211 A Groundbreaking Discovery for Balancing the Immune System in Hashimoto’s With Michael Antonelli

Hashimoto’s is often treated as a thyroid problem. But in reality, it is a problem of immune confusion. When the immune system loses tolerance and begins reacting to the body’s own tissues, inflammation and symptoms follow.In this conversation, Inna Topiler sits down with Michael Antonelli to explore a fascinating area of emerging research that may change how we think about immune regulation in Hashimoto’s. Instead of trying to stimulate or suppress the immune system, the focus shifts to something much more intelligent, helping the immune system regain balance and recognize what truly belongs in the body.Michael shares research on human-equivalent lactoferrin, a bioactive compound inspired by breast milk that appears to play a role in gut signaling, iron balance, and immune communication. The science behind it opens an interesting window into how the gut and immune system interact, and why restoring the right signals may be just as important as removing triggers.This conversation brings together gut health, immune regulation, and the deeper idea of helping the body restore its own internal intelligence. When the immune system learns to communicate clearly again, many of the patterns behind autoimmune symptoms begin to make more sense.You can see much more about Human Mimicking Lactoferrin here and use code “RESTORE” to get 10% off.For full show notes, please see:https://innatopiler.com/podcasts/balancing-immune-system-hashimotos-michael-antonelli/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping If you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcallFor more information about everything Hashimoto’s please visit InnaTopiler.com

In this episode, I am joined by Dr. Shivani Gupta to talk about Ayurveda, inflammation, and what this 5,000 year old system of medicine reveals about Hashimoto’s and thyroid health.There are moments in clinical practice where you realize the conversation around inflammation has been too narrow. We measure antibodies. We look at gut markers. We talk about nutrients. But there is another layer that often gets overlooked, the way daily rhythm and nervous system patterns shape immune behavior.Ayurveda does not separate digestion from stress or stress from immune signaling. It looks at the entire terrain. It asks how your constitution influences the way you burn through energy, hold onto it, or stagnate it. It challenges the idea that everyone should follow the same rules for healing.What I appreciate about this discussion is that it does not add complexity. It adds perspective. It reframes inflammation as something influenced by pace, timing, and consistency, not just inputs.If you have ever felt like you were doing everything on paper and still missing something deeper, this episode will help you see your thyroid in a more integrated way.For full show notes, please see:https://innatopiler.com/podcasts/ayurveda-inflammation-hashimotos-thyroid-dr-shivani-gupta/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping If you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcallFor more information about everything Hashimoto’s please visit InnaTopiler.com

You can follow a solid protocol for Hashimoto’s and still feel like something is not fully clicking.Your labs may look better. Your inflammation markers may improve. But your body still feels braced, wired, or unable to truly settle.In this episode, Inna sits down with Dr. Karyn Shanks to talk about a layer of healing that rarely gets addressed, hypervigilance.We explore how overfunctioning, overworking, and constantly being on can become a stress pattern that keeps cortisol elevated and the immune system reactive. Not because you are failing, but because your nervous system has learned to stay alert.You will see how sensations like throat tightness, chest constriction, or a constant sense of urgency are not random. We talk about the difference between a sensation and the story your brain builds around it, and why giving a feeling space for even ninety seconds can shift your physiology.We also discuss trauma informed care, why safety has to come before deeper healing, and how overdoing can be tied to worthiness and performance rather than true resilience.Healing is not only biochemical. It is also nervous system regulation, emotional awareness, and learning when to say yes and when to say no.This episode will help you look at your thyroid healing through a wider lens and understand what might still be keeping your body on guard.For full show notes, please see:https://innatopiler.com/podcasts/hashimotos-protocol-karyn-shanks/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping If you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcallFor more information about everything Hashimoto’s please visit InnaTopiler.com

There is a point many people with Hashimoto’s reach where exercise becomes a constant question mark. You are moving your body, trying to be consistent, and still wondering if you are doing too much, not enough, or the wrong kind altogether.This conversation with Inna Topiler and Angela Brown sits right inside that uncertainty. The space between being told to push harder and starting to wonder if pushing harder is exactly why your body feels the way it does. They talk about why exercise can feel so confusing with Hashimoto’s and why so many people end up second-guessing themselves instead of trusting what they are noticing.As the conversation unfolds, you will start to see how different types of exercise affect the Hashimoto’s body in very different ways. You will hear how to think about recovery, fatigue, inflammation, and weight changes together, instead of as separate problems, and why what happens after your workout often matters more than how you feel during it.You will also see exactly how to tell whether the exercise you are doing is actually working for you, when it may be time to change your approach, and how to start making those decisions without swinging between doing nothing and doing too much. For full show notes, please see:https://innatopiler.com/podcasts/exercise-hashimotos-fatigue-weight-gain-angela-brown/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training atInnaTopiler.com/zoomcall

Cooking with Hashimoto’s often becomes the hardest place to stay consistent, not because you do not know what foods are supportive, but because figuring out how to cook in real life takes energy, planning, and the right setup.In this conversation Inna and Hypothyroid Chef Ginny Mahar talk about how to actually cook in a way that supports your body without turning food into another source of stress. You will see how anti inflammatory eating looks in real life, why personalization matters, and how to think about meal prep, leftovers, freezing, and cooking methods in a way that preserves energy instead of draining it.The episode also goes beyond food and into the kitchen itself, from pots and pans to utensils, cutting boards, and food storage. If cooking with Hashimoto’s has felt overwhelming or unrealistic, this conversation will help it feel simpler, calmer, and more doable.For full show notes, please see:https://innatopiler.com/podcasts/cook-hashimotos-hypothyroid-chef-ginny-mahar/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

