Human Trials for Anti-Aging Drugs!

What if we stopped treating aging as “natural” and started treating it like a disease?In this episode of the Molecule Podcast, Ella McCarthy-Page (Sci Comms Lead at Molecule)and Alana Tara Singh (Behavioural Strategist) unpack a seismic shift in how governments are approaching longevity science. The German National Academy of Sciences has officially defined aging as a disease target, opening the door for clinical trials, new drug development, and the first regulatory frameworks focused on reversing age-related decline.They’re joined by Michael Torres (co-founder, R10 Bio & VITA RNA), who shares why he’s launching a human clinical trial targeting post-chemo aging in Abu Dhabi, a country now fast-tracking longevity drugs under radical new trial standards.You’ll learn:* Why aging wasn’t treatable (until now)* What Germany’s new policy really means* How Rapamycin exposed the flaws in current regulation* Why Abu Dhabi is leading the longevity race* The role of DeSci in decentralized drug development* How R10 Bio used Molecule’s IP-NFT model to raise funds* The real story behind Michael’s anti-aging therapyWelcome to the future of proactive medicine! Let’s reimagine aging before it redefines us.Timestamps:00:00 – Intro with Ella & Alana00:34 – Germany now targets aging as a disease01:30 – Why regulators blocked anti-aging drugs02:40 – Rapamycin and the loophole problem04:00 – Why off-label drugs are risky05:20 – Germany’s surprise leadership in longevity06:00 – Abu Dhabi’s radical trial reforms09:15 – Raves, cappuccinos & Gen Z health trends10:00 – Can we prevent cancer by targeting aging?10:50 – What is R10 Bio’s therapy actually doing?12:00 – The DeSci fundraising journey with Molecule13:10 – From mutation suppression to clinical readiness14:00 – Why Abu Dhabi was chosen for trials14:40 – Michael Torres on aging post-chemo16:00 – Defining a huge market with aging-related outcomes17:00 – Why rare disease trials don’t scale18:00 – How Abu Dhabi is implementing FDA “guidance”

What if your healthspan was backed by a token? What if trading fees funded science? And what if longevity wasn’t just about “not dying”, but about living better for the ones you love?In this episode of the Molecule Podcast, we dive deep with Jillian and Benji, the team behind Pump Science, a protocol that combines crypto markets with open scientific experimentation to find real longevity compounds. But this episode isn’t just technical. It’s deeply human.From bonding curves and tokenomics to holding your child longer, this is what decentralized science looks like when purpose meets protocol.We cover:* The emotional “why” behind longevity research* How crypto markets fund real scientific experiments* Testing pipeline: from worms to flies to mice to humans* The design of the Pump Science game, and how it rewards curiosity* How you can submit your own idea for a longevity compound* What’s next for Pump ScienceThis is more than a podcast, it’s a thesis on how the future of health could be fun, fair, and radically open.—Timestamps:0:00 – Intro: Do you want to live for tomorrow?1:45 – A mother’s promise: holding her son longer5:35 – Longevity as emotional responsibility8:12 – Why crypto is the only viable engine10:10 – Pump Science protocol explained from first principles14:42 – Launching a compound via bonding curve17:55 – Who are the players? Drug devs & gem hunters24:18 – What happens when a token “migrates”29:34 – How token trading fees fund real experiments32:20 – The buyback & burn mechanic37:02 – The new standard for supplement + data39:15 – Why not wait for human data? Worms, flies & predictive efficiency48:04 – Pump Science vs other longevity efforts (Brian Johnson, etc.)50:25 – How much has actually been studied in longevity?55:00 – Why this system must exist, or nothing will change57:02 – Making science fun again: designing a game people want to play1:00:00 – Fly racing & the next experimental features1:02:30 – Launching more tokens, testing more ideas1:04:05 – How you can submit your own compound1:05:40 – Final vision: best products, open data, real change🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to: ______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

