Dr. Florence Comite: The 5 Biomarkers Every Midlife Woman Must Test | #156

  Get Dr. Vonda's insights Want to understand what's happening in your body — and what to do next? Each week, Dr. Vonda shares science-backed guidance on strength, bone health, muscle, and longevity — the same way she speaks to her patients. Clear. Practical. No noise. Join the newsletter: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3& I sat down with Dr. Florence Comite, the original gangster of precision medicine, who has been treating every patient as an "N of 1" for over 30 years. She pioneered Women's Health at Yale in 1992 and has spent her career proving that your genes are not your destiny. We go deep into what it actually takes to reverse biological aging, not slow it, reverse it. What we cover: - The five biomarkers that are suboptimal in nearly every patient, and why your doctor is probably not testing all of them. - Why "normal" lab values are not the same as optimal, and how that gap is silently costing you your health. - Why testosterone is the most underprescribed hormone in women's health, and what you lose without it. - How epigenetics means your lifestyle is rewriting your genetic destiny every single day. Why sleep, not exercise, is the foundation everything else is built on. About Dr. Florence Comite: Florence Comite, MD, physician-scientist, endocrinologist, and global authority on healthy longevity, is founder of the Comite Center for Precision Medicine & Healthy Longevity in New York, Palo Alto, and Miami Beach. A Yale School of Medicine graduate and faculty member for twenty-five years, Dr. Comite held triple appointments in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology). As a clinical investigator, she developed research and patented therapies at the National Institutes of Health (NIH) and Yale. In 1992, she pioneered the nation's first center for women's health at Yale, redefining integrative care for women. Dr. Comite also founded the first physician-led artificial intelligence app. Trained on decades of her proprietary real-world research, it's a powerful personalized tool to help people optimize their healthspan. Connect with Dr. Florence Comite: Website: www.comitemd.com Instagram: https://www.instagram.com/drflorencecomite/ LinkedIn: https://www.linkedin.com/in/drflorencecomite/ TikTok: https://www.tiktok.com/@drflorencecomite/ X (Twitter): https://x.com/FlorenceComite 📗 Invincible: Defy Your Genetic Destiny to Live Better, Longer by Dr. Florence Comite This is the book for anyone who refuses to accept that decline is inevitable. Preorder the book at your favorite online bookseller: https://www.theinvinciblebook.com/ Timestamps 00:00 Intro 01:46 You Are an N of 1 05:58 Hormones as Master Communicators 09:28 The 5 Biomarkers Everyone Gets Wrong 14:23 Normal vs. Optimal 18:27 What Wearing a CGM Will Teach You About Yourself 22:24 The Thrifty Gene Theory 27:29 Testosterone in Women 32:12 Birth Control Pills and Bone Loss 37:00 How Lifestyle Rewrites Your Genes 40:30 Intermittent Fasting and GLP-1s 43:14 Do Biological Age Tests Actually Work? 46:10 Sleep Is the Foundation 49:28 Making Precision Medicine for Everyone Start your Unbreakable journey Most women are never given a clear plan for how to stay strong as they age. The Unbreakable Lifestyle is where that changes. This is the home of Dr. Vonda's method — built from 20+ years of clinical work and designed for real life. Inside: - Unbreakable Assessment — know exactly where you stand - Training plans — build muscle, protect bone, improve performance - AI Dr. Vonda — get answers and guidance anytime - Community — women committed to staying strong and engaged - Exclusive education — what actually works, all in one place This is not another program. This is how you build strength — with direction. Join the Unbreakable Lifestyle: https://www.theunbreakablelifestyle.com/ Build stronger bones Bone loss starts earlier than you think — and speeds up in midlife. Dr. Vonda's Unbreakable Bone Health formula supports bone density, strength, and long-term skeletal health with clinically researched ingredients. Foundational. Not optional. Shop now: https://shop.drvondawright.com/?utm_s   Read the book Unbreakable: A Woman's Guide to Aging with Power A clear, science-backed roadmap to building strength, supporting your body, and taking control of how you age. Get your copy: https://theunbreakablebook.com?utm_so    About Dr. Vonda Wright Dr. Vonda Wright is an orthopedic sports surgeon and leading expert in women's health and longevity. For over 20 years, she has helped women build muscle, strengthen bone, and extend their health span — with science, not guesswork. Her mission is simple: help women age with power.   