Most replayed moment: Why muscle gain matters more than weight loss | Vonda Wright

How can you enjoy sugar without gaining weight, fuelling cravings or crashing later in the day? The answer, surprisingly, is not to cut it out. In today’s episode, Professor Tim Spector and Professor Sarah Berry discuss which forms of sugar affect your blood sugar levels most, and what small changes you can make today to reduce the impact. They also explore how sharp blood sugar spikes and dips may affect hunger, energy, inflammation and long-term health. By the end of the episode, you’ll know how to spot hidden sugars, how to avoid the afternoon slump and energy crashes, and, most importantly, how to enjoy cake with less impact on your blood sugar. Sugar is not the enemy. But could a few small changes help you enjoy sweet foods without the cycle of cravings, hunger and energy crashes? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 03:28 If fruit is full of sugar, why is it good for us? 08:30 What really happens after you drink a sugary drink? 12:46 Why sugar leaves you hungry a few hours later 16:15 The blood sugar dip that makes you eat 320 extra calories 19:19 The surprising link between sugar and inflammation 22:00 Can blood sugar affect your brain health? 25:25 What the science really says about sugar and cancer 29:25 We've been blaming sugar for the wrong things 31:45 The 2 types of sugar most people confuse 32:35 The hidden sugars lurking in everyday foods 35:32 Why energy drinks may be worse than you think 38:51 Why orange juice may not be as healthy as you think 40:10 Why fruit and fruit juice are not the same thing 43:53 Why some smoothies behave like sugary drinks 45:03 Should you quit sugar completely? 46:46 Are sweeteners helping or keeping you hooked? 49:55 Is honey actually healthier than sugar? 51:40 3 everyday foods with surprisingly high sugar 52:27 How to enjoy cake without the blood sugar crash 55:01 The 10-minute habit that lowers your glucose response 57:15 Why energy drinks may be making your slump worse 58:32 The biggest sugar traps to watch out for 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode Dietary Sugar Intake Associated with a Higher Risk of Dementia, Journal of Alzheimer's Disease (2024) Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Mortality, AHA (2019) A Twin Study of Acne in Women, Journal of Investigative Dermatology (2002) Bananas and weight loss: What does the science say? Food Order and Impact on Glucose and Insulin Levels, Diabetes Care (2015) Here are 4 ways to help manage your blood sugar Whole Fruits Versus 100% Fruit Juice, BNF (2025) Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

Today we’re talking about muscle mass. For many people, losing weight is the ultimate health goal. However, focusing solely on lowering the number on the scale often means overlooking something crucial: muscle mass. We know that increasing muscle makes us stronger, but it also plays a surprising role in metabolism and helps keep unwanted fat at bay. Dr. Vonda Wright joins me to explain why improving your body composition may be the smarter goal for lifelong health. 🌱 Try our science-backed and tasty wholefood supplement Daily30 Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

What really helps you live a long, healthy life? Can healthy ageing be as simple as a few everyday habits? In this episode, Dr. Ezekiel Emanuel, world-leading oncologist, bioethicist and World Health Organization adviser, shares six rules from his book Eat Your Ice Cream that may help lower your risk of dementia, heart disease, cancer and early death.  Ezekiel explores the science of healthy ageing, longevity and disease prevention, and explains why many wellness trends distract us from what matters most. By the end of the episode, you’ll have six practical habits that have the biggest impact on living well for longer. From building stronger relationships and staying mentally active to improving your diet, exercise and sleep, Ezekiel offers a simple framework designed to support health over decades, not weeks. If you want to live a longer, healthier life, are you focusing on the habits that matter most?  🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Why more exercise may not help you live longer03:49 The book that made a leading doctor furious08:11 Why wellness culture thrives when life feels out of control10:52 What the wellness industry gets wrong about longevity13:05 Are peptides and supplements dangerous?16:28 How much alcohol is safe to drink?18:52 How ultra-processed food affects your brain and body23:49 Is vaping safer than smoking?25:35 Which vitamins and supplements are actually worth taking?28:09 Rule one: The risks that are never worth taking30:12 Is climbing Everest more dangerous than you think?31:27 The number one rule for a longer, healthier life33:35 How loneliness increases your risk of early death35:51 What loneliness does to your immune system and heart37:03 How many close friends do you need for better health?39:20 Is working from home harming your mental health?40:08 How to rebuild your social life when you feel isolated40:52 Four vaccines linked to a lower risk of dementia44:21 Is retirement bad for your brain?45:32 Four simple food rules for better gut health47:56 The three types of exercise you need as you age50:17 How many hours of sleep do you really need?52:24 Is sleep less important than social connection?54:02 Why sleeping pills may not improve your sleep56:13 The one habit that combines all six longevity rules 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode Eat Your Ice Cream: Six Simple Rules for a Long and Healthy Life by Dr. Ezekiel Emanuel Multivitamins and cognitive health, Annals of Medicine and Surgery (2026) The (un-)Social Brain, Physiological Research (2025) Association between social activity frequency and overall survival, BMJ (2023) The Health and Retirement Study Harvard Study of Adult Development Mistakenly seeking solitude, Journal of Experimental Psychology (2014) Home alone: Remote work, isolation, and mental health, Science (2026) Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

