NFL Week 2 DraftKings Picks 2025 | Best DFS Lineups, Ownership & Pick’em Plays

Pat Mayo updates his 2025 Fantasy Football Week 2 rankings with the latest news and goes through the Week 2 NFL Injury Report telling you who is in and out and which players stand to benefit. Mayo then goes through his favorite Week 2 Props and fills out an Underdog Pick’em Entry before getting to his Top Cheap Plays on DraftKings for Week 2 at each position. WEEK 2 PLAYER RANKINGS: https://mayomedia.substack.com/p/week-2-rankings-injuries-tidbitsFREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayoUse code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a Deposit BONUS Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH #NFL #NFLPicks #NFLProps #UDPartner #FantasyFootball  JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics. FOLLOW MAYO MEDIA NETWORK Newsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE:  https://bit.ly/YTMMN Show Index00:00 INTRO1:55 Injuries & Updated Rankings16:08 Week 2 Underdog Pick’em Entry + Week 2 Player Props30:37 Week 2 DraftKings Ownership by Position + Value Plays Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

NFL is back! In this video, Pat Mayo, Erik Beimfohr and John Breslin of 4for4 DFS Fantasy break down the best 2025 NFL Week 2 DraftKings picks, lineups, and DFS strategy to help you build winning rosters. We cover ownership projections, game stacks, top plays, fades, and Underdog Pick’em picks for Week 2. Whether you’re entering GPPs or cash games, this guide has you covered. FREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayoUse code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a the PME Exclusive Boosts at Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics.POLICYGENIUS -- Secure your family’s future with Policygenius. Head to policygenius.com/MAYO to compare free life insurance quotes from top companies and see how much you could save.FOLLOW MAYO MEDIA NETWORK Newsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE:  https://bit.ly/YTMMN #NFL #NFLDFS #UDPartner #DraftKings #NFLPicks #FantasyFootball  #NFLWeek2 Show Index00:00 Intro00:54 Week 1 Recap8:03 Key Injuries13:28 Leverage/Ownership23:50 Optimal Lineup30:21 Cheap DST38:22 DAL/NYG50:01 CIN/JAX59:38 BAL/CLE1:16:37 BUF/NYJ1:227:01 OTHER GAME SKINNY STACKS Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Get ready for NFL Week 2 best bets, teasers, and expert picks with Pat Mayo, Rob Pizzola, and Cam Stewart. We break down the full 2025 NFL Week 2 slate, with betting analysis, game previews, and our favorite teaser plays. Whether you’re looking for sharp betting edges, insights on key matchups, or value picks, this Week 2 betting guide has you covered.FREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayoUse code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a Deposit BONUS Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH #NFL #NFLPicks #udpartner #FantasyFootball #Football #Sports #BEttingJOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics.POLICYGENIUS -- Secure your family’s future with Policygenius. Head to policygenius.com/MAYO to compare free life insurance quotes from top companies and see how much you could save.od FOLLOW MAYO MEDIA NETWORKNewsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE: https://bit.ly/YTMMN Show Index00:00 Intro5:23 PICKS RECAP10:55 Gold Picks38:22 Silver Picks57:01 Bronze Picks1:09:15 Cams fastest Minute1:11:19 Teaser Picks1:13:47 Survivor Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Pat Mayo, Geoff Fienberg and Tim Anderson go game-by-game and make their 2025 Week 2 Spread Picks, Bets, Survivor Picks, and Props. Plus, a mini Cust Corner on Construction Delays & Grocery Flyers. 25% All NFL Tools Packages at https://www.4for4.com/mayoUse code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a Deposit BONUS at Coolbet: https://shorturl.at/CHfyWSubscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics.POLICYGENIUS -- Secure your family’s future with Policygenius. Head to policygenius.com/MAYO to compare free life insurance quotes from top companies and see how much you could save. FOLLOW MAYO MEDIA NETWORK Newsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE:  https://bit.ly/YTMMN #Week2 #NFLBets #NFL #NFLpicks #AFC #udpartner SHOW INDEX00:00 INTRO14:31 PICKS RECAP16:41 WAS/GB (TNF)29:15 NE/MIA38:02 NYG/DAL45:50 CHI/DET49:16 LAR/TEN52:14 BUF/NYJ1:01:13 SF/NO1:05:40 SEA/PIT1:18:27 CLE/BAL1:25:01 JAX/CIN1:31:51 CUST CORNER1:55:05 DEN/IND2:00:44 CAR/ARZ2:04:36 PHI/KC2:08:05 ATL/MIN (SNF)2:11:35 TB/HOU (MNF)2:15:47 LAC/LV (MNF)2:25:58  SUPERLOCKS/SURVIVOR2:28:15  CUST FREE MONEY Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