Connect with Dr. Vonda Instagram: https://www.instagram.com/drvondawright Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://manage.kmail-lists.com/subscriptions/subscribe?a=YqJKtR&g=Ww3gx3&utm_source=Youtube&utm_medium=video&utm_campaign=4-steps-feb-26 In the first five years after menopause, women lose up to 30% of their skin's collagen. Not gradually over decades, in five years. I sat down with Dr. Anthony Youn, America's Holistic Plastic Surgeon® and bestselling author of Younger for Life, to explore the powerful connection between your skin and your overall wellbeing. This conversation will completely change the way you think about aging, beauty, and the remarkable ability your body has to renew itself from the inside out. What we cover: - How Dr. Youn's philosophy of Autojuvenation® works to harness your body's natural regenerative abilities before turning to any clinical intervention. - Why the skin is the body's largest organ and functions as a 'magic mirror' that reflects your internal health, inflammation, and biological age. - What the five root causes of aging mean for midlife women. -  How women lose up to 30% of their skin's collagen thickness in just the first five years after menopause, and what you can do right now to fight back. - What a simple three-step morning skincare routine looks like, and why a quality vitamin C serum and sunscreen are the two non-negotiables for every woman over 40. - Why retinol remains the gold standard of anti-aging skincare, and which gentler plant-based alternatives are backed by clinical evidence for sensitive skin. - How exfoliation, microneedling, and energy-based treatments like IPL can signal your skin to regenerate collagen and reverse visible signs of sun damage. - What to look for when choosing a board-certified plastic surgeon and the critical questions that protect you from unqualified practitioners. About Dr. Anthony Youn: Known as America's Holistic Plastic Surgeon®, Anthony Youn, M.D. is a nationally-recognized, board- certified plastic surgeon. Recognized as a leader in his field, he is the author of the best-selling books "The Age Fix," "In Stitches," "Playing God," and "Younger For Life." Dr. Youn hosts the popular podcast The Doctor Youn Show. He is the most followed plastic surgeon on social media, with over 5.5 million subscribers on his YouTube Channel and 8 million followers on TikTok. He is also the founder of YOUN Beauty, a skin care and supplement line which focuses on natural and organic ingredients with scientifically proven anti-aging components. Connect with Dr. Anthony Youn: Instagram: www.instagram.com/tonyyounmd TikTok: www.tiktok.com/@doctoryoun 👉 YOUN Beauty Skin Care Use code VONDA to get $20 off your first order over $99: www.younbeauty.com 👉 Watch Dr. Youn's Podcast, "The Doctor Youn Show" www.youtube.com/@doctoryoun   Timestamps: 00:00 Intro 01:46 Why Dr. Youn shifted from 'cut-first' thinking to holistic plastic surgery 03:27 Autojuvenation® explained 05:02 Skin is the 'magic mirror' of internal health 08:03 Reframing vanity 10:56 What orthopedics and plastic surgery share 12:23 Collagen loss in menopause 14:07 How Hydrolyzed collagen actually enters your bloodstream 19:58 How sugar silently stiffens and ages your skin 24:49 The five causes of aging 29:30 The three-step morning skincare routine every woman over 40 needs 33:00 Vitamin C serums and what actually works 35:04 The anti-aging ingredient showdown 39:40 How to wake up sluggish skin 44:30 IPL and laser treatments for pigmentation 49:30 Regenerative treatments explained 54:20 How to choose a board-certified plastic surgeon safely 57:30 Free habit that changes everything 🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com/  

