
S 873: A1C Explained: When This Popular Marker Helps, and When It Misleads
A1C is one of the most commonly used markers for assessing metabolic health, but it’s also one of the most misunderstood. In this episode, I revisit the “Overrated or Underrated” framework to break down what A1C actually measures, where it can be useful, and why it often fails to tell the full story. We explore the many conditions, supplements, medications, and physiological states that can falsely elevate or suppress A1C, leading to flawed conclusions about insulin sensitivity. Topics discussed:
- What A1C measures
- Overrated versus underrated markers
- False A1C elevations
- False A1C reductions
- Anemia and A1C
- Protein intake effects
- Medications and A1C
- Endurance training considerations
- Ethnicity and lab interpretation
- Better insulin sensitivity markers
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“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
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