492 | Dr. Damon Forbes | Understanding Lean Mass Hyper-Responders

Dr. Erin Faules speaks with Dr. Damon Forbes about Lp(a), a genetically influenced lipoprotein linked to cardiovascular disease risk. They discuss how Lp(a) differs from LDL, its role in plaque and clotting, and why a one-time test can help clarify long-term risk. The conversation covers who to screen and when, interpreting Lp(a) alongside apoB and metabolic health, evidence-based ways to lower overall cardiovascular risk, and emerging Lp(a)-lowering therapies

Dr. Erin Faules speaks with Ashleigh Di Lello, creator of Bio Emotional Healing®, about how trauma, stress, and chronic illness can reshape the nervous system and how the brain's capacity to rewire itself supports recovery. They discuss the science of neuroplasticity, the connection between belief and biology, and practical ways to move the body out of chronic stress toward restoration and balance.

Dr. Jeff Graham speaks with Dr. Danny Firth, a Wild Health physician who transitioned from hospital-based medicine to precision and integrative care. They explore what led him to leave reactive "sick care" for a preventive, data-driven approach using genomics, biomarkers, and lifestyle to keep patients healthy before disease develops. Dr. Firth also shares how he balances work, family, and personal wellness while practicing what he teaches.

Dr. Jeff Graham talks with Dr. Mattias Bernow, a physician, economist, and CEO of Cellcolabs — about the current state of stem cell therapy. They discuss how mesenchymal stem cells (MSCs) function through signaling rather than cell replacement, where evidence supports their use today, and why good manufacturing practices (GMP) are essential for safety and efficacy. The conversation explores clinical data on cardiovascular, autoimmune, and neurodegenerative diseases, and what large-scale, evidence-based production could mean for the future of regenerative medicine.

Dr. Erin Faules and longevity expert Nathalie Niddam discuss how peptides and bioregulators can help the body maintain equilibrium at the cellular level. They unpack how these small protein molecules influence signaling and gene expression, the difference between supporting adaptation versus overstimulation, and how thoughtful use of these tools fits into a holistic approach to health and aging.

Dr. Jeff Graham sits down with Dr. Damon Forbes to explore the emerging concept of "lean mass hyper-responders"— fit, low-carb individuals who present with unusually high LDL levels. They unpack the physiology behind this pattern, discuss how it differs from familial hypercholesterolemia, and review new data on cardiovascular risk. The conversation offers a nuanced look at how metabolism, diet, and lipid transport intersect in precision medicine.

In this episode, Dr. Erin Faules speaks with Joel Greene, author of The Immunity Code, about the importance of balance and adaptability in human health. They discuss how real-world factors—time, context, and individual biology—shape sustainable nutrition and fitness strategies. From cycling foods and supplements to aligning with circadian and weekly rhythms, Greene explains how physiological balance supports metabolic health, microbiome diversity, and longevity.

Dr. Tommy Wood, physician-scientist and professor of pediatrics and neuroscience at the University of Washington, shares how the brain develops, adapts, and recovers from injury across the lifespan. He explains how genetics, exercise, nutrition, sleep, and other daily habits shape cognitive performance and resilience. Drawing on research and clinical insights, Dr. Wood highlights practical, evidence-based strategies to support brain health at every stage of life.

This episode features health coach and nurse Michele Miller in conversation with Dr. Erin. They discuss why eating less isn't always the path to better health, how metabolism adapts to prolonged calorie restriction, and the concept of "reverse dieting"—gradually increasing food intake to support energy, hormone balance, and body composition. The conversation emphasizes practical strategies, like eating breakfast and fueling around exercise, while addressing common fears about eating more.

Can your grip lower your blood pressure? In this episode, Dr. Erin Faules talks with Mark Young, CEO of Zona Health, about how isometric training can support cardiovascular health and help manage blood pressure without medication. We also cover early detection, self-monitoring, and nervous system regulation in protecting healthspan and preventing chronic disease. Topics covered: The Air Force origins of isometric training research How isometric exercise improves vascular health and lowers blood pressure Using data and self-tracking for early detection of dementia and heart disease The role of inflammation and nervous system balance in longevity