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity Today I want to talk with you about how women age, and why so many of us feel surprised by what happens to our bodies in midlife.   This is not an episode about chasing youth or fearing wrinkles. It is about understanding why women are not taught how longevity really works in our bodies, and why the years leading up to menopause matter far more than we were ever told. I have learned, through decades of caring for women as an orthopedic sports surgeon, that we are not simply smaller versions of men. Our biology has often been overlooked in longevity research, even though estrogen quietly influences nearly every system that determines how strong, mobile, and independent we remain as we age. I want you to know this. Aging is not something that happens to you. It is something you can shape. With the right information, a few consistent habits, and a deeper understanding of your own body, you can build strength and resilience that carry you forward for decades.   If you have ever felt like your body changed without warning, like the advice that once worked no longer does, or like aging has been framed as something to fear, this episode is for you. My hope is that this conversation leaves you feeling informed, supported, and empowered to age with strength, clarity, and confidence.   Timestamps (will update once final draft is available) 00:00 Introduction to Female Longevity 02:06 The Unique Aging Process of Women 03:19 Critical Data Points on Female Longevity 07:08 10 Essential Principles of Female Longevity 07:56 The Critical Decade: 35-45 09:27 The Role of Estrogen in Longevity 11:27 Body Composition Changes in Midlife 12:45 Mitochondria and Female Energy 13:49 Muscle Strength and Longevity 14:55 Cardiovascular Fitness and Lifespan 15:36 Brain Health and Estrogen 16:37 Inflammation and Aging 17:56 Modifying Biological Age 19:42 Conclusion: Designing an Unbreakable Future   🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/    📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/  Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/  TikTok: https://www.tiktok.com/@drvondawright  LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374  Website: http://www.drvondawright.com/   

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity   Your brain is not losing its mind by accident. It has been compounding every decision you've made for the last thirty years.   Louisa Nicola is one of my closest friends, and one of the most brilliant neurophysiologists working today, an elite triathlete and PhD researcher who has dedicated her life to understanding how the brain ages and, more importantly, how to stop it from declining. In this episode, Louisa and I pull back the curtain on everything you thought you knew about Alzheimer's disease, starting with the truth about amyloid, the protein we've been blaming for decades that is actually your brain's own defense system, and we build you a real, science-backed brain insurance policy: the specific exercise protocols, sleep requirements, hormonal factors, and daily habits that determine whether your mind stays sharp and fully yours well into your eighties and beyond.   What we cover: - How amyloid, long blamed as the villain of Alzheimer's disease, is actually your brain's own antimicrobial defense system. - Why Alzheimer's begins silently in your thirties and forties, not your eighties, compounding over decades. - What cognitive reserve means at the cellular level and how to build more of it starting now. - The specific exercise protocols, including resistance training and zone five, that protect your brain most. - How deep sleep triggers your brain's nightly cleaning system and why skipping it accelerates decline. - Why doing hard things, and learning new skills across your lifespan, physically grows your brain. About Louisa Nicola: Louisa Nicola is a neurophysiologist, Alzheimer's Disease scientist, and global authority on brain health. She is the founder of Neuro Athletics and the creator of BRAIN CODE, a science-driven program designed to help midlife women reduce their risk of Alzheimer's disease through measurable, preventative strategies. Trained at the University of Sydney Medical School, Louisa relocated to New York to work