What if your immune cells came with a smart upgrade?In this episode of the DeSci Podcast, we speak with Dr. Henry Erdlei, medical doctor, cancer researcher, and founder of GoCart, a new cell therapy platform building safer, modular CAR-T therapies through decentralized science.Henry breaks down:* How CAR-T cell therapies work* The real-world risks of immune overactivation* Why cancer is hard to distinguish from healthy tissue* The problem with existing logic gates in cell therapies* His own innovation: an external AND-gate adapter system* Why DeSci and IP-NFTs are the right path for early-stage therapeutics🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]:00 – Intro: What is CAR-T therapy?2:00 – Henry’s background & journey into cancer research4:20 – What T-cells do and why they fail in cancer7:30 – CAR-T vs chemotherapy: cost, complexity, and potential11:00 – Which cancers are eligible for CAR-T treatment?13:10 – Risks: cytokine storms, immune cascades, suicide switches17:30 – Emily Whitehead: the first CAR-T success story20:30 – Current limitations of approved CAR-Ts (CD19, BCMA)23:00 – Introducing GoCart and their “AND gate” design26:00 – Why tumor targeting needs precision logic29:00 – Modular CAR-Ts and the future of personalized medicine32:00 – Why GoCart is building in public with Molecule34:30 – Can DeSci unlock truly customizable cell therapies?37:00 – From research to startup: bridging the valley of death40:00 – How to follow GoCart and get involved______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

What if you were told that your body is secretly responding to Wi-Fi signals you can't even feel?In episode 49 of the Molecule Podcast we meet Dr. Geoff Anders (Founder, Leverage) and Dr. Clarice D. Aiello (Quantum Engineer), to explore the cutting-edge field where quantum physics meets biology, revealing how the smallest particles in the universe might be controlling the largest processes in life itself. Whether you're a scientist, technologist, or simply curious about the quantum world around us, this deep dive into quantum biology will change how you think about life, technology, and the future of medicine.        • Quantum biology explained in simple terms• Weak magnetic field effects on cellular processes• The radical pair mechanism and quantum sensing in nature• Space exploration and magnetic field implications• DeSci (Decentralized Science) and crypto funding for research• The future of quantum-controlled medicine• Open science and radical transparency in researchTake a leap into the never ending world of science and imagination with this podcast.Timestamps:00:00:02 - Introduction to Quantum Biology00:02:31 - Quantum Physics in Everyday Life00:04:34 - Understanding the Micro to Macro Connection00:08:11 - Weak Magnetic Fields and Cellular Response00:10:31 - Space Exploration and Magnetic Fields00:14:10 - Mars Colonization Challenges00:15:10 - Future Applications00:16:57 - Personal Backgrounds00:18:36 - From Quantum Sensors to Biology00:20:16 - The DeSci Connection00:27:07 - Real-World Applications Vision00:31:09 - Multiple Flavors of Quantum Biology00:35:45 - Music and Plant Growth00:43:19 - The Consciousness Question00:54:06 - Radical Open Science00:55:15 - How to Get Involved00:56:39 - Final Thoughts🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to: ______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

What if science wasn’t locked in labs or universities?In episode 47 of the Molecule Podcast, we meet Juan Keymer, Assistant Professor, Shenzhen X-Institute who enlightens us on the existing academic pipeline and how it can be made more flexible with the advancement in AI, DeSci (Decentralized Science), Blockchain Innovation, Open Credentials and more.• Reimagining the future of Science with DeSci.• This is a deep, thoughtful, and radically hopeful conversation about the future of learning, research, and planetary collaboration.• Indulge in a world of Science with Juan Keymer and Ella McCarthy-Page (SciComms Lead at Molecule) away from textbooks and traditional academic systems.In this fascinating episode, we dive deep into reimagining the infrastructure of science away from elite institutions and toward decentralized, gamified systems that anyone can engage in.Timestamps00:00:00 – Introduction: A New Vision for Science00:03:15 – The Problem with Academia & Closed Scientific Systems00:10:47 – Open Degrees & Scope for Open Credentials 00:15:20 – The New Scientific Interface00:20:34 – Biotic Games: How Living Systems Become Game Mechanics00:28:45 – Open Hardware and Decentralized Labs00:35:06 – Rewiring Academia: Parallel Programming & Self-Credentialing00:37:00 – Metaverse & Blockchain-Powered Ecosystems00:41:00 – Fun First, Research Second00:43:00 – Final Reflections: The Power of Play in Scientific Discovery🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

