Episode 90 - The scientific approach to urticaria

Professor Marcus Maurer and Professor Martin Metz reflect on the European Academy of Allergy and Clinical Immunology (EAACI) congress 2024, including novel treatments on the horizon, key takeaways and expectations for future meetings.  Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Remibrutinib demonstrates favourable safety profile and sustained efficacy in chronic spontaneous urticaria over 52 weeks; and European Medicines Agency approved indications for omalizumab biosimilar. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Professor Marcus Maurer welcomes Dr Jörg Scheffel to discuss urticaria, including techniques used to interrogate mast cells and examine interstitial fluid, and a technique used to identify autoimmune-mediated forms of urticaria. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Chronic urticaria and the pathogenic role of mast cells; A novel approach for studying mast cell-driven disorders: Mast cells derived from induced pluripotent stem cells; Autoreactive IgE: Pathogenic role and therapeutic target in autoimmune diseases. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Professor Elias Toubi joins Professor Marcus Maurer to discuss remission in urticaria, including its definition and possible risk factors for long disease duration. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Clinical and laboratory parameters in predicting chronic urticaria duration: A prospective study of 139 patients. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Associate Professor Elena Borzova joins Professor Marcus Maurer to discuss exercise as a trigger for urticaria in some athletes, including the paradoxical protective effect of exercise in people with urticaria. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Exercise-induced urticaria: A rare case report; and Physical activity and mental health among patients with atopic dermatitis or chronic spontaneous urticaria: A cross-sectional study. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Professor Marcus Maurer welcomes Dr Carolina Vera Ayala and Associate Professor Jonny Peter to discuss participation in clinical trials for urticaria, including patient concerns around placebo treatment. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: What is clinical research and why is it done?  Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Professor Marcus Maurer welcomes Professor Philip Li to discuss the management of urticaria in Hong Kong, including access to effective treatments and socioeconomic and cultural factors. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Hong Kong–Macau severe hives and angioedema referral pathway, Disparities in chronic spontaneous urticaria: Eligibility for drug reimbursement associated with clinical outcomes, Chronic spontaneous urticaria in Hong Kong: Clinical characteristics, real-world practice and implications for COVID-19 vaccination Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

Dr Jason Hawkes joins Professor Marcus Maurer to discuss dermatologists’ lack of urticaria knowledge, including tips on encouraging the US dermatology community to use resources such as the CRUSE app. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Additional resources for this episode: Key messages: Urticaria guidelines; Urticaria: A comprehensive review and Hives: Diagnosis and treatment. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

“This is a global problem that requires global solutions, but I think they do come from what we learn in our settings.” Professor Marcus Maurer welcomes Dr Clive Grattan to discuss the differences in the treatment and management of urticaria across the UK and Germany, including guideline recommendations and new treatments on the horizon. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Utilise the following external links and access additional resources relating to the topics discussed in this episode: British Association of Dermatologists guidelines for the management of people with chronic urticaria 2021 and The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

“I think CARE will grow and grow.” Dr Thomas Buttgereit joins Professor Marcus Maurer to discuss the recently launched Chronic Angioedema Registry (CARE), including benefits for patients, current capabilities and how to get involved. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Utilise the following external links and access additional resources relating to the topics discussed in this episode: Chronic Angioedema Registry. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.

“There’s still so much we need to learn.” Dr João Marcelino joins Professor Marcus Maurer to discuss autoimmune chronic spontaneous urticaria, including indicative test results and hopes for the future. Do you have suggestions for future episodes? Please provide feedback and offer your suggestions for future topics and expert selection here. Utilise the following external links and access additional resources relating to the topics discussed in this episode: What basophil testing tells us about CSU patients – results of the CORSA study, Autologous serum skin test reactions in chronic spontaneous urticaria differ from heterologous cell reactions and Omalizumab in chronic spontaneous and inducible urticaria: A 9-year retrospective study in Portugal. Access additional resources by signing up to Medthority and to be notified for future ‘All Things Urticaria’ podcast episodes! For more information about the UCARE/ACARE network and its activities, please visit: UCARE Website, UCARE LevelUp Program, ACARE Website, UCARE 4U Website, UDAY Website, CRUSE Control App and CURE Registry.