alongside leading neurosurgeons, contributing to clinical research in cranioplasty and post-operative neurological outcomes. Her work sits at the intersection of neurophysiology and exercise science, decoding how targeted lifestyle interventions rewire neural resilience and reshape the trajectory of cognitive aging. Through her research, keynote speaking, and top-ranked neuroscience podcast, Louisa challenges the fatalistic narrative around cognitive decline. Her mission is clear: Alzheimer's is a preventable disease, and women deserve the knowledge, tools, and measurable strategies to reduce their risk long before decline begins. Connect with Louisa Nicola: Instagram: https://www.instagram.com/louisanicola_/ LinkedIn: https://www.linkedin.com/in/louisanicola/ X (Twitter): https://x.com/louisanicola_ Website: https://www.neuroathletics.com.au/ Timestamps: 00:00 Intro 03:34 Brain as Hardware, Mind as Software 05:00 What Cognitive Reserve Looks Like Daily 07:00 What Amyloid Actually Is 09:20 How Viruses Silently Damage the Brain 11:27 Cognitive Reserve: What It Really Means 15:11 How Stress and Poor Sleep Destroy the Brain 17:00 Why Estrogen Is a Brain Hormone 21:11 Why Women Are Twice as Vulnerable to Dementia 23:00 Resistance Training and Zone 5 for Brain Health 27:07 Lactate: Alternative Brain Fuel in Perimenopause 31:45 How Your Brain Cleans Itself at Night 35:15 The Anterior Cingulate Cortex Explained 38:07 What Actually Builds Lasting Cognitive Reserve 43:46 Make Your Brain Your Best Friend   🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374  

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity What if the single most powerful window to shape your child's lifelong health isn't in the pediatrician's office, it's in the nine months before they're even born? In this episode, I sit down with Jessie Inchauspé, the French biochemist and NYT bestselling author known worldwide as the Glucose Goddess, to explore her groundbreaking new book Nine Months That Count Forever and why pregnancy nutrition is the most underestimated conversation in medicine today. What we cover: - How four pillars of pregnancy nutrition: choline, protein, omega-3s, and glucose control actively shape your baby's brain and metabolic health. - Why 90% of pregnant mothers lack enough choline, and how this egg yolk nutrient shapes your baby's brain cells and cognitive performance. - How glucose spikes pass to your baby in utero, programming greater vulnerability to obesity and diabetes for life. - Why building muscle before pregnancy protects both mother and baby from excessive blood sugar spikes. - What to do when first-trimester nausea strikes, and why one extra egg yolk a day can still make a difference.   About Jessie Inchauspe: Jessie Inchauspé is a French biochemist, founder, and international bestselling author. She has devoted her career to translating cutting-edge science into easy tips to help people improve their physical and mental health. Through her books Glucose Revolution and The Glucose Goddess Method, which have sold over 3 million copies in 43 languages, she has reshaped the global conversation around blood sugar. Nine Months That Count Forever, her latest, breaks down the complex topic of pregnancy nutrition. Jessie is the founder of the wildly popular social community @GlucoseGoddess, where she reaches over seven million people across platforms. She holds a BSc in mathematics from King's College, London, and an MSc in biochemistry from Georgetown University. Connect with Jessie Inchauspe: Website: https://www.glucosegoddess.com/pages/9-months-that-count-forever Instagram: https://www.instagram.com/glucosegoddess/ ▶️Jessie's new YouTube series on "What I (Glucose Goddess) Eat in a Day: Pregnancy Edition", a preview of what is to come in her new book. 