Over $2.2 billion in NIH research grants are frozen. Labs are going dark. What happens now?In Episode 46 of the Molecule Podcast, we speak with Aaron Weaver, Chief Commercial Officer at Molecule, about the ongoing NIH funding crisis, its global impact, and how decentralized science (DeSci) is becoming a critical alternative.Aaron brings a unique vantage point from the intersection of venture capital, biotech, and public science funding. This episode unpacks:• The real story behind the NIH funding freeze• Why the budget cuts on indirect costs are threatening university research• What happens when academia loses funding momentum• How DeSci offers new models for sustainability and collaboration• How to get involved — even if you’re not a researcherIf you care about the future of scientific discovery, this episode is essential.Timestamps- 0:00 – Intro: The NIH funding crisis1:30 – What’s actually frozen? Why $2.2B is stalled2:50 – Meet Aaron Weaver: CCO of Molecule & DeSci advocate5:00 – Why indirect costs are at the center of the issue9:00 – How operational freezes threaten lab survival11:30 – The fragility of foundational science13:45 – NIH’s critical role in FDA-approved drugs17:00 – Academic research vs. commercialization pipelines20:15 – Who’s affected most? Young researchers & labs23:00 – Global ripple effects & talent displacement27:00 – Why traditional VC can’t fill the gap30:10 – DeSci as a market structure for resilient funding32:45 – Are universities ready for DeSci?35:20 – Connecting scientists with global communities37:10 – Science as public purpose and personal mission40:00 – How you can get involved in the DeSci movement🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to: Aaron Weaver : https://x.com/RealAaronWeaverJillian Casalini : https://x.com/JillianCasalini______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

What if your next spine surgery was coordinated by a DAO?In Episode 48 of the Molecule Podcast, we’re joined by Vincent Challier, spine surgeon and co-founder of SpineDAO, and Virginie Lafage, medical strategist and Core Team member, to explore how decentralized science can transform a field as specialized and critical—as spinal health.SpineDAO is building one of the first focused medical DAOs on the Bio Launchpad. In this episode, we cover:• Why spinal health is overlooked in innovation• The power of patient and clinician-led DAOs• Challenges of onboarding medical professionals into DeSci• Real-world use cases for DAOs in healthcare• Why Solana? Technical decisions behind the DAO’s designWhether you’re into biotech, DAOs, or the future of decentralized medicine, this conversation bridges science, surgery, and Web3 in a way you’ve never heard before.⏱️ Timestamps 0:00 – Intro: Meet Vincent & Virginie from SpineDAO2:10 – How they met and started the DAO5:18 – From spine surgery to decentralization: Why this field?8:50 – Building a community around spine health12:42 – Why spinal innovation is long overdue17:20 – Challenges patients face in current medical systems24:10 – How DAOs can unlock patient-centric research29:45 – Engaging surgeons and clinicians in DeSci36:30 – Building accessibility into Web3 onboarding40:00 – Why SpineDAO chose Solana44:23 – The Bio Launchpad auction and what’s next49:04 – A message to their future community52:10 – The real-world use case for SpineDAO______🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]_________Special thanks to: Vincent Challier : https://x.com/challaireVirginie Lafage : https://x.com/VirginieLafageElla McCarthy-Page :https://x.com/EMcCarthyPage______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

