Episode 10 - Gene Therapy

In this week's episode, Sienna and Amr get into the nitty gritty details of publishing in today's modern peer review system. We discuss many of the problems that come with this traditional system, the exciting new solutions researchers' have come up with, and our own thoughts and solutions too!   https://linktr.ee/notyetadr   Edited by: Amr   Questions or Suggestions? Email us at [email protected]

In Alastair’s final episode of this season, he describes what the heck he actually DID for his PhD; including soil contamination, bioaccessibility, and inductively coupled plasma mass spectrometry! https://linktr.ee/notyetadr Edited by: Sienna Questions or Suggestions? Email us at [email protected]

Looking to the future of therapeutics, the PhD 3 take a deep dive into gene replace therapy. Amr walks us through how scientists have developed novel means for the delivery of new functional genes into patients with rare diseases caused by mutations in in their DNA. As an recent example, we also explore the recently FDA approved gene therapy for a fatal disease known as spinal muscular atrophy (SMA). https://linktr.ee/notyetadr Edited by: Sienna Questions or Suggestions? Email us at [email protected]

In today's episode, a couple of fun guys talk about fungi! Learn all about how fungi play Catan, trade on the carbon marketplace, infect ants, and alter brain connectivity as Sienna leads us through the weird and wonderful world of these creatures. https://linktr.ee/notyetadr Edited by: Amr Questions or Suggestions? Email us at [email protected]

In a future where blood is currency and humans are born only if their DNA makes them genetically superior. Our inferior protagonist attempts to make his way to space, fighting the last -ism left... Genoism. https://linktr.ee/notyetadr Edited by: Alastair Questions or Suggestions? Email us at [email protected]

What makes foods spicy, and what's the science behind the small organic molecule responsible? More importunely, How can we beat the heat!? This week Alastair shares the chemistry, research, and even a fun science experiment using capsaicin!   https://linktr.ee/notyetadr   Edited by: Amr   Questions or Suggestions? Email us at [email protected]

Guy Fieri isn't the only one going to flavour town! In this episode, Sienna teaches us about how taste is made up and how our tongues (and brains) discern sweet from sour. By the end, you're going to be hankering for some mock apple pie!    https://linktr.ee/notyetadr   Edited by: Amr   Questions or Suggestions? Email us at [email protected]

What the heck even IS blue raspberry? Is it even a berry? Are they that electric shade of blue? This week, Alastair shares with Sienna and Amr the chemistry and history of this unique flavour and colour combination.   https://linktr.ee/notyetadr   Edited by: Sienna   Questions or Suggestions? Email us at [email protected]

A remarkable study published this past week about using microelectrode arrays to allow a patient with locked-in syndrome to communicate. Learn with us about how scientists used neurofeedback training to optimize a software with the patient to let them select letters and spell out words, and what they ended up using it to say! This is some really exciting work, and we are excited to share it with you all.   https://linktr.ee/notyetadr   Edited by: Alastair   Questions or Suggestions? Email us at [email protected]

This week, our new host Amr is rethinking his choices and considering wiping the slate clean. Amr teaches us about the epigenome and how it guys our cell's trajectories and fates. He also tells about how aging effects our epigenome and describes a recently published work on how we can wipe out these age-related changes and give our cells a new chance at life!   https://linktr.ee/notyetadr   Edited by: Alastair   Questions or Suggestions? Email us at [email protected]