Chris Sander, Professor for Cell Biology from Harvard Medical School and one of the founders of bioinformatics, works to understand the "labyrinth" of cancer growth. The aim of his current research as an Einstein Visiting Fellow at the Berlin Institute of Health is to find out how to block the side doors through which aggressive cancer types manage to escape medical blockage during a treatment. Sander uses machine learning to analyze clinical records and predict how cells react on certain perturbances, or to identify risk patients. Starting his career as a physicist, it took him some turns to get where he is today. His advice for young researchers: stick with science, look for mentors - and ask the right questions.
Weitere Episoden von „#AskDifferent“
#27 ManyBabies5: Inside a Baby’s Mind
27:01What is going on in babies’ minds? What do they think and feel? Jessica Kosie and Martin Zettersten are not only looking for answers to these questions – they are cooperating with more than 200 scientists in 40 countries to define the fundamentals needed to establish research globally. The challenges they face are not easy to solve: Since babies are unable to speak, they cannot answer our questions directly. In this episode of #AskDifferent, the Einstein Foundation Award 2021 winners talk about finding ways around that obstacle, what we can learn from studying babies’ attention, their gazes and preferences, and how parents and adults can benefit from that knowledge.
#26 Riccardo Giovanni Urso: Is there life in space?
26:03Are we alone in space? What could extraterrestrial life forms look it? And how do we find them? These questions are almost as old as mankind itself. Natural Scientist and former Einstein International Postdoctoral Fellow Riccardo Giovanni Urso tries to answer them every day. In this episode of #AskDifferent, he talks about his scientific journeys through space, basic ingredients for life, and why he would love to be onboard a mission to mars.
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#25 Paul Ginsparg: The godfather of open access publishing
25:49Preprints have been circulated in the physics community since the early 1950s but mostly among well-established professors. Physicist Paul Ginsparg, who received the inaugural Einstein Foundation Award for Promoting Quality in Research in the Individiual Award category, set out to democratize access to scientific results. Today, his preprint server arXiv accommodates a broad array of fields — and has made scientific progress more efficient and fairer. In this episode, he reflects on his motivation to create arXiv.org back in 1991, the ways it has changed and continues to change scientific processes today, and the fact that freely shared scientific knowledge can encourage young people to become scientists.
#24 Anna Löwa: Bleibt kreativ!
26:25Mini-Organe aus der Petrischale: Die Biotechnologin Anna Löwa beschäftigt sich in ihrer Forschung mit sogenannten Organoiden, speziellen Zellkulturen beispielsweise des Gehirns oder der Lunge. Diese Organoide können die Strukturen und Funktionen einzelner Organe darstellen und damit einen Zugang zur Erforschung und Behandlung menschlicher Erkrankungen ermöglichen. Die junge Wissenschaftlerin ist Postdoc am Einstein-Zentrum 3R für alternative Methoden in der biomedizinischen Forschung. Das Zentrum will die Übertragbarkeit von Laborerkenntnissen auf den Patienten verbessern und damit gleichzeitig den Tierschutz stärken. Um kreativ zu bleiben, rät sie jungen Forschenden und Studierenden, regelmäßig die Perspektive zu wechseln und bewusst vom Forschungsprojekt Abstand zu nehmen.
#23 Bertil Tungodden: How to Make a Difference
27:20Can behavioral economics change the world? Yes, thinks Bertil Tungodden, Research Director at the Centre for Experimental Research on Fairness, Inequality, and Rationality in Bergen and Einstein Visiting Fellow at the Humboldt University. His comparative studies aim at explaining why people have a different idea of when existing inequalities are actually unfair. In this episode, he gives insight into the experiments he designs to find out about the norms & values underlying decision making – and explains why, by the effects of his research, he can make a little difference.
#22 Britta Tietjen: Wenn die Spree rückwärts fließt
24:45Mancherorts ist der Wasserstand der langsam fließenden Spree so niedrig, dass sie gar ihre Laufrichtung ändert: Eins von vielen Beispielen, an denen die Ökologin Britta Tietjen erklärt, wie es um die Ressource Wasser in Berlin-Brandenburg steht. Als Sprecherin der Einstein Research Unit "Climate and Water Under Change (CliWaC)" modelliert Tietjen mögliche Zukunftsszenarien von regionalen Ökosystemen. Bei der Suche nach Antworten auf zunehmende Dürren und Starkregen bezieht das Projekt auch Politiker*innen, städtische Betriebe und andere Betroffene ein. Sei die schleppende Bekämpfung des Klimawandels auch schwer zu ertragen, verliert Tietjen nicht ihre Freude an der Forschung und die Hoffnung, "dass Wissenschaft und Bevölkerung zusammenkommen". Die Einstein Stiftung nimmt mit diesem Beitrag am Fast Forward Science Wettbewerb 2022/2023 teil: https://fastforwardscience.de/ #AudioSpezial
#21 Andrew Hurrell: Brave Old World
24:40Everyone is familiar with globalization, its problems and discontents. But how to correspond to it politically? Andrew Hurrell is Professor of International Relations at the University of Oxford and has spent much time studying liberal ideas about globalization: how it has evolved in modern times as well as its current challenges like populism, pandemics, climate change, and war. As an Einstein Visiting Fellow at the Cluster of Excellence "Contestations of the Liberal Script (SCRIPTS)", Andrew Hurrell seeks to understand why adopting truly internationalist policies is so difficult today; why the old world order of power politics has returned, and how geopolitics might be tamed in favour of new models of multilateral cooperation. Please note: The interview was recorded in 2021, months before the Russian invasion of Ukraine.
#20 Chris Sander: Mapping the Labyrinth
24:52Chris Sander, Professor for Cell Biology from Harvard Medical School and one of the founders of bioinformatics, works to understand the "labyrinth" of cancer growth. The aim of his current research as an Einstein Visiting Fellow at the Berlin Institute of Health is to find out how to block the side doors through which aggressive cancer types manage to escape medical blockage during a treatment. Sander uses machine learning to analyze clinical records and predict how cells react on certain perturbances, or to identify risk patients. Starting his career as a physicist, it took him some turns to get where he is today. His advice for young researchers: stick with science, look for mentors - and ask the right questions.
#19 Dorothy Bishop: Overcoming Our Biases
27:59Careful work and self-criticism is not rewarded enough in today's accelerated research culture, Dorothy Bishop thinks. A jury member of the 2021 Einstein Foundation Award for Promoting Quality in Research, the Professor of Developmental Neuropsychology at the University of Oxford advocates for evidence-driven, open science practices and a new incentive structure. As a psychologist, she studied specific language impairments in children and showed that some of the disposition is genetic, which helped to get rid of the misconception that merely parents are to blame when a child is struggling with speach. In the interview, the experienced teacher and mentor shares her ideas how to increase public trust in science and encourages every scholar who encounters systemic problems to try and change them.
#18 Vittorio Gallese: We Are Relational Beings
31:15As a social neuroscientist, Vittorio Gallese has a unique understanding of how we live together. Until recently, he headed a research group at the Berlin School of Mind and Brain focusing on the development of socio-cultural identities. Back in Italy, the Professor of Psychobiology from Università di Parma, who is widely known for his discovery of mirror neurons, continues to explore the cognitive structures of empathy and sympathy. In addition, he is interested in how the brain adapts to life in the pandemic. For #AskDifferent, we spoke about the lockdown experience, the ambivalences of digital media, and the role of effort and coincidence in scientific breakthroughs.