📖 9 Months That Count Forever: How Your Pregnancy Diet Shapes Your Baby's Future Amazon: https://www.amazon.com/dp/1668219123 Simon & Schuster: https://www.simonandschuster.com/books/9-Months-That-Count-Forever/Jessie-Inchauspe/9781668219126 Timestamps 00:00 Intro 07:00 Jessie's Origin Story 10:30 How Blood Sugar and Mood Are Connected 13:00 Introducing Nine Months That Count Forever 16:00 The Four Pillars: Choline, Protein, Omega-3s and Glucose Management 18:30 Four Egg Yolks a Day and Why 90% of Moms Are Choline Deficient 22:00 More Choline in the Womb Means Faster Cognition and Higher IQ 24:00 Why Low Intake Sets a Blueprint for Low Muscle Mass for Life 26:00 Building Brain Cell Connections That Last a Lifetime 29:00 Glucose During Pregnancy: Why Your Spike Is Also Your Baby's Spike 33:00 The UK Sugar Ration Study 37:00 Practical Glucose Hacks for Pregnancy 39:00 How the Womb Sets Fat Cells, Muscle Mass and Disease Risk 44:00 Where to Start Today If You Are Overwhelmed 47:00 Why Preconception Nutrition Matters Just as Much as Pregnancy 🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374  

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity   You only build bone during deep sleep, and only if you get enough of a growth hormone spike to make it happen. As someone who has spent her career fighting osteoporosis, I had never connected those dots that clearly before. Morning light, deep sleep, and bone density are part of the same biological chain. That alone is worth the listen. This week, I am joined by Dr. John La Puma, the originator of culinary medicine. After reviewing over 2,200 studies for his new book, Indoor Epidemic, his conclusion is both sobering and actionable: we are spending 93% of our lives indoors, and our biology is paying for it in ways most of us cannot even perceive. Fatigue. Brain fog. Disrupted sleep. Accelerated aging. And we keep reaching for supplements and prescriptions when the answer is often just outside the door. What we cover: - Why 93% of our time indoors is a biological emergency quietly aging us faster from the inside out. - How 10 to 15 minutes of morning light resets your circadian clock and primes your body for deep, restorative sleep. - Why screen light within 30 minutes of bedtime drops melatonin by 20%, no matter what else you did right. - How deep sleep triggers the growth hormone spike your body needs to build bone, making it a frontline tool against osteoporosis. - Why green exercise feels 20% easier and drops cortisol by 21% when done in a place of your choice. - What digital obesity really means and why too many pixels burn out your brain the same way too much sugar burns out your metabolism. - How one hour of gardening a week can lower hemoglobin A1C by 0.5%, roughly equal to a starting dose of metformin. - What the Louisville Green Heart Study found, including a 22% drop in CRP, when greenery came to a community. - Why two to five intentional hours outdoors each week can give you up to five years of health span back.   About Dr. John La Puma: Dr. John La Puma is an academic clinician, trained chef, and organic farmer recognized as the originator of culinary medicine. He runs a certified organic educational farm in Santa Barbara and led the first CME course in the country teaching physicians to use nature as medicine. Indoor Epidemic is his distillation of 2,200 studies into a practical guide for reclaiming your biology. Connect with Dr. John La Puma: Website: https://www.drjohnlapuma.com/ Instagram: https://www.instagram.com/johnlapuma/   Timestamps 00:00 Intro 01:30 Culinary Medicine, Organic Farming and the Origin of a Field 03:30 The Indoor Epidemic: Why 93% Indoors Is a Biological Emergency 07:00 How 10 to 15 Minutes Resets Your Entire Biology 11:00 Screens, Melatonin and the 30-Minute Rule Before Bed 13:30 How Your Brain Cleans Itself During Deep Sleep 17:00 Why Over 50% of Your Genes Run on a Body Clock 20:00 20% Less Effort and a 19% Reduction in Mortality 24:00 Digital Obesity and What Ultra-Processed Time Is Doing to Your Brain 28:00 Indoor Air, Toxins, Carbon Dioxide and the Invisible Cognitive Drain 32:00 Chronic Inflammation, Telomere Shortening and Premature Aging 34:00 Greenery, CRP and Cardiovascular Health 38:30 Gardening, Hemoglobin A1C and the Metformin Comparison 41:00 Deep Sleep and Bone Building 44:30 The Biggest Barrier to Change and Why Knowledge Comes First 46:30 Two to Five Hours Outdoors a Week Can Add Five Years to Your Health Span   🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com/

