The Rise of Deepfake Medical Imaging

Hosted by Dr. Ashwin Singh Parihar, this episode features Dr. Mickael Tordjman and Dr. Bachir Taouli discussing their landmark Radiology study on AI‑generated deepfake medical images that are realistic enough to fool trained radiologists. Together, they examine what this new level of image realism means for diagnostic accuracy, clinical trust, and the future of safeguards in medical imaging.   The Rise of Deepfake Medical Imaging: Radiologists' Diagnostic Accuracy in Detecting ChatGPT-generated Radiographs. Tordjman and Yuce et al. Radiology 2026; 318(3):e252094.   The Democratization of Deceit: Seeing Is No Longer Believing. Bhayana and Krishna. Radiology 2026; 318(3):e260466. 

Dr. Celina Nahyun Jo talks with Dr. Mahla Radmard about how NEXUS and the Canadian C‑Spine Rule shape cervical spine imaging decisions in trauma patients. Together they explore new research that questions long‑standing imaging practices and highlights opportunities to improve value safety and accuracy in patient care. Evaluating National Emergency X-Radiography Utilization Study and Canadian C-Spine Rule Criteria and Their Clinical Impact on Cervical Spine Imaging: Best Practice. Asadollahi and Arjmand et al. Radiology 2026; 318(1):e243834.

Dr. Refky Nicola speaks with Dr. Atul Shinagare about his team's research showing that incidental adnexal lesions on single‑phase CT are often difficult for radiologists to classify consistently, with only certain classic lesions yielding strong agreement. Their conversation underscores the limitations of CT compared with ultrasound or MRI and reinforces that most incidental adnexal findings are benign, though many still require additional imaging for clarification. Incidental Adnexal Lesions: CT Diagnosis and Interreader Agreement. Guo et al. Radiology 2026; 318(2):e243477.   

Dr. Ashwin Parihar speaking with Drs. Sungmin Woo and Alberto Vargas about why standardized PSMA PET scoring systems—such as PSMA‑RADS and PROMISE—are becoming essential for consistent interpretation, communication, and treatment planning in prostate cancer. They explore the evidence behind these frameworks, current barriers to adoption, and how future harmonization efforts like the SPARC Initiative may shape the evolution of PSMA PET reporting. Navigating the Scoring Systems and Interpretation Frameworksof Prostate-specific Membrane Antigen PET. Woo and Masci et al. Radiology 2025; 317(3):e250701.  

Dr. Lauren Kim speaks with Adarsh Mallepally and Dr. Cory Trankle about their large-scale retrospective study of nearly 4 million patients examining the risk of nephrogenic systemic fibrosis after gadolinium-based contrast administration in those with advanced renal dysfunction. They discuss how modern group 2 and macrocyclic agents were associated with an exceedingly low incidence of NSF, offering important reassurance for evidence-based contrast use and evolving clinical practice. Nephrogenic Systemic Fibrosis in Patients with Advanced RenalDysfunction Following Gadolinium-based Contrast Agents. Mallepally et al. Radiology 2025; 317(3):e251794.   

Dr. Linda Chu speaks with Dr. Kavitha Chinnaiyan and Dr. Jonathon Leipsic about why 2026 marks an inflection point for coronary CT, from AI-enabled plaque quantification to FFR-CT and evolving guideline support for CT-first evaluation of suspected coronary artery disease. They explore how advanced imaging tools are reshaping risk assessment, personalizing prevention and revascularization decisions, and strengthening collaboration between radiology and cardiology while highlighting the need for validation, standardization, and equitable access.

Dr. Reni Butler speaks with Dr. Anne Marie McCarthy and Dr. Christine Edmonds about their study examining Black–White racial differences in background parenchymal enhancement (BPE) on contrast-enhanced breast MRI. They discuss the finding that black women had higher odds of high BPE independent of breast density, explore potential biologic and environmental drivers, and consider how quantitative BPE assessment could improve breast cancer risk stratification and screening equity. Black-White Racial Differences in Background Parenchymal Enhancement at Breast MRI. Mahmoud et al. Radiology 2026; 318(1):e251041.

Hosted by Dr. Lauren Kim, this episode explores the most downloaded Radiology article of 2025 with guests Dr. Carolyn Wang, Dr. Allison Ramsey, and Dr. David Lang, focusing on updated consensus guidance for managing hypersensitivity reactions to iodinated contrast media. The discussion highlights major changes in clinical practice, including more selective use of corticosteroid premedication and switching contrast agents when feasible to reduce the risk of recurrent reactions and standardize patient care. Management and Prevention of Hypersensitivity Reactions to Radiocontrast Media: A Consensus Statement from the American College of Radiology and the American Academy of Allergy, Asthma & Immunology. Wang et al. Radiology 2025; 315(2):e240100.

Dr Linda Chu and co-hosts Drs Refky Nicola, Lauren Kim, and Reni Butler look back on the Top 10 most downloaded Radiology articles of 2025, highlighting the studies and consensus statements that resonated most with readers worldwide. From breast imaging and AI to MR safety, contrast reactions, and beyond, this episode explores why these papers mattered and how they are shaping clinical practice. Top Publications in Radiology, 2025. Fowler and Goh. Radiology 2025; 317(3):e253887.

Radiology podcast host Dr Linda Chu and co-hosts Drs Celina Jo, Sid Dogra, Lauren Kim, and Refky Nicola look back at the most cited Radiology articles of 2025, highlighting the research that most influenced clinical practice and scientific discourse. The episode explores key advances across imaging modalities, AI, and emerging technologies, offering context on why these studies mattered and what they signal for the future of radiology. Top Publications in Radiology, 2025. Fowler and Goh. Radiology 2025; 317(3):e253887.