ASCENT and DESTINY-Breast09 Trials: Applying Frontline Data in Metastatic Breast Cancer Care

Dr. Sara Tolaney joins Dr. Monty Pal to discuss optimizing the sequencing and combination of antibody-drug conjugates for metastatic HER2-positive and triple-negative breast cancer, as well as guidelines for managing serious toxicities like ILD and neutropenia. LINK TO FULL TRANSCRIPT

Myeloma specialists Dr. Marc Braunstein and Dr. Rahul Banerjee join Dr. Monty Pal to discuss recent breakthroughs for patients with multiple myeloma, including expert advice on how to manage side effects and identify the right treatment among a series of novel immuno- and targeted therapies. LINK TO FULL TRANSCRIPT

Dr. Jedd Wolchok, a pioneer in melanoma research, joins Dr. Monty Pal to break down practice-changing advances in the field, including landmark 10-year CheckMate-067 survival data, safer immunotherapy dosing, and the rise of neoadjuvant treatment. LINK TO FULL TRANSCRIPT  

Dr. Monty Pal and Dr. Petros Grivas discuss the rapidly evolving management of bladder cancer, including key updates in non-muscle-invasive disease, the integration of novel therapies in the advanced setting, and practical strategies for managing toxicities in clinical practice. LINK TO FULL TRANSCRIPT

In part two of our miniseries on the global translation gap in oncology, host Dr. Monty Pal and Dr. Regina Barragán-Carrillo explore how ASCO26 Plenary breakthroughs can be adapted to clinical practice in Latin America. Together, they address real-world implementation challenges including delayed diagnoses, finite resource allocation, and access to precision diagnostics. LINK TO FULL TRANSCRIPT

Dr. Monty Pal and Dr. Rachna Shroff explore how GLP-1 receptor agonists impact progression and survival in GI cancers, examining current retrospective data, immune microenvironment biology, and the need for prospective trials. LINK TO FULL TRANSCRIPT

How do we translate oncology breakthroughs into practice? In part one of a two-part miniseries, host Dr. Monty Pal and Dr. Atul Batra discuss the clinical realities, opportunities, and challenges of adapting ASCO26 Plenary findings into cancer care worldwide, using India's health care landscape as a blueprint for resource-limited settings. LINK TO FULL TRANSCRIPT  

Dr. Monty Pal and Dr. Roselle De Guzman discuss key abstracts from the 2026 ASCO Breakthrough Meeting, including the real-world impact of liquid biopsies for early multi-cancer detection, AI applications in colorectal cancer screening, and how global advances in breast, esophageal, and small cell lung cancers translate directly to diverse patient populations in the Asia-Pacific region. LINK TO FULL TRANSCRIPT

Dr. Megan Kruse and Dr. Hope Rugo discuss practice-changing data in metastatic breast cancer and critical shifts in the treatment of early-stage disease that were presented at the 2026 ASCO Annual Meeting. LINK TO FULL TRANSCRIPT

Dr. Neeraj Agarwal and Dr. Jeanny Aragon-Ching discuss high-impact abstracts in the treatment of prostate, bladder, and kidney cancers that were presented at the 2026 ASCO Annual Meeting. LINK TO FULL TRANSCRIPT