Decoding the Immune Response to Tuberculosis

Stephen Carpenter, MD, PhD, discusses the challenges of preventing and treating TB as well as the limitations of current vaccines, the role of memory T cells in controlling infection, and promising discoveries that could shape the next generation of tuberculosis vaccines. Learn more about Daniel Simon, MDLearn more about Stephen Carpenter, MD, PhDView our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

University Hospitals Reproductive Endocrinology and Infertility specialists, Rebecca Flyckt, MD, and Kathryn Coyne, MD, discuss a groundbreaking FDA-approved clinical trial exploring ovarian tissue transplantation between sisters. They explain how the procedure works, who may benefit and how this innovative approach could restore fertility, hormone function and hope for women facing early menopause.Learn more about Daniel Simon, MDLearn more about Rebecca Flyckt, MDLearn more about Kathryn Coyne, MDView our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Discover how a target identified in colon cancer research led to an unexpected opportunity to protect brain cells and preserve cognition in mouse models of Alzheimer’s and head trauma. Sanford Markowitz, MD, PhD, and Andrew Pieper, MD, PhD, describe the translational path, mechanistic insights into neuroinflammation and neurogenesis, and what’s needed for human trials.Learn more about Daniel Simon, MDLearn more about Andrew Pieper, MD, PhDLearn more about Sanford Markowitz, MD, PhDView our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Adonis Hijaz, MD and Goutham Rao, MD discuss the reasons why urinary incontinence is underreported and actionable strategies clinicians can use to start the conversation in primary care. They outline the EMPOWER model, from large-scale screening to nurse navigators and pelvic floor physical therapy, and why that pathway increases treatment rates. Learn more about Daniel Simon, MDLearn more about Adonis Hijaz, MDLearn more about Goutham Rao, MDView our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Explore the rapidly evolving world of CAR T-cell therapy and how scientists are reengineering the immune system to fight disease. Drs. David Wald and Reshmi Parameswaran discuss breakthroughs in cancer immunotherapy, including faster manufacturing, next‑generation CAR T-cell design, and efforts to expand these therapies from blood cancers to solid tumors and autoimmune diseases. This conversation highlights the promise and challenges of bringing these innovative treatments to patients. Learn more about Daniel Simon, MD Learn more about David Wald, MD, PhD Learn more about Reshmi Parameswaran, PhD, MS View our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

The pace of change in cardiometabolic medicine is accelerating. Ian Neeland, MD, breaks down the latest innovations in incretin therapies, from oral medications to cutting-edge combinations, and what they mean for weight loss, heart health, and long-term patient care.Learn more about Daniel Simon, MDLearn more about Ian Neeland, MDView our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Matthew Anderson, MD, PhD, and Tyler Miller, MD, PhD, discuss how immune biology is reshaping neuroscience - from autism and obesity to CAR T cell therapies for glioblastoma and the challenge of crossing the blood brain barrier.Learn more about Daniel Simon, MDLearn more about Matthew Anderson, MD, PhDLearn more about Tyler Miller, MD, PhDView our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Jennifer Villwock, MD, explains the neurocircuitry of smell, her rapid essential-oil–based AROMA test, and how olfactory dysfunction can inform clinical care and research spanning sinonasal disease, post-viral loss, and cognitive health.Learn more about Daniel Simon, MDLearn more about Jennifer Villwock, MDView our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Molly McVoy, MD, dives into the mental health crisis affecting teens, why anxiety and depression have risen dramatically, and shares breakthrough research using EEG biomarkers and self-management programs that help teens build resilience. Learn more about Daniel Simon, MDLearn more about Molly McVoy, MDNEW! View our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Theodoros Teknos, MD, and Gary Schwartz, MD, discuss how the recent $25.5 million NCI grant renewal solidifies Case Comprehensive Cancer Center as a powerhouse consortium delivering cutting-edge clinical trials, early detection and community-focused cancer prevention across Northeast Ohio.Learn more about Daniel Simon, MDLearn more about Theodoros Teknos, MDLearn more about Gary Schwartz, MDNEW! View our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute