Kyle Shanahan previews 49ers' season opener, Christian McCaffrey listed as questionable

Mac Jones might have rebooted his career in the 49ers' 26-21 win over the New Orleans Saints on Sunday at Caesars Superdome. Under the tutelage of San Francisco coach Kyle Shanahan, Jones looked the part of an NFL starting quarterback with a 279-yard, three-touchdown performance as an injured Brock Purdy watched from the sideline. Matt Maiocco and Jennifer Lee Chan break down how the 49ers' offense utilized Jones' arm early and often, and also identify which rookies stepped up amid injuries on both offense and defense ahead of next weekend's home opener against the Arizona Cardinals.--(1:00) 49ers fans traveled well in Week 2 in New Orleans(3:00) Dissecting Mac Jones' performance as starting QB(4:00) Brock Purdy injury update(13:00) Biggest surprise from Jones' start vs. Saints(21:00) Eddy Piñeiro made positive first impression despite early hiccup(22:30) Breaking down standout rookie performances

Matt Maiocco speaks with 49ers coach Kyle Shanahan about their Week 2 matchup vs. the New Orleans Saints and Mac Jones' San Francisco debut on Sunday in place of injured starting quarterback Brock Purdy. Also Greg Papa joins Matt to break down key matchups in this weekend's game.--(4:48) Kyle Shanahan on decision to release kicker Jake Moody(6:45) Shanahan details what Mac Jones will bring in his 49ers debut(8:21) What can 49ers expect facing former assistant head coach Brandon Staley?(11:39) Shanahan shares why George Kittle is irreplaceable for 49ers(15:42) How will Kendrick Bourne fit into San Francisco’s offense?(25:10) Greg Papa shares latest update on his battle with cancer(30:53) Papa felt Brock Purdy got hit too many times during Seahawks game(35:53) Papa believes 49ers’ offense compromised after injuries to Kittle, Jauan Jennings

The 49ers brought an end to the Jake Moody saga Tuesday by waiving the beleaguered kicker, opting to bring in veteran Eddy Piñeiro as his replacement. Matt Maiocco and Jennifer Lee Chan break down how San Francisco and Moody arrived to this point and how the 49ers will fare at this position moving forward. The duo also discusses Brock Purdy's pair of injuries and George Kittle's placement on injured reserve, as well as Kendrick Bourne's return. Then, Matt sits down with Jake Tonges' former high school coach to discuss the backup tight end's emergence from Los Gatos, Calif., to the pros.--(1:00) Recapping the 49ers' busy couple of days after Week 1 win(2:00) Breaking down fan reaction to Moody being waived(7:30) How will the 49ers replace Kittle's receiving reps?(13:00) Analyzing Purdy's toe, shoulder injuries(19:00) Moody's downfall leads to veteran replacement in Piñeiro(36:00) How Tonges' football journey led him to game-winning TD(38:00) Why Tonges has real opportunity to make impact in Kittle's absence

The 49ers rallied late for a 17-13 comeback victory over the Seattle Seahawks on Sunday at Lumen Field. While San Francisco's defense produced several key performances, a surprising face on offense made the play of the game when third-string tight end Jake Tonges stepped up in George Kittle's injury absence. Matt Maiocco and Jennifer Lee Chan break down the roller-coaster ride that was the 49ers' Week 1 win, from outstanding defense and gritty offense to their erratic special-teams play.--(1:00) 49ers hold on for late win in wild finish(3:00) Tonges delivers with game-winning TD(7:00) Jauan Jennings, George Kittle will have MRIs on injuries(12:00) CMC a main reason 49ers won(17:45) Jennifer details postgame vibe in 49ers' locker room(21:00) 49ers' special teams roller-coaster continues(23:00) How long can Jake Moody remain 49ers kicker?(26:00) Special teams as a whole must be fixed(29:00) Biggest player personnel takeaways from Week 1

Matt Maiocco speaks with San Francisco 49ers coach Kyle Shanahan about their Week 1 matchup vs. the Seattle Seahawks and why he's optimistic about Christian McCaffrey's health despite the star running back being listed as questionable for Sunday's game. Greg Papa also joins to provide an encouraging update on his cancer battle.

As 49ers quarterback Brock Purdy leads San Francisco into its 2025 NFL season opener, gone are the days of Mr. Irrelevant. Equipped with a lucrative new contract and a young family in tow, Purdy sits down "49ers Talk" host Matt Maiocco to discuss how he adjusts to all of these changes, including a complete roster overhaul this offseason. Brock and Matt touch upon what motivates the 25-year-old and he can take his game and the 49ers organization to the next level, one snap at a time.-(1:00) Ramping up for the 49ers' first game of the season(3:00) Jauan Jennings to play against Seattle(17:00) How Purdy balances being QB and a new dad(20:00) Does Purdy’s contract change anything?(23:00) Purdy's leadership through service and work ethic(27:00) Where can Purdy take his game to another level?(30:00) Roster updates heading into Week 1

With Sunday’s season opener against the Seattle Seahawks looming, Matt Maiocco and Jennifer Lee Chan discuss the latest updates on Jauan Jennings’ calf injury and contract extension negotiations, and debate if Jennings will suit up for the 49ers in Week 1. Also, Matt and Jennifer break down San Francisco's wide-receiver depth and detail what Brian Robinson Jr. brings to the team's run game.--(1:30) Analyzing the 49ers’ new 'Rivalries' series alternate jerseys(10:30) Will Jauan Jennings suit up for the season opener on Sunday?(16:16) GM John Lynch confirmed Jennings requested a trade(18:00) What would a Jennings contract extension look like?(26:17) 49ers entering 2025 NFL season with a full squad(30:30) Breaking down 49ers’ wide-receiver depth(34:25) San Francisco interested in reuniting with former 49ers receiver Kendrick Bourne(38:34) Matt details what Brian Robinson Jr. brings to 49ers’ running game

With Tuesday's roster cutdown deadline officially passed, there were a few surprises for the 49ers at key positions. Matt Maiocco and Jennifer Lee Chan discuss their biggest takeaways from San Francisco's initial 53-man roster, from the ailing wide-receiver corps and heavily invested defensive line, to a special-teams group facing mounting pressure. Also, we'll hear from newly acquired running back Brian Robinson Jr., who is poised to make the 49ers' backfield the most potent in the league.--(1:00) Surprises from 49ers' initial 53-man roster(3:00) Addressing questions about receiving corps(4:00) Jennings, 49ers remain quiet about contract(15:00) Breaking down each position group(21:00) Shocking inclusions, exclusions from O-line(29:00) Jake Moody remains on roster; it's his job to lose

After the 49ers' 30-23 win over the Los Angeles Chargers in Saturday's preseason finale, their attention now turns to the 53-man roster deadline on Tuesday. Matt Maiocco and Jennifer Lee Chan discuss each position group's depth and how Kyle Shanahan, John Lynch and Co. will whittle the roster down. New additions Skyy Moore and Brian Robinson Jr. join the team as roster locks, but which players will be cut?  Also, Matt sits down with NBC Sports Washington's JP Finlay to discuss what the Robinson trade brings to the 49ers' locker room.--(1:00) Reviewing 49ers' preseason-finale win vs. Chargers(4:00) What Skyy Moore, Brian Robinson Jr. trades bring to 49ers(9:00) Assessing 49ers' running-back depth(13:00) Exploring where Jauan Jennings situation stands(21:00) Is Jake Moody's situation untenable?

With former 49ers coach Jim Harbaugh and the Los Angeles Chargers visiting Levi's Stadium for Saturday's preseason finale, San Francisco's final roster decisions are becoming more clear. Matt Maiocco and Jennifer Lee Chan discuss what will play into the 49ers' roster choices, including injury updates, player suspensions and position-group competitions. Also, Matt and Jennifer review how the entire 2025 NFL Draft class has fared throughout training camp, and discuss Kyle Shanahan's update on veteran wide receiver Demarcus Robinson's suspension following his violation of the NFL's personal conduct policy last season.--(1:00) Demarcus Robinson suspension update(2:00) Roster decisions shaping amid numerous injuries(10:00) Health top priority as backups set to play in preseason finale(20:00) Jim Harbaugh returns to Levi's Stadium as known program-fixer(25:00) 49ers rookie progress