Sam Miller Science podcast

S 931: The Prevalence of Polypharmacy: Why 25% of Adults Take 5+ Prescriptions and the State of Western Medicine

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Roughly 1 in 4 American adults are taking 5 or more prescription medications at the same time, and that number climbs steeply for people over 40, for postpartum women, and for anyone managing more than one chronic condition. The most talked about murder trial of the year has put a public face on what polypharmacy looks like at its most extreme. I break down the polypharmacy conversation, walking through why national health systems in the UK, Scotland, Ireland, and the US have all written formal frameworks for managing the medication burden, why that alone tells you this is the standard rather than the exception.


Topics discussed:

- The 1 in 4 American Polypharmacy Statistic

- National Frameworks for Managing Medication Burden

- The Prescription Cascade in Younger Women

- The Endocrine and Psychiatric Overlap

- Postpartum Thyroid Conditions and Depression

- The Thyroid-to-Prolactin Cascade

- Nutrient Deficiencies That Look Like Depression

- The Lab Panel to Run Before Prescribing


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