**2025 NFL Week 2 Fantasy Football** is underway! Pat Mayo, Jake Ciely & Ian Hartitz break down everything you need to set your best lineup and win your matchup. From player rankings to sleeper calls, we’ve got you covered. 25% All NFL Tools Packages at https://www.4for4.com/mayoUse code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a Deposit BONUS Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics.POLICYGENIUS -- Secure your family’s future with Policygenius. Head to policygenius.com/MAYO to compare free life insurance quotes from top companies and see how much you could save. GET MAYO’S RANKINGS CHEATSHEET (SENT FREE on WEDNESDAY AFTERNOON) https://mayomedia.substack.com/GET IAN’S RANKINGS & 20% off Fantasy Life Premium Packages use code "Ian”: https://www.fantasylife.com/pricingJAKE'S RANKINGS ON THE ATHLETIC: https://www.nytimes.com/athletic/6523411/2025/07/30/fantasy-football-2025-rankings-overall-positional-ppr/ FOLLOW MAYO MEDIA NETWORKNewsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE:  https://bit.ly/YTMMN  #UDPartner #FantasyFootball #NFLWeek1 #StartSit #2025NFL #FantasyRankings #SleeperPicks #PatMayo #JakeCiely #IanHartitz Show Index00:00 Intro 1:53 RB Rankings 38:31 WR Rankings 1:02:52 TE Rankings 1:09:05 QB Rankings/Streamers 1:12:35 DST Streamers  1:16:41 Q&A Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Pat Mayo and Alex Blickle preview the course and run through the odds while making their Procore Championship 2025 Picks, Bets, DraftKings Selections. Then they move into the stacked field at Wentworth for their BMW PGA Championship Picks and Bets before moving to the Ryder Cup.Get 25% off the Rabbit Hole at https://betspertsgolf.com/mayo with code “MAYO”FREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayo$500K NFL Survivor ($50 Per Entry): https://bit.ly/mayo-survivor Use code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a Deposit BONUS Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH #PGA #Golf #GolfPicks  #BMWPGAChampionship #ProcoreChampionship #rydercup #udpartner JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics.POLICYGENIUS -- Secure your family’s future with Policygenius. Head to policygenius.com/MAYO to compare free life insurance quotes from top companies and see how much you could save. FOLLOW MAYO MEDIA NETWORKNewsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE: https://bit.ly/YTMMNSHOW INDEX00:00 Intro1:47 Procore Championship42:27 BMW PGA Championship1:04:45 Bets Recap1:07:28 Ryder Cup Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Pat Mayo, Ryan Noonan and Conner Allen from 4for4 and Betsperts break down the biggest storylines with the 2025 NFL Week 1 Recap , top waiver wire pickups for fantasy football, and preview Monday Night Football: Chicago Bears at Minnesota Vikings FREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayo$500K NFL Survivor ($50 Per Entry): https://bit.ly/mayo-survivorUse code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a the PME Exclusive Boosts at Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH #NFL #NFLPicks #NFLWeek2 #waiverwire #UDPartner  JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics.POLICYGENIUS -- Secure your family’s future with Policygenius. Head to policygenius.com/MAYO to compare free life insurance quotes from top companies and see how much you could save. FOLLOW MAYO MEDIA NETWORK Newsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE:  https://bit.ly/YTMMN INDEX00:00 Intro00:41 Week 1 Betting Recap5:01 CIN/CLE10:09 BAL/BUF35:35 Fools Golf Week 1 Teams1:07:02 Week 1 Waiver Pick Ups1:18:10 MNF Bets Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Pat Mayo provides the NFL Week 1 recap with Tim Anderson and Chris Meaney breaking down the biggest takeaways from the first slate of games, giving their early guesses at the NFL Week 2 spreads. Plus — a hilarious (maybe) edition of Cust Eats featuring the Pickle KFC Combo!FREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayo$500K NFL Survivor ($50 Per Entry): https://bit.ly/mayo-survivor Use code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a the PME Exclusive Boosts at Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH #NFL #NFLPicks #NFLWeek2 #UDPartner  JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.ZBIOTICS — Go to  https://zbiotics.com/PATMAYO and use PATMAYO at checkout for 15% off any first time orders of ZBiotics probiotics.POLICYGENIUS -- Secure your family’s future with Policygenius. Head to policygenius.com/MAYO to compare free life insurance quotes from top companies and see how much you could save. FOLLOW MAYO MEDIA NETWORK Newsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE:  https://bit.ly/YTMMN INDEX00:00 Intro00:55 Jets7:34 Week 1 Recap24:34 Cust Eats KFC Pickle Combo31:48 Worst Decisions of The Week44:28 A-Block/Biggest Stories of The Week51:04 Week 2 Spread Guesses Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

