
In this episode of Reset Recharge, Dr. Komal Patil-Sisodia explores a groundbreaking study that reveals how menopause hormone therapy (MHT) may actually reduce the risk of type 2 diabetes in perimenopausal women with prediabetes.
Dr. Komal unpacks the data from a major Diabetes and Metabolism study of over 6,500 women aged 46–60, showing that those who used hormone therapy were 30% less likely to develop diabetes. She explains the science behind how estrogen supports metabolic health — improving insulin sensitivity, lowering inflammation, reducing central fat gain, and supporting pancreatic function — and why timing, age, BMI, and ethnicity make all the difference.
You’ll learn:
- How estrogen affects blood sugar and fat distribution
- Why MHT works best when started near menopause
- Which hormone formulations and delivery routes are safest and most effective
- Why personalized, evidence-based care is key to menopause medicine
Whether you’re navigating perimenopause, supporting patients, or simply curious about hormone health, this episode breaks down complex science into practical takeaways you can use.
💡 Key takeaway: Menopause hormone therapy isn’t just about symptom relief — it can be metabolic protection for the right woman, at the right time.
Connect with me:
Eastside Menopause & Metabolism
Time Stamps:
00:00 – 00:54 | Welcome & Episode Overview Â
00:55 – 02:30 | The Study That Sparked the Conversation Â
02:31 – 04:00 | Who Benefits Most from Hormone Therapy Â
04:01 – 06:00 | How Estrogen Supports Metabolic Health Â
06:01 – 07:45 | The Timing Hypothesis Explained Â
07:46 – 09:15 | Type & Route of Hormone Therapy Matter Â
09:16 – 10:45 | Balancing Benefits and Risks Â
10:46 – 12:15 | The Takeaway: Personalized Menopause Care Â
12:16 – 13:06 | Closing & Next Steps
References:
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