MitoSure or Mito-Not-Sure: Should You Trust the MitoSure Score?

Send us a textAre Day-7 embryos doomed to fail — or are they just late bloomers? In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols explains why embryos that don’t reach blastocyst until Day 7 have lower implantation and live birth rates compared to Day 5 or 6. Using a marathon analogy, he breaks down how timing reflects embryo quality, metabolism, and chromosomal health. You’ll also hear the surprising history of Day-7 embryos — from being discarded in the early 2000s to becoming a viable option thanks to advances in culture systems and vitrification. Most importantly, Dr. Amols puts these odds into perspective: while Day-7 embryos aren’t front runners, many healthy babies have still been born from them.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textIn this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols takes a deep dive into the ZyMōt microfluidic sperm chip — a device designed to mimic nature’s way of selecting the healthiest sperm.We explore:Why sperm DNA fragmentation matters for fertilization, embryo quality, and miscarriage risk.How the ZyMōt chip works compared to traditional methods like swim-up and density gradient centrifugation.What the science really shows — from lab data to clinical trials — including studies where the chip nearly doubled live birth rates in male-factor infertility, and others where it made little difference in unselected IVF populations.Which patients benefit the most: men with high DNA fragmentation, couples with male-factor infertility, and those with failed fertilization or poor embryos in past cycles.Practical considerations — cost, limitations, and why some clinics use it for everyone while others use it selectively.Is it a true game changer, or just another lab gadget? Tune in to find out.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textToday’s episode comes straight from a listener question: What’s the deal with MitoSure? Is this mitochondria-based score the secret weapon in embryo selection — or just another lab test with a fancy name and fuzzy usefulness?Join Dr. Mark Amols as he takes you on a wild science ride from embryo scoring to evolutionary biology, bacterial roommates, and the ancient origin of mitochondria. You'll learn what MitoSure actually measures, why the same embryo could score a “2” in one lab and an “18” in another, and why most fertility specialists still treat it as a tiebreaker — not a dealbreaker.Whether you're mid-IVF or mitochondria-curious, this episode is packed with helpful info, analogies, and (of course) tacos.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textIn this week’s episode of Taco Bout Fertility Tuesday, Dr. Mark Amols takes you on a guided tour of your baby’s very first pictures—the first trimester ultrasound. From the tiny gestational sac to the yolk sac (your baby’s first lunchbox), to the fetal pole and that reassuring flicker of a heartbeat, Dr. Amols explains what each step really means and when you should expect to see it. You’ll also learn:Why we stop checking hCG once we see the sacWhat it means if a yolk sac is missing or measures unusually small or largeHow to understand the fetal pole and when to expect a heartbeatGrowth benchmarks from “grain of rice” to “strawberry”Why being 3–7 days behind may (or may not) be concerningHow and why the placenta forms, and when we can actually see itWhat nuchal translucency is, what causes it, and what it does—and doesn’t—meanOne ultrasound is just a snapshot, but together they create the story of the first trimester. If you’ve just found out you’re pregnant—or you’re supporting someone who has—this episode will help you decode what’s on the screen and know what to expect in those exciting early weeks.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textYou finally got the positive test after IVF or IUI — now what? In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols walks you through the first steps after a positive pregnancy test, from confirming with beta hCG bloodwork to your first ultrasound. Learn why rising numbers matter more than the absolute hCG value, why it’s crucial not to stop progesterone or estrogen too early, and what milestones to expect in the first 6–10 weeks.Dr. Amols also shares common myths, tips for healthy habits, and insight into the emotional rollercoaster of “graduating” from your fertility clinic to your OB. Whether you’ve just seen those two pink lines or are preparing for this moment, this episode offers practical guidance, reassurance, and hope for your next chapter.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textUnderstanding the different types of Diminished Ovarian Reserve and what they mean for your fertility journeyBeing told you have Diminished Ovarian Reserve (DOR) can feel overwhelming — but the truth is, it’s not the same diagnosis for everyone. In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols breaks down the “automobile” analogy to explain why DOR is a broad category that can mean very different things depending on the cause.You’ll learn:The four common “models” of DOR and how each affects fertilityWhy age, AMH, AFC, and FSH tell different parts of the storyHow your specific type of DOR shapes your treatment planReal patient stories that prove DOR doesn’t always mean poor outcomesThe essential questions to ask your doctor if you’re diagnosed with DORIf you or someone you know has been labeled with DOR, this episode will help you replace fear with clarity — and empower you to make the right next step for your situation.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textEver had an amazing IVF cycle followed by one that made you question everything? You’re not alone—and no, your ovaries didn’t suddenly revolt. In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols breaks down the statistical concept of regression to the mean—why extreme fertility outcomes often return to average over time.From IVF cycles to PGT results, hormone levels to semen analysis, you’ll learn why bouncing numbers aren’t always bad—and why your “worst cycle ever” might just be math doing its thing. Packed with analogies, real patient stories, and just enough nerdy data to make you feel smarter than your doctor’s EMR, this episode is for anyone riding the emotional rollercoaster of fertility treatment.🎯 The takeaway? Don’t panic over the highs or the lows. Zoom out. It’s the trend that tells the truth.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textThere’s a lot to worry about in IVF: Will you get enough eggs? Will your embryos be normal? Will the transfer work?But for Dr. Mark Amols, there’s one part that truly keeps him up at night—fertilization.In this deeply personal episode of Taco Bout Fertility Tuesday, Dr. Amols shares why fertilization is the most unpredictable and emotionally gut-wrenching step in the entire IVF process. You’ll get a crash course in reproductive biology—meiosis, pronuclei, 0PNs, 2PNs, and more—and learn what really happens the night sperm meets egg.He explains:Why even perfect sperm and eggs can fail to fertilizeThe terrifying uncertainty of ICSI and why it doesn’t guarantee successHow fertilization failure happens—and why it feels like a blindsideWhat embryologists look for when checking for normal fertilizationThe brutal truth about age, egg quality, and cellular deathWhether you’re preparing for IVF, recovering from a failed cycle, or just want to understand the science behind the scariest moment in the lab, this episode delivers the insight—and honesty—you won’t hear anywhere else.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textWhere did the semen go? In this week’s episode of Taco Bout Fertility Tuesday, Dr. Mark Amols unpacks one of the lesser-discussed causes of male infertility—low semen volume and retrograde ejaculation.From the science of what makes up semen (spoiler: sperm is only about 3% of it!) to the coordinated dance between the sympathetic and parasympathetic nervous systems, you’ll learn how the body decides when to open and close the right channels during urination and ejaculation.We break down:What qualifies as “low volume”How retrograde ejaculation happens—and how to spot itConditions like diabetes, surgeries, and medications that can cause itDiagnostic tools including post-ejaculatory urinalysisTreatment options including Sudafed, sperm retrieval, and IVF/ICSIOther causes of low volume like ejaculatory duct obstruction and congenital absence of the vas deferensWhether you're a patient, partner, or just curious about how sperm can get lost in transit, this episode is full of insight, clarity, and of course—compassion and tacos.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Send us a textThink infertility is just a female issue? Think again. In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols serves up some tough love (and solid science) about male fertility. From hormonal red flags and testicular trauma to lifestyle choices and personal history, this episode breaks down when men should consider that they might be the reason pregnancy isn’t happening.Whether you’ve been “lucky” to avoid pregnancy in every relationship or just assumed things were working fine because, well, you feel fine — it’s time to check the scoreboard.No blame. Just facts, awareness, and a gentle reminder: sometimes the strongest move a man can make… is handing over a cup.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform. Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com. Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected]. Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.