stenting During Thrombectomy for Acute Ischemic Stroke: A Propensity-Weighted Analysis of the RESISTANT Registry." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260409.820801

On Episode 62 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the March 2026 issue of Stroke: "Efficacy of Wearable Exoskeleton for Gait Recovery in Patients With Stroke: A Multicenter Randomized Controlled Trial" and "Switching From Aspirin Monotherapy After Noncardioembolic Stroke: A Systematic Review and Network Meta-Analysis." She also interviews Dr. Ángel Chamorro about the CHOICE2 trial, presented in February at the International Stroke Conference. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260317.356679

On Episode 61 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the February 2026 issue of Stroke: "Statin Use Is Not Associated With Reduced Cardio- and Cerebrovascular Hospitalizations in Older Adults With Dementia" and "Management Strategies for Early Neurological Deterioration in Noncardioembolic Ischemic Stroke." She also interviews Dr. Ashkan Shoamanesh about the OCEANIC-STROKE trial, presented this month at the International Stroke Conference. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260217.20096

On Episode 60 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the January 2026 issue of Stroke: "Impaired Perfusion and Early Ischemic Stroke Recurrence in Symptomatic Intracranial Atherosclerosis: BIORISK ICAS Study" and "Systematic Genetic Assessment in Young Patients With Cryptogenic Stroke: The ES-EASY project." She also interviews Dr. Fabiano Cavalcante and Prof. Charles Majoie about their article "Acute Carotid Stenting for Tandem Lesions in Patients Randomized to Endovascular Treatment With or Without Thrombolysis: Results From the IRIS Individual Participant Data Meta-Analysis." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20260114.701495

On Episode 59 of the Stroke Alert Podcast, host Dr. Negar Asdaghi is joined by Dr. Eva Mistry, Stroke Associate Editor and Vice Chair of Research and Divisional Director of Vascular Neurology at the Department of Neurology and Rehabilitation Medicine at the University of Cincinnati, for the 2025 Ralph Sacco Review of Top Cerebrovascular Research. In honor of the late Dr. Ralph L. Sacco, former Editor-in-Chief of Stroke, who died in January 2023, Drs. Asdaghi and Mistry review some of the top cerebrovascular science published in any journal or presented at any scientific forum throughout the past year. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251216.704704

On Episode 58 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the November 2025 issue of Stroke: "Fingolimod as a Potential Cerebroprotectant Results From the Stroke Preclinical Assessment Network" and "Apixaban and Recurrent Stroke Risk With Left Ventricular Dysfunction: A Secondary Analysis of the ARCADIA Trial." She also interviews Drs. Aaron Rodriguez-Calienes and Santiago Ortega-Gutierrez about their article "Endovascular Thrombectomy Versus Best Medical Therapy for Large Vessel Occlusion Stroke Beyond 24 Hours: A Systematic Review and Meta-Analysis." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251114.13070

On Episode 57 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the October 2025 issue of Stroke: "Oxygen Extraction Fraction on Baseline MRI Predicts Infarction Growth in Successfully Reperfused Patients" and "Tadalafil Treatment in Patients With Cerebral Small Vessel Disease: The ETLAS-2 Randomized Clinical Trial." She also interviews Dr. Thomas Meinel on the article "Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251008.578434

On Episode 56 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the September 2025 issue of Stroke: "Glucagon-Like Peptide-1 Receptor Agonists and Risk of Nontraumatic Intracerebral Hemorrhage in Patients With Type 2 Diabetes" and "White Matter Hyperintensity Multispot Pattern Lesions and Cerebrovascular Amyloid Burden in Cerebral Amyloid Angiopathy." She also interviews Dr. Cora Nijboer and Prof. Manon Benders on their article "Perinatal Arterial Stroke Treated With Stromal Cells Intranasally: 2-Year Safety and Neurodevelopment." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250910.502300

On Episode 55 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the August 2025 issue of Stroke: "Anticoagulation Timing in Acute Stroke With Atrial Fibrillation According to Chronic Kidney Disease: The OPTIMAS Trial" and "Risk of Intracranial Hemorrhage With Apixaban Versus Aspirin Therapy: A Meta-Analysis of Randomized Controlled Trials." She also interviews Dr. Stephen Ryan and Prof. Anne Aamodt about the Tenecteplase in Central Retinal Artery Occlusion Study (TenCRAOS), presented in May at the European Stroke Organisation Conference. For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250815.784085

On Episode 54 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the July 2025 issue of Stroke: "Association of the Timing and Type of Acute Symptomatic Seizures With Poststroke Epilepsy and Mortality" and "Effect of Argatroban Plus Dual Antiplatelet in Branch Atherosclerosis Disease: A Randomized Clinical Trial." She also interviews Dr. Amrou Sarraj about the article "Mechanical Thrombectomy for Large Ischemic Stroke: A Critical Appraisal of Evidence From 6 Randomized Controlled Trials." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250710.454589