Today, we’re talking about Omega-3. Omega-3 fats have been celebrated, scrutinised, and debated for decades. While some research points to remarkable heart health benefits, other studies suggest they can actually raise the risk of cardiovascular disease. So where does the science stand today? Should we supplement, rely on food, or rethink our approach to omega-3 completely? Dr. Bill Harris and Professor Sarah Berry join me to cut through the confusion, explain omega-3’s role in the body, and share an evidence based approach to this fascinating fatty acid. 🌱 Try our science-backed and tasty wholefood supplement Daily30 Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

We all want to eat healthier. The Paleo diet promises exactly that: eat like our ancestors, avoid modern foods, and improve your health. But does it really support your gut, heart and long-term health, or is the story more complicated? In this episode, Dr James Cole, a world-leading expert on prehistoric diets, joins Dr Federica Amati to explore what Paleo gets right and why some of the claims may be dangerously wrong. James explains what ancient evidence tells us about human diets, why the modern-day Paleo diet may go too far in its restrictions, and what that might mean for your heart disease risk and gut health. By the end of the episode, you’ll have ideas on what principles to keep from the Paleo diet, and what rules to avoid. Could trying to eat as our ancestors did force you to cut foods your body actually needs? Before you give up grains, beans or dairy, it may be worth asking what ancient humans really ate. 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 04:39 What does Paleolithic actually mean? 09:14 How scientists know what ancient humans ate 10:01 What ancient teeth reveal about diet 11:25 Why there was no single Paleo diet 13:16 The myth that ancient humans just ate meat 15:38 Why humans evolved to eat many foods 17:14 Why the human gut got smaller 22:13 How fire changed the human diet 24:02 Were ancient humans cooking plants? 25:51 What modern eating has lost 27:45 Did Paleolithic humans practise cannibalism? 30:37 Should we copy everything our ancestors ate? 32:56 What is the modern Paleo diet? 34:32 What the Paleo diet gets right 37:00 Did our ancestors eat meat every day? 38:18 Why Paleo cuts grains, dairy and beans 39:30 Are lectins in beans really dangerous? 41:27 Why modern Paleo may be based on shaky science 42:20 Is the Paleo diet healthy long term? 44:45 What a healthier Paleo diet would look like 46:17 The processed meat and cancer risk trap 48:37 Is grass-fed beef really better? 50:10 Should you fast like your ancestors? 52:10 How to cut ultra-processed foods without Paleo 56:20 What to eat instead of strict Paleo 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode The Paleolithic diet and chronic disease risk, Critical Reviews in Food Science and Nutrition (2026) Long-term Paleolithic diet is associated with increased serum TMAO concentrations, European Journal of Clinical Nutrition Evidence for mitigation of dental caries by Neanderthals, PLOS One (2026) Evidence for the diets of Neanderthals and early modern humans, PNAS (2009) Long-term effects of a Palaeolithic-type diet, European Journal of Clinical Nutrition (2014) The Big IF Study: What did we find? The Expensive-Tissue Hypothesis, International Journal of Molecular Sciences (2018) Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

Today we’re talking about breast cancer. Here at ZOE, we know that health is deeply personal - and breast cancer risk is no different. Your likelihood of developing breast cancer is shaped by factors such as genetics, body composition, and lifestyle.  Understanding your individual risk is crucial because it helps determine when and how you should be screened - and in some cases, it could save your life. Today, I’m joined by Dr. Thais Aliabadi to explain why breast cancer screening shouldn’t follow a one-size-fits-all approach, and how her own experience with cancer has influenced the way she thinks about prevention. 🌱 Try our science-backed and tasty wholefood supplement Daily30 Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