What if we could reinvent intellectual property for science? In this episode of Molecule’s DeSci Podcast, Kevin Noessler - Product Head at Molecule - joins us to talk about the next frontier of DeSci Science: Proof of Invention.Kevin unpacks how Molecule is building infrastructure for decentralized IP creation, ownership, and attribution. This episode zooms in on how DeSci tools can validate and tokenize early-stage scientific ideas—before patents or papers.We cover:• Kevin’s background and his role in shaping Molecule’s product roadmap• What “Proof of Invention” really means—and how it works onchain• Rethinking IP and scientific reputation through cryptographic primitives• UX challenges when designing for biotech DAOs• The difference between building SaaS vs protocols in DeSci• How open-source values translate into credible scientific infrastructureWhether you’re an innovator, researcher, or builder—this episode is a roadmap for the future of intellectual property in science.⏱ Timestamps:00:00 - Intro01:10 - Kevin’s background & journey to Molecule05:00 - What does a Product Head do in a decentralized org?09:20 - SaaS vs Protocol: Rethinking product building13:00 - Contributors, not customers: the shift in stakeholder models17:15 - UX challenges for onchain science tools21:40 - What makes a product work in DeSci?26:00 - Building with researchers in mind30:30 - Kevin’s long-term vision for Molecule35:00 - Advice for builders entering DeSci39:20 - Outro ________🔔 Subscribe to stay updated: https://www.youtube.com/@Molecule_dao/?sub_confirmation=1______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected]______Special thanks to: - Kevin Noessler: https://x.com/Noesslek- Ella McCarthy-Page: https://x.com/EMcCarthyPage______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone

What if the future of science and biotech was built on legal frameworks that empower communities, not corporations?In Episode 44 of the Molecule Podcast, we sit down with Jesse Hudson — lawyer, anthropologist, and Chief Legal Architect at Molecule. Jesse is a pioneer in building legal infrastructure for decentralized science (DeSci), DAOs, and intellectual property (IP) tokenization.This episode dives deep into:- The failure of the current global IP system- IP as cultural infrastructure- IP tokenization and why it matters for DAOs- Licensing, enforcement, and the problem of patent trolls- How indigenous IP and cultural property are being reclaimed through blockchain- New models for governance, dispute resolution, and community-owned IPJesse’s unique experience working with Amazonian tribes, biotech DAOs, and legal DAOs brings one of the most profound and ethical perspectives to the DeSci conversation.Timestamps:0:00 – Intro: Why IP matters2:13 – Meet Jesse Hudson: Legal architect & anthropologist5:05 – From anthropology to biotech DAOs7:44 – IP in the digital age: Why it’s grown 70x11:02 – How IP impacts individuals: NIL rights & personal brands15:10 – IP basics: Trademark, copyright, patents20:05 – Patent trolls & the licensing problem27:01 – Is the IP system serving the public?30:10 – Tesla & IP strategy: When to share vs protect33:42 – DAOs as IP holders: SideDAO & decentralized licensing36:10 – IP tokens & collective governance38:18 – Indigenous cultural IP: Working with the Shipibo tribe44:20 – NFT royalties & licensing for indigenous art48:52 – IP ethics: Alternative models beyond Western frameworks53:22 – DAO-based dispute resolution & legal evolution59:50 – Closing thoughts: Cultural values driving IP systems🔗 Learn more at https://molecule.xyz

The psychedelic industry is booming, but a major battle is unfolding: Who will control the future of these powerful medicines? Will open science prevail, or will corporations dominate through patents? In this episode, we sit down with Graham Pechenik, a leading expert in psychedelic patent law, to unravel the complexities of intellectual property in the space.Graham Pechenik is the founder of Calyx Law, a law firm specializing in psychedelic and cannabis patents. With a background in neuroscience and law, he provides deep insights into the legal landscape shaping the future of psychedelic medicine.Topics Discussed:• The role of patents in psychedelic research• Controversies around corporate control and monopolization• How open-source models could challenge big pharma• What legal battles mean for researchers, startups, and patients• The future of psychedelic accessibilityTune in to get expert insights from one of the leading voices in psychedelic IP law.______If you prefer listening to podcasts on audio apps, feel free to search for "The DeSci Podcast" on Spotify, Google Podcasts & Apple Podcasts. You'll also find all links to the podcast apps below.If you want to join us on the show as a speaker or have guest ideas, please shoot us an mail at [email protected] thanks to: Ella McCarthy-Page - https://x.com/EMcCarthyPageGraham Pechenik - https://x.com/calyxlaw______Let's connect: Website: https://bit.ly/3d6nh2CTwitter: https://twitter.com/Molecule_daoDiscord: https://discord.gg/ZHGpJQzeTqMolecule - The future of medicine belongs to everyone