
E85: Randolph Nesse - Evolutionary Explanations for Biology and Psychiatry
My guest today is Randolph Nesse, a founder of evolutionary medicine whose work with George Williams inspired many to expand explanations of disease from descriptions of why and how mechanisms fail in some individuals, to evolutionary explanations for traits that leave all individuals in a species vulnerable to a disease. Their six categories of possible explanations have become canonical: the limits of natural selection, mismatch
with environments, arms races with pathogens, trade-offs, gene transmission at the cost of robustness, and defensive responses. After 40 years as a Professor of Psychiatry and of Psychology at the University of Michigan, Nesse moved to Arizona State University to start a new Center for Evolution and Medicine, and the International Society for Evolution Medicine and Public Health. His focus is now returning to his original mission of trying to provide a solid scientific foundation for psychiatry through evolution.
We discussed evolution, cultural group selection, Mormonism, life and death, mental problems, natural selection, emotions, being vulnerable to failure, aging, biology, asking - how does it work and how did it get that way?, being vulnerable to disease, ancestral environments, anthropology, depression, anxiety, panic attacks, the smoke detector principle, love, evolutionary treatment, social traps, and the acronym SOCIAL - social resources, occupation, children, income, abilities, and love.
Episode Details:
Guest Name: Randolph Nesse
Website: http://www.RandolphNesse.com
Book: https://www.randolphnesse.com/good-reasons-book-info
X / Twitter: https://x.com/randynesse
LinkedIn: https://www.linkedin.com/in/randolph-nesse-97647b38/
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