The Six Five with Patrick Moorhead and Daniel Newman podcast

EP 289: Infrastructure, Capital, and the Reality of AI Scale

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Patrick Moorhead and Daniel Newman explore how infrastructure constraints, capital dynamics, software consumption shifts, and regulatory friction are increasingly determining who can scale intelligent systems, featuring an exclusive "Off The Record" conversation with Martin Casado, GM of the Infrastructure fund at a16z (Andreessen Horowitz).

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https://x.com/PatrickMoorhead

https://x.com/danielnewmanUV

 

Follow the guest: 

https://x.com/martin_casado

 

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THE DECODE

Enterprise AI moves from pilots to production
https://siliconangle.com/2025/12/17/enterprise-ai-hpe-tackles-execution-problem-hpeaimomentum/ SiliconANGLE

AI memory and infrastructure supply pressures
https://www.reuters.com/world/china/ai-frenzy-is-driving-new-global-supply-chain-crisis-2025-12-03/ Reuters

Data center stocks and power bottlenecks in focus
https://ts2.tech/en/data-center-stocks-week-ahead-dec-22-26-2025-ai-mega-deals-power-bottlenecks-and-export-control-risk-in-focus/ TechStock²

AI capex boom meets power-grid bottlenecks
https://ts2.tech/en/data-center-stocks-ai-capex-boom-meets-power-grid-bottlenecks-todays-news-and-2026-outlook-dec-20-2025/ TechStock²

Tech executives share AI infrastructure insights
https://siliconangle.com/2025/12/19/top-tech-executives-share-ai-insights-thecube/ SiliconANGLE

AMD positions for massive compute growth in AI era
https://www.techradar.com/pro/amd-ceo-welcomes-us-to-the-yottascale-era-lisa-su-says-ai-will-need-yottaflops-of-compute-power-soon TechRadar

 

THE FLIP

China's power availability could redefine AI compute leadership
https://www.businessinsider.com/elon-musk-china-ai-compute-exceed-electricity-power-2026-1 Business Insider

Data center geography and sustainability challenges
https://theweek.com/tech/data-center-locations-climate-water-energy-ai The Week

 

BULLS & BEARS

AI stock momentum, Nvidia, Micron, and data-center arms race
https://ts2.tech/en/ai-stocks-today-dec-26-2025-nvidias-groq-deal-chinas-hard-tech-push-and-the-global-data-center-arms-race/ TechStock²

Cloud computing stocks outlook with AI demand
https://ts2.tech/en/cloud-computing-stocks-outlook-dec-20-2025-ai-data-center-boom-powers-microsoft-amazon-alphabet-and-tests-oracle TechStock²

AI infrastructure rebound amid memory demand and costs
https://ts2.tech/en/data-center-stocks-today-micron-ignites-an-ai-infrastructure-rebound-as-oracle-funding-questions-and-power-grid-costs-loom-dec-18-2025/ TechStock²

Cisco networking and AI infrastructure tailwinds
https://ts2.tech/en/cisco-systems-csco-news-on-dec-25-2025-ai-networking-tailwinds-fy2026-forecasts-and-a-critical-email-security-zero-day/

 

For a deeper dive into each topic, please click on the links above. Be sure to subscribe to The Six Five Pod so you never miss an episode.

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