Psychedelics and the Brain's Hemispheres - Adam Levin

Dr. Adam Levin, a psychiatrist and researcher, based at Ohio State University's Center for Psychedelic Drug Research and Education (CPDRE). Adam works at the intersection of psychedelics, psychiatry and neuroscience. In this conversation, we discuss Adam's recent paper, which proposes a new theory about how psychedelics work, focusing on the intriguing role of brain lateralisation in psychedelic experiences and therapeutic outcomes.

My guests today are Bruce Wampold and Pim Cuijpers, two of the leading experts in the research of the effectiveness of psychotherapy. Bruce is Emeritus Professor of Counseling Psychology at the University of Wisconsin–Madison and author of the seminal book, The Great Psychotherapy Debate: The Evidence for What Makes Psychotherapy Work. Pim is Professor Emeritus of Clinical Psychology at the Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam and is also director of the WHO Collaborating Centre for Research and Dissemination of Psychological Interventions. In this conversation, we discuss the evidence for psychotherapy as a whole, the evidence for how the effectiveness of different psychotherapies compare, how to study the drivers of change in psychotherapy (such as the “therapeutic alliance”) and discuss what the current evidence suggests as fruitful avenues for the future of psychotherapeutic research and practice.

My guest today is Dr Chris Letheby, a philosopher working on issues related psychedelic drugs who is currently a lecturer in philosophy at the University of Western Australia and a postdoctoral researcher at the University of Adelaide. Chris is also the author of the book Philosophy of Psychedelics, which was published in 2021 by Oxford University Press. In this conversation we touch on the account given in Chris' book of the therapeutic benefits of psychedelics, and then go deep into Chris' account of the phenomenology of psychedelics. This conversation was a lot of fun, and I hope you enjoy it as much as I did.

My guest today is Ros Knight is a Clinical and Counselling Psychologist with over 25 years experience and the President of the Australian Psychological Society (the largest professional organisation of psychologists in Australia) from 2017-20 was the Clinical Director at Macquarie University for nearly 14 years. This conversation is something of a guide for people who may be considering getting professional psychological support for the first time. We discuss when to see a psychologist, what to look for in a psychologist, how to know if you and your therapist are a good fit and how to get the most out of therapy.

  My guest today is Professor Ralph Piedmont, Professor of Pastoral Counselling at Loyola University in Maryland and a past president of the APA's Society for the Psychology of Religion and Spirituality. In this conversation, we discuss spirituality as a clinically-relevant personality trait, and how one can go about integrating spirituality into clinical practice. Ralph is also co-author (with Teresa Wilkins) of the recently published book, Understanding the Psychological Soul of Spirituality. **20% Discount Available to MindStew listeners - with the code BSE20**  

My guest today is Professor Ralph Piedmont, Professor of Pastoral Counselling at Loyola University in Maryland and a past president of the APA's Society for the Psychology of Religion and Spirituality. In this conversation, we discuss the nature of spirituality as a personality trait (arguably the sixth personality trait!) that cuts across cultures and religions, it's relevance for clinical practice and wellbeing and the nature of the FFM domain of openness to experience and its maladaptive expressions. Ralph is also co-author (with Teresa Wilkins) of the recently published book, Understanding the Psychological Soul of Spirituality. **20% Discount Available to MindStew listeners - enter the code BSE20 at checkout**

My guest today is Professor Jonathan Smallwood (@the_mindwanders), Professor of Psychology at Queens University in Canada. Jonny researches the neuroscience of the phenomenon of spontaneous, internally generated thought, as exemplified by mind-wandering and day-dreaming. To me, this is an interesting topic because it is; a) something that we do all the time, b) relevant to high-prevalence mental health conditions (such as rumination and worry in depression and anxiety), and c) is quite different from other most neuroscience areas that tend to be studied through specific tasks. In this conversation, we discuss the function of mind-wandering, whether it makes us unhappy, its relationship to the default-mode network, the position of the default-mode network in the brain's processing hierarchy and the challenges and opportunities of studying spontaneous thought.

In this episode I speak with Jay Sanguinetti, Research Assistant Professor and Director of the NICE Lab (Non-Invasive Cognitive Enhancement Lab) at the University of New Mexico, and Science Director of the SEMA Lab (Sonification Enhanced Mindful Awareness) Associate Director of the Center for Consciousness Studies at the University of Arizona.  Dr. Sanguinetti investigates the use of noninvasive brain stimulation to enhance cognition and well-being. We discuss Jay’s work investigating whether focused ultrasound can be used to augment meditation practice in the development of mindfulness. I found this conversation fascinating as it highlights how modern brain technologies could enhance wellbeing and also because the impact could be significant; while mindfulness is an effective intervention for pain, addiction, and mood disorders, many people don’t persist with mindfulness training long enough to experience the full benefits. 

In this episode I speak with Norm Farb, Assistant Professor in the Department of Psychology at the University of Toronto, and Principal Investigator of the Regulatory and Affective Dynamics Lab.  Dr. Farb studies the neuroscience of the self and emotion with a focus on how cognitive biases shape the emotional reactions that influence well-being, and how these biases and emotional reactions are affected by cognitive training practices such as mindfulness meditation. He has led several influential studies on the mechanisms of mindfulness training and depression vulnerability, highlighting that resilience against depression stems more from the growth of mindfulness-related skills, such as interoceptive awareness, than the eradication of residual depressive symptoms. 

Today we speak again with Professor Josef Parnas, Professor of Psychiatry at the University of Copenhagen and a co-founder and Senior Researcher at the Danish National Research Foundation: Center for Subjectivity Research. In our first conversation we discussed the implications of taking the phenomenology of schizophrenia seriously, and covered topics such as importance of clinical experience, and adequacy of current systems to classify psychopathology. But after the interview I realised that we didn’t really discuss the phenomenology of schizophrenia itself and felt that I had missed an opportunity to learn from someone with so much experience. So in this episode, I ask of a lot of basic questions to better understand what schizophrenia is and what life is like for those with it.