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Trevor Manz went from measuring plant apertures by hand in a wet lab to building the notebook that lets coding agents take the wheel. The creator of anywidget and founding engineer at marimo (marimo.io/pair) popped into The Test Set to spill on reactive notebooks, why marimo pair threw out every MCP tool but one, and what agents really want out of a data environment. This conversation also features a jacket bouncer, a hidden Python API, and Michael's slow-motion war with the word "marimo."
What's inside:
- Cell order doesn't matter in a reactive Python notebook
- Wet-lab pipettes and Harvard's visualization group, via Raspberry Pi
- The problem with building beautiful tools nobody actually uses
- The reason marimo pair deleted every agent tool but one
- Code mode: the hidden API humans aren't supposed to touch
- What happens when you ship the API your LLM hallucinated
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