
Why do your legs sometimes give up during an ultramarathon when your breathing feels comfortable and your aerobic fitness suggests you could keep going?
In this episode of the Trail Running Briefing, we explore ultra durability, the ability to maintain muscular strength, running efficiency and movement quality as fatigue accumulates over hours of running.
Drawing on recent scientific research, we examine why muscle damage and neuromuscular fatigue can become major performance limiters in long mountainous ultras, particularly during repeated climbs and descents.
We also explore the difference between building a powerful aerobic engine and developing the muscular resilience needed to support it.
Most importantly, this episode provides practical, evidence-based guidance on how to improve durability through progressive strength training, downhill conditioning, race-specific long runs, intelligent pacing, fuelling and recovery.
Ultra performance isn't just about how fast or efficiently you run when fresh. It's about how much of that performance you can preserve when fatigue arrives.
Train your engine. Strengthen your chassis. Build the durability to reach the finish line.
Key references:
1. Tiller & Millet (2025). Decoding Ultramarathon: Muscle Damage as the Main Impediment to Performance. Sports Medicine.
2. Muñoz de la Cruz et al. (2026). Decoding Neuromuscular Fatigue in Trail Running: A Systematic Review Across Distances and Sex Differences. International Journal of Sports Physiology and Performance.
3. Zanini et al. (2025). Strength Training Improves Running Economy Durability and Fatigued High-Intensity Performance in Well-Trained Male Runners. Medicine & Science in Sports & Exercise.
4. Giandolini et al. (2016). Effect of the Fatigue Induced by a 110-km Ultramarathon on Tibial Impact Acceleration and Lower Leg Kinematics.
5. Vernillo et al. (2015). Energy Cost and Kinematics of Level, Uphill and Downhill Running: Fatigue-Induced Changes After a Mountain Ultramarathon. Journal of Sports Sciences.
6. Bontemps et al. (2025). Muscle Soreness but Not Neuromuscular Fatigue Responses Following Downhill Running Differ According to the Number of Exercise Bouts. European Journal of Sport Science.
7. Llanos-Lagos et al. (2024). The Effect of Strength Training Methods on Middle-Distance and Long-Distance Runners' Athletic Performance: A Systematic Review with Meta-analysis. Sports Medicine.
8. Hunter et al. (2025). Durability as an Index of Endurance Exercise Performance: Methodological Considerations. Experimental Physiology.
9. Garbisu-Hualde & Santos-Concejero (2020). What Are the Limiting Factors During an Ultra-Marathon? A Systematic Review of the Scientific Literature.
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