Weight loss with Hashimoto’s often feels harder than it should, even when you’re doing all the things. This episode explores why that frustration is so common and why most weight loss advice doesn’t fully apply to a Hashimoto’s body.In this conversation, Inna explains how weight loss with Hashimoto’s follows a different set of rules and why understanding that difference changes how you approach food, metabolism, and progress.If weight loss has felt confusing, inconsistent, or resistant, this episode will help you see it through a very different lens.And if you want a clear step by step process so you can implement everything the right way and lose weight with Hashimoto’s, please check out the 10 Day Hashimoto’s Weight Loss Transformation at https://innatopiler.com/jumpstart/

So many people with Hashimoto’s carry emotional patterns they don’t even realize are affecting their thyroid. Today we take a closer look at the invisible habits we learn early in life, the ones that quietly shape how safe we feel being ourselves.Sometimes you minimize what hurt you. Sometimes you feel responsible for other people’s reactions. Sometimes you stop trusting your own knowing, even when your body is nudging you in the right direction. These patterns may seem emotional on the surface, but they create real physiological stress, and your thyroid feels every bit of it.This episode explores why these habits form, how they show up in everyday situations, and why the thyroid is uniquely sensitive to self-expression, boundaries, and inner trust. You will see how simple shifts in awareness can help your body feel safer, calmer, and more supported from the inside out.If you have ever felt like you disappear inside your own life, or like your voice gets quieter when you need it most, this conversation will help you reconnect to yourself in a deeper way. Your thyroid responds to that connection, and you may be surprised how much changes when you begin to honor what you truly feel.Healing is not only biochemical, it  is also emotional, energetic, and rooted in how you relate to yourself every day. For full show notes, please see:https://innatopiler.com/podcasts/thyroid-labs-hashimotos/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

There is always a deeper story behind emotional eating, and in this episode Inna and guest Lisa Schlosberg open up the layers most people never connect to food. They explore the moments when you eat without hunger, the childhood patterns that shaped your sense of safety, and the reasons your body may turn to food even when your mind insists you are “fine.” What begins as a conversation about eating quickly becomes a conversation about emotional wiring, nervous system responses, and the parts of you that learned to cope long before you had words for it.Lisa shares her own experience of losing 150 pounds and discovering that the harder work had nothing to do with calories or willpower. It was learning how to feel feelings she spent years avoiding. It was realizing food had been her protection, her comfort, and her armor. Together, she and Inna talk about why emotional hunger feels real, why you can’t solve an emotional problem with a physical solution, and how self compassion and internal safety begin to shift lifelong patterns around eating.They also explore the small, often unnoticed triggers that shape your relationship with food. Clean plate conditioning. Scarcity wiring. Eating in front of screens. The need for stimulation. The pull toward comfort when you are overwhelmed. The instinct to stay “strong” at the cost of your own emotional expression. And for many with Hashimoto’s, the way growing up without validation creates a lifelong habit of seeking comfort and reassurance outside of yourself.This episode is a grounded, deeply human look at emotional eating, inner safety, and the process of gently rewriting the relationship you have with food. It brings together mind, body, and emotion in a way that will help you understand yourself on an entirely new level.For full show notes, please see:https://innatopiler.com/podcasts/eating-not-hungry-relationship-food-lisa-schlosberg/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

Fasting is everywhere these days, but most traditional fasting approaches are too harsh when you have Hashimoto’s. Long stretches without food can feel destabilizing, draining, and completely unrealistic for a thyroid that is already under stress. However there is a different approach called fasting mimicking that creates the deeper cellular benefits of fasting while you are still eating real food. Fasting mimicking has been heavily researched for decades and is designed to activate the same fasting pathways that support things like metabolism, energy, longevity, and overall cellular renewal. Instead of pushing the body into stress, it uses precise nutrients that keep the fasting response going while still providing nourishment, which makes it far more compatible with the needs of someone living with Hashimoto’s. It also offers an approachable way to support weight, inflammation, and metabolic health without cutting calories to extremes or spiking cortisol.This is the kind of information that changes how you think about fasting altogether and incredibly relevant if regular fasting has ever made you feel worse instead of better. This episode is a must listen, and if you want to try fasting mimicking for yourself, you can do that here and please use code "FASTING" for 20% OFF!For full show notes, please see:https://innatopiler.com/podcasts/203-fasting-thyroid-hashimotos-renee-fitton/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training atInnaTopiler.com/zoomcall

Your surroundings can either calm your body or keep it in constant overdrive. In this episode, HGTV designer Sabrina Soto shares how the way we organize, decorate, and even rest inside our homes directly affects the nervous system and thyroid health.Sabrina opens up about her own turning point, from a safe but unfulfilling career to creating a life and home designed with intention, and how that same mindset applies to healing. You’ll hear how clutter impacts cortisol, why your bedroom setup matters more than you think, and how small, thoughtful changes can bring more calm, clarity, and energy back into your day.This conversation blends design and wellness in a way that feels deeply practical. From simple systems that make life lighter to letting go of energy leaks that drain you, Sabrina shows how creating supportive spaces is one of the most overlooked forms of healing with Hashimoto’s.For full show notes, please see:https://innatopiler.com/podcasts/design-home-support-thyroid-hashimotos-sabrina-soto/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training atInnaTopiler.com/zoomcall