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity Have you ever woken up feeling like a stranger in your own skin, wondering why the body that used to be so predictable now feels like a puzzle you can't quite solve? In this episode, I sit down with PhD nutrition scientist Dr. Emily Prpa to pull back the curtain on the "female gut" and explore why, for far too long, we've been given health advice designed for men while our own unique biology was left in the dark. What we cover: - The Gender Data Gap: Why nutritional advice is often derived from men and how it affects you. - Hormonal Control: How estrogen and progesterone dictate your digestion and heart health. - The Microbiome Shift: What happens to your gut during the transition to menopause. - The Power of Perspective: Viewing menopause as a "renewal" rather than an "abyss." - Early Warning Signs: Identifying fatigue and sleep issues long before hot flashes start. - Body Literacy: Learning to trust your physical instincts over social conditioning. - Midlife Nutrition: Using your microbiome to manage erratic hormonal shifts.   About the Dr. Emily Prpa: Dr. Emily Prpa is a PhD-prepared nutrition scientist and researcher dedicated to cutting through the noise of the wellness industry. She specializes in making complex science culturally relevant and practical, helping women understand the deep interplay between their gut health and their hormones.   Connect with Dr. Emily Prpa: Instagram: https://www.instagram.com/thenutritionreporter/ Website: https://www.dremilyprpa.com/ YouTube: https://www.youtube.com/@DrEmilyPrpa Timestamps (to be adjusted) 00:00 Dr. Emily Prpa on Decoding Science for Women 02:07 The Gender Gap: Why Your Nutrition Advice is Based on Men 03:55 Dealing with Sudden Bloating and Midlife Gut Changes 04:56 How Estrogen and Progesterone Control Your Digestion 06:37 Why Perimenopause Triggers New Digestive Symptoms 07:46 How Menopause Changes Your Gut's Biological Signature 09:40 Lessons from Japan's Empowering View of Menopause 10:36 Identifying Early Signs of Perimenopause You Might Miss 12:14 Overcoming the Medical Gaslighting of Women 13:14 Proactive Strategies to Prevent Midlife Bone Loss 15:12 How Your Gut Bacteria Recycles Estrogen 18:08 Fiber and Polyphenols for a Healthier Midlife Gut 32:15 Why Protein and Muscle Mass are Non-Negotiable Now 45:30 Small Lifestyle Shifts for Long-Term Vitality 🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com/  

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity   For years, we've focused on the external markers of health, but I've become increasingly obsessed with the internal landscape, specifically, how the food we eat communicates with our biology. We used to view nutrition as just calories in and calories out, but we now know it's a sophisticated signaling system that dictates our hormones, our mood, and even how we age. If you've felt like you're doing "everything right" but still feel exhausted or out of balance, the missing piece isn't your effort; it's likely the lack of foundational support for your internal "Amazon jungle", your gut microbiome.   In this episode, I sit down with the brilliant Dr. Amy Shah to discuss her new book, Hormone Havoc, and the simple yet profound framework she's developed to help women reclaim their vitality. We explore how moving away from restrictive diets and toward a science-backed "30-30-3" rule can stabilize your hormones, lower systemic inflammation by nearly 20%, and finally give your body the fuel it needs to thrive through perimenopause and beyond.   What we explore: - How the "30-30-3" framework simplifies nutrition for busy women by focusing on protein, fiber, and fermented foods. - Why eating 30 grams of protein in your first meal is a non-negotiable for mental focus and managing midlife cravings. - Why fermented foods like sauerkraut and yogurt act as a "walkie-talkie" to signal your immune system and lower inflammation. - How a daily goal of 30 grams of fiber can lower mortality by up to 10% by feeding your beneficial gut bacteria. - The critical role of the "estrobolome", gut bacteria that specifically regulate how estrogen is processed in your body. - Why modern medicine often overlooks practical nutrition training and why you must be your own advocate. - How simple "hacks" like adding chia seeds or raspberries can rapidly close your daily fiber gap. - What science says about the power of "postbiotics" found in traditional foods like sourdough bread.   