Can food improve brain health, memory and mood?  In this episode, Prof Felice Jacka and Prof Tim Spector explore how diet, the gut microbiome and fermented foods may affect your mood, brain function and dementia risk. Drawing on clinical trials and research involving more than 10 million people, they explain why what you eat could have a much bigger impact on your brain than most people realise, and what the latest science suggests you can do about it. Felice, who helped create the field of nutritional psychiatry, explains how food influences the brain through the gut microbiome and inflammation. She and Tim explore why some foods change brain function, which support brain health, what the evidence says about ultra-processed foods, and why diet is becoming an increasingly important part of research on brain and mental health. Learn which foods to eat more often, which foods to reduce, and simple, affordable ways to build meals that support your gut, mood and long-term brain health. From whole grains and legumes to fermented foods and everyday supermarket and grocery store choices, by the end of the episode, you’ll have realistic advice that’s easy to put into practice today. If the food you eat today helps shape your brain tomorrow, what small change could make the biggest difference over the next year? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 03:10 Why beans may boost mood more than cake 07:35 Can diet reduce your risk of depression? 10:10 Can changing your diet put depression into remission? 12:45 How does the gut microbiome affect the brain? 16:04 Can gut microbes transfer depression symptoms? 17:55 What gut bacteria are missing in mental illness? 20:16 Is food the most powerful tool for brain health? 22:11 The yogurt study that surprised neuroscientists 25:35 Can fermented foods help grow the hippocampus? 28:18 Why fermented foods may improve mood and energy 30:16 The gut-brain connection explained simply 31:13 How diet during pregnancy affects brain development 37:52 Are depression, anxiety and dementia connected? 39:27 What are ultra-processed foods really doing to your brain? 39:55 The major study linking ultra-processed foods to disease 42:31 Are some ultra-processed foods healthier than others? 43:44 Real food vs meal replacements: what happens to your microbiome? 48:29 The ingredient Felice Jacka tries to avoid 50:16 Do supplements improve brain health? 52:23 The best foods for brain health and mental health 53:37 How to eat for brain health on a budget 55:40 The simplest brain health advice you’ll hear today 58:40 The complete brain health and gut health checklist 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode The 'SMILES' trial, BMC Medicine (2017) Mood Disorders: The Gut Bacteriome and Beyond, Biological Psychiatry (2024) ZOE study: Fermented food improves mood, energy, and hunger Effects of a probiotic fermented dairy product on the brain, Gut microbiota (2025) Associations between diet quality and depressed mood in adolescents, ANZJP (2010) Ultra-processed food exposure and adverse health outcomes, BMJ (2024) Global Burden of Disease, The Lancet (2026) Folic acid, ageing, depression, and dementia, BMJ (2002) Transplantation of gut microbiota derived from patients with schizophrenia induces schizophrenia-like behaviors, Nature (2024) Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

Today we’re talking about blood pressure. Most of us know that high blood pressure is bad — but surprisingly few of us understand what it actually means, how widely it affects the body, or how to keep it under control. The good news is that monitoring blood pressure is easier than ever, putting you in a strong position to spot problems early and take meaningful action. Professor Tim Spector joins me to explain what blood pressure is, why it matters so much, and share some top salt-based tips that can have a powerful impact on long-term health. 🌱 Try our science-backed and tasty wholefood supplement Daily 30+ Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Free resources from ZOE Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide

How quickly can you improve your gut health? Can diet help lower your risk of dementia? And what should you know about food labels and healthy weight loss? In this special live Q&A, Prof Tim Spector, Prof Sarah Berry and Dr Federica Amati answer your biggest nutrition questions and share practical, evidence-based advice you can use today. Drawing on decades of research and data from hundreds of thousands of people, they explain how diet can influence the gut microbiome, brain health, hunger, energy levels and long-term health. They discuss dementia risk, healthy snacking, intermittent fasting, ultra-processed foods, plant diversity, breakfast, food labels and the latest science on weight loss. You’ll learn how quickly the gut microbiome may respond to dietary change, why some foods keep you fuller for longer, how to build a healthier breakfast, and simple ways to make better food choices. The team also explain why small dietary changes can have lasting benefits. If your daily food choices influence your gut health, brain health and future wellbeing, which change is worth making first? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 01:56 The first ever live ZOE podcast 09:14 How long does it really take to improve your gut microbiome? 12:56 Can you feel healthier before your gut microbiome changes? 14:15 Which foods should you always buy organic? 16:33 Are oats actually healthy? 18:36 The overnight oats trick that may improve blood sugar 19:28 Resistant starch: the hidden nutrient most people miss 21:32 Always hungry at 3pm? Sarah’s evidence-backed fix 27:17 The food industry trick that makes you eat more 29:44 Why ultra-processed foods leave you hungry 30:50 Does chewing more food really help you lose weight? 33:23 What does gut health have to do with depression and anxiety? 37:45 Is your gut controlling your brain? 39:34 Are fermented foods the most underrated brain-health food? 41:46 Starting Ozempic or Wegovy? Do this first 42:40 What do GLP-1 drugs do to your gut microbiome? 45:20 Tim Spector’s plan to fix Britain’s health crisis 47:55 Why governments still aren’t acting on ultra-processed foods 50:50 Have US food guidelines changed—and is the UK falling behind? 53:08 Is intermittent fasting safe for women? 56:15 What’s the healthiest breakfast to break a fast? 58:20 The science breakthroughs that could change nutrition forever 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode Daily Sampling Reveals Personalized Diet-Microbiome Associations in Humans, Cell Host & Microbe (2019) ZOE’s PREDICT studies: What we’ve learned ZOE snacking study: What should you do? The Big IF Study: What did we find? Diet and Dementia, Neurology (2024) Daily30: Does it work? Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

Today, we’re talking about supplements. We’ve all seen them; the multivitamins, the fortified foods, the neatly packaged powders promising improved energy, immunity and longevity.  Supplements boast bold claims, however, it’s hard to know if they’re genuinely helpful or just well-marketed. Professor Tim Spector and Professor Sarah Berry join me to unpack why supplements exist, what the science really says about their benefits and risks, and how to decide if supplements deserve a place in your daily routine. 🌱 Try our science-backed and tasty wholefood supplement Daily 30+ Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Free resources from ZOE Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know hereListen to the full episode here