Pat Mayo updates his 2025 Fantasy Football Week 1 rankings with the latest news and goes through the Week 1 NFL Injury Report telling you who is in and out and which players stand to benefit. Mayo then goes through his favorite Week 1 Props and fills out an Underdog Pick’em Entry before getting to his Top Cheap Plays on DraftKings for Week 1 at each position. FREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayo$500K NFL Survivor ($50 Per Entry): https://bit.ly/mayo-survivor 👉 Like & Subscribe + Drop your and drop your Week 1 picks in the comments  to get in a draw for $250 CASH!!!! Use code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a Deposit BONUS Coolbet: https://shorturl.at/CHfyW Subscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH#UDPartner JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.CHUBBIES — Your new wardrobe awaits! Get $10 off @chubbies with the code MAYO at https://www.chubbiesshorts.com/MAYO #chubbiespod FOLLOW MAYO MEDIA NETWORKNewsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE:  https://bit.ly/YTMMN Show Index00:00 INTRO00:44 Sub2:58 Injuries & Updated Rankings9:01 Week 1 Underdog Pick’em Entry + Week 1 Player Props25:20 Week 1 DraftKings Ownership by Position + Value Plays Message and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)

NFL is back! In this video, Pat Mayo, Tyler Tamboline and John Breslin of 4for4 DFS Fantasy break down the best 2025 NFL Week 1 DraftKings picks, lineups, and DFS strategy to help you build winning rosters. We cover ownership projections, game stacks, top plays, fades, and Underdog Pick’em picks for Week 1. Whether you’re entering GPPs or cash games, this guide has you covered. FREE WEEK + 25% OFF NFL BETTING TOOLS & PACKAGES at https://www.4for4.com/mayo$500K NFL Survivor ($50 Per Entry): https://bit.ly/mayo-survivor Use code “MAYO” at underdog and make a $5 Pick’em entry and instantly get $50 in your accountGet a Deposit BONUS Coolbet: https://shorturl.at/CHfyWSubscribe, Rate and ReviewApple: http://bit.ly/PMEiTunesSpotify: https://goo.gl/VboemH #UDPartner JOHNNIE WALKER — To claim a customized Blue Label Sunday Golf Bag by Devereux Go to johnniewalker.com/blue-in-waterBETTERHELP — Visit BetterHelp.com/PATMAYO today to get 10% off your first month.CHUBBIES — Your new wardrobe awaits! Get $10 off @chubbies with the code MAYO at https://www.chubbiesshorts.com/MAYO #chubbiespod FOLLOW MAYO MEDIA NETWORKNewsletter: https://mayomedia.substack.com/Instagram: https://www.instagram.com/mayomedianetwork/TIK TOK: https://www.tiktok.com/discover/mayo-media-networkYOUTUBE: https://bit.ly/YTMMN Show Index00:00 Intro00:41 TNF Takeaways16:51 Week 1 DK Main Slate Overview19:27 Optimal + CLE/CIN42:11 MIA/IND54:05 DEN Stack59:51 WAS/NYG1:07:46 ARZ/NOMessage and data rates apply. Must be 18+ (21+MA & AZ, 19+ AL, NE) and present in a state where Underdog Fantasy operates. Terms apply. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369)