About the Dr. Amy Shah: Dr. Amy Shah is a double board-certified medical doctor and nutrition expert who has taken the digital world by storm with her mission to help women feel less "effing tired". Through her clinical work and best-selling books, she bridges the gap between complex medical science and practical, everyday nutrition that fits into the busy lives of modern women.   Connect with Dr. Amy Shah: Instagram: https://www.instagram.com/dramyshah Website: https://amymdwellness.com/   Timestamps (placeholder)   00:00 Intro 05:40 The "criminal" lack of nutrition education in traditional medical training. 07:15 Breaking down the 30-33 Framework: Protein, Fiber, and Fermented Foods. 10:42 The Internal Amazon Jungle: How gut bacteria communicate with your brain. 14:15 Secrets of Longevity: Why the world's oldest woman ate yogurt three times a day. 18:40 Understanding the Estrobolome: The gut-hormone connection you need to know. 21:05 Fiber Hacks: How raspberries and chia seeds can lower your mortality risk. 24:30 The Protein Breakfast Rule: Why 30 grams at your first meal changes your entire day. 35:15 Practical fermented food swaps for those who don't like kimchi. 46:30 Why your best years and your best work are still ahead of you.   🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com/

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity   I've spent years focusing on your external mobility, but I've become obsessed with the world living inside you. We used to think of the gut as just a digestion tube; now we know it's a thriving ecosystem and a metabolic pharmacy that dictates your weight, mood, and longevity. If you're doing "everything right" but still struggling with energy, the issue isn't your willpower, it's your microbiome.   In this episode, I sit down with researcher Dr. Karen Corbin to decode the gut's "black box." We're moving beyond basic digestion to explore how fiber triggers the same satiety hormones as modern weight-loss injections. Stop viewing food as mere calories and start seeing it as fuel for your internal garden. It's time to stop fighting your biology and start partnering with your bacteria to design a resilient future from the inside out. What we cover: - How your gut bacteria produce Butyrate, a "magic" compound that heals the gut and lowers inflammation. - The science of how fiber and resistant starch signal your brain to feel full and satisfied. - Why ultra-processed foods are "too easy" for our bodies to digest, leading to metabolic disaster. - Why "industrial milling" is the hidden enemy of metabolic health, turning even "healthy" grains into rapid glucose spikes by making them too easy to digest. - Why your choices at dinner determine your blood sugar response to breakfast the next morning, proving that your microbiome works on a 12-to-24-hour cycle. - Understanding that because every person's "internal garden" is unique, the same "healthy" food can cause a sugar spike in one person while keeping another perfectly stable. - Exploring the deep connection between the health of your microbiome and the energy-producing engines in your cells that drive your vitality.   About Dr Karen Corbin: Dr. Karen Corbin is a PhD researcher and keynote speaker at the forefront of precision nutrition with Advent Health. She has dedicated her career to decoding the "black box" of the microbiome, revealing how our internal pharmacy dictates metabolic health and longevity.   Connect with Dr Karen Corbin: LinkedIn: linkedin.com/in/karen-corbin-phd-rd-75229111 Website: https://www.geeksthatspeak.com/ Timestamps 00:00 Intro 01:46 Meet Your Microbes: The Colon as a Metabolism 'Show' 05:58 How the Microbiome 'Talks' to You: SCFAs, Bloodstream & the Vagus Nerve 09:28 Feed the Good Guys: Fiber, Mucus Barrier & 'Leaky Gut' Explained 14:23 Aging, Exercise, Antibiotics & Hormones: What Changes in Perimenopause 18:27 Prebiotics vs Probiotics vs Synbiotics: Yogurt, Capsules & What Actually Helps 22:24 Can You Test Your Microbiome? The Limits of Diagnostics & Expensive Probiotics 27:29 Diet Can Remodel Your Gut: The 4 Research-Backed Levers 32:12 Does Food Order Matter? + CGM Lessons on Carbs, Protein, and Spikes 35:48 Practical Breakfast Upgrades: Oats, Flax, Nuts, and Easy Wins 37:00 Calories Aren't One-Size-Fits-All: Microbes, Absorption, and Weight Differences   🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com/  

