New Medicines from Evolutionary Pathways: Using Comparative Genomics to Treat Human Disease | Talking Precision Medicine #33

In this episode Genialis CEO Rafael Rosengarten sat down with Dr. Carolina Haefliger, head of translational medicine at Debiopharm, the privately held Swiss biopharma company focused on oncology drug development. They talked about de-risking promising new cancer drugs, and what it takes from the science to the team to the technologies. Episode 35 links: Visit ⁠⁠⁠TPM E35⁠⁠⁠ for highlights and links from this episode > Learn more about Genialis™ krasID > New Genialis RNA Biomarker Accurately Predicts KRAS Outcomes in Lung Cancer Patients >

Today we turn the mic around, as our guest Adam Stasio hosts an excellent podcast of his own. Adam’s day job, however, is running SciMed, a boutique life sciences software development company. Adam and Genialis CEO Rafael Rosengarten discuss the state of scientific software, the importance of agility and communication, and approaches to building a lasting company culture. Visit ⁠⁠TPM E34⁠⁠ for highlights and links from this episode.

Our guest today is Dr. Ashley Zehnder, co-founder and CEO of Fauna Bio. Fauna is a revolutionary young biotech company using comparative genomics of an array of non-traditional mammalian models to discover new therapeutic opportunities for people. What do ground squirrels have to do with treating battlefield trauma? Only one way to find out … Visit ⁠TPM E33⁠ for highlights and links from this episode.

In this episode, Genialis CEO Rafael Rosengarten sits down with Ajay Gopal, CEO and founder of Rx Studio. Rx Studio is a technology company using data science to tackle a major limitation to personalized medicine: drug dosing. Visit TPM E32 for highlights and links from this episode.

In this episode, Genialis CEO Rafael Rosengarten speaks with BCG management consultant and healthcare innovation expert Amy MacDougall. They discuss emerging trends in healthcare, the role of AI, ethics and more, as well as BCG’s recently released 50 Most Innovative Companies List. Visit TPM E31 for highlights and links from this episode.

This episode, Genialis’ thirtieth, is a bit different from the previous ones. CEO Rafael Rosengarten has not one, not two, but three guests, including the entire leadership team at Genialis. The gang discusses Genialis’ twin quests to build a great place to work and a business that makes a positive impact on the world.  Visit TPM E30 for highlights and links from this episode.

Our guest this episode is Dr. Susanna Harris, community lead at Vibe Bio. Susanna is a dedicated scientific communicator and an outspoken advocate for the mental health of PhD students and other science researchers. She has chronicled her journey from the academic lab bench to a venture incubator to a promising biotech company for a substantial social media following, and joins us today to dive into these topics and more. Visit TPM E29 for highlights and links from this episode.

In this episode, our host and Genialis CEO Rafael Rosengarten spotlights Vibe Bio. Vibe Bio is a new biotech aiming to disrupt how we finance drug development through stakeholder communities and cryptocurrency, starting in the rare disease arena. Our guest is Alok Tayi, co-founder and CEO of Vibe. Alok is a successful serial entrepreneur and a rare disease community member. Visit TPM E28 for highlights and links from this episode.

This episode features Jason Springs, co-founder and CEO of Endpoint Health, an ascendant precision therapeutics company. Jason is a serial entrepreneur, who with the co-founders of his previous company, is building Endpoint Health to bring together under one roof the data science, diagnostics and therapeutics necessary to achieve truly personalized care. Visit TPM E27 for highlights and links from this episode.

In this episode 26, our host Rafael sits down with Harry Glorikian. Harry is an investor, author, podcaster and veteran of the healthtech industry. Harry walks us through his latest book, The Future You, and expounds on the ways that wearable devices, personal health data and artificial intelligence are changing healthcare as we know it. Visit TPM E26 for highlights and links from this episode.