Get Dr. Vonda's latest insights on strength, bone health, longevity, and aging with power delivered straight to your inbox. Join her free health & longevity newsletter here: https://www.drvondawright.com/resources/aging-longevity   Through decades of caring for women as an orthopedic sports surgeon, I've seen how many health challenges go unspoken. Body odor, vaginal health, and the shame and silence around them are not small issues. They affect confidence, relationships, and how women move through the world.   In this conversation, Shannon and I explore how a simple clinical observation became a breakthrough in understanding how odor works on the body. We discuss why women were taught to mask symptoms instead of understanding their source and how deeply stigma has shaped the way they experience their own bodies.   Shannon shares her journey from clinical practice to building products based on physiology rather than marketing myths. We also talk about the power of listening without judgment and giving women the language, knowledge, and permission to understand their bodies without embarrassment.   What we cover: - How Shannon's clinical practice revealed a hidden but widespread problem for women - Why odor is a bacterial issue, not a hygiene failure - The difference between masking symptoms and addressing root causes - How shame has shaped women's health messaging for decades - Why the vulva, skin folds, and external body deserve the same scientific attention - What it takes to challenge medical dogma as a woman physician - The leap from medicine to entrepreneurship and the resistance along the way - Building products that respect women's intelligence and lived experience - Why listening to patients changes everything - How confidence, dignity, and health are deeply connected About Shannon Klingman: Dr Shannon Klingman is an OB-GYN, innovator, and founder of Lume. She brings a rare blend of clinical insight, scientific rigor, and fearless honesty to women's health. Her work has helped millions of women better understand their bodies, free from shame, misinformation, or outdated advice.   Connect with Shannon Klingman: Website: https://lumedeodorant.com/ Instagram: https://www.instagram.com/shannon_klingman_md TikTok: https://www.tiktok.com/@shannon.klingman.md   Timestamps   00:00 Intro 02:27 The Birth of Lume: A Revolutionary Idea 05:42 Developing the Product 08:12 Facing Skepticism and Rejection 10:53 Breaking Through with Marketing 17:40 Scaling and Team Building 25:11 Balancing Family and Business 28:56 The Reality of Entrepreneurial Success 31:12 Personal Health and Lifestyle Changes 35:22 Breast Cancer Diagnosis and Recovery 45:06 Future Aspirations and Reflections   🦴 Unbreakable Bone Health Dr. Vonda's Unbreakable Bone Health formula supports bone density and strength using patented ingredients backed by 30 years of clinical research. 🛒 Shop now → https://shop.drvondawright.com/   📖 Unbreakable: A Woman's Guide to Aging with Power Dr. Vonda Wright's newest book, Unbreakable, is a bold guide for women ready to redefine what aging looks and feels like. Blending cutting‑edge science with real‑world strategies, it helps you build strength, resilience, and momentum through every decade of life. Discover how to turn aging into your greatest advantage and live with power, purpose, and vitality. 👉 Learn more or get your copy: https://theunbreakablebook.com   About Dr. Vonda Wright: I'm Vonda Wright, an orthopedic sports surgeon and women's healthy‑aging expert. For 20 years I've helped athletes and everyday women protect their joints, build muscle, and extend their health span. Here you'll get science-backed strategies to age with power, so you can keep doing what you love for decades to come.   Connect with Dr. Vonda Wright: Instagram: https://www.instagram.com/drvondawright/ Read Dr. Vonda Wright's Substack: https://drvondawright.substack.com/ TikTok: https://www.tiktok.com/@drvondawright LinkedIn: https://www.linkedin.com/in/vonda-wright-md-ms-2803374 Website: http://www.drvondawright.com/