HRX NeXt Episode 4: A Conversation about Optimizing Clinical Operations with AI

Live from HRX Live 2026, Drs. Nino Isakadze, Matt Kalscheur, and Krishna Pundi explore the role of digital health tools in addressing lifestyle risk factors and improving outcomes for patients with atrial fibrillation (AFib). They discuss the connection between AFib and modifiable risk factors, including smoking, high blood pressure, obesity, and other lifestyle-related conditions, as well as the importance of helping patients better understand their diagnosis and available treatment options. The conversation examines the challenges of encouraging meaningful lifestyle changes and how digital health tools can help clinicians engage patients, support behavior modification, and promote long-term risk factor management. From identifying opportunities for intervention to empowering patients to take a more active role in their care, the speakers highlight how technology can serve as an important pathway toward improving AFib management and advancing more proactive, patient-centered cardiovascular care. Explore the Article in the Heart Rhythm Journal: Digital health tools for patient-centered lifestyle and risk factor modification in atrial fibrillation management Article Authors and Podcast Contributors Podcast Contributors: Nino Isakadze, MD, MHS | Johns Hopkins Medicine Matt Kalscheur, MD | University of Wisconsin Krishna Pundi, MD | Stanford Medicine Listen on: Spotify Apple Podcasts iHeartRadio

In this episode, Dr. David DeLurgio, Dr. Ambrose Panico, and Dr. Stanislav Weiner explore the innovations and workflow advancements shaping the future of electrophysiology. Drawing from real-world clinical experience, they discuss emerging technologies designed to improve procedural efficiency, enhance operator control, and support more consistent outcomes in the EP lab. The conversation examines the factors that drive adoption of new devices and workflows, including safety, reliability, reproducibility, and economic value. From transseptal access and catheter navigation to broader considerations around workflow optimization, the experts share practical insights into how meaningful innovation can help clinicians deliver high-quality care while improving efficiency in everyday practice. This episode is powered by Synaptic Medical: Synaptic is an innovative medical technology company dedicated to advancing electrophysiology through a growing portfolio of thoughtfully designed solutions, including the AccuSafe transseptal guidewire, Navigo™ steerable sheath, RithmID CS catheter, and more. By working alongside physicians and healthcare partners, we aim to enhance procedural safety and efficiency, improve patient outcomes, and deliver meaningful clinical and economic value. Our mission is to help shape the future of EP with innovations that benefit patients, providers, and the broader healthcare system.  Article Authors and Podcast Contributors Podcast Contributors: David Delurgio, MD | Emory Healthcare Ambrose F Panico, DO | Cardiovascular Associates of Mesa Stanislav Weiner, MD | CHRISTUS Mother Frances Hospital Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

In this episode, Dr. Tina Baykaner, Dr. Peter Noseworthy, and Dr. Lior Jankelson explore how AI is helping clinicians manage growing volumes of clinical data and extract meaningful insights from ECGs and electronic health records. The conversation highlights emerging tools like AI-driven dashboards and decision support systems that can surface the right information at the right time. The panel also discusses where AI is already influencing clinical practice — from rhythm detection to patient selection for procedures — while emphasizing that these tools are most powerful when they support, not replace, clinical judgment. Read the full article discussed in this podcast here: Implementing AI in clinical practice: Practical insights on integrating AI through digital dashboards and beyond - Heart Rhythm Article Authors and Podcast Contributors Article Authors: Tina Baykaner, MD, FHRS Peter A. Noseworthy, MD, FHRS Elaine Y. Wan, MD, FHRS Podcast Contributors: Tina Baykaner, MD, MPH Peter A. Noseworthy, MD, FHRS Lior Jankelson, MD, PhD Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

In this episode, Dr. Michael Rosenberg and Dr. Neal Bhatia explore how burnout is hitting cardiology hard — electrophysiologists included. In this episode, we explore what artificial intelligence will actually look like in the next 5–10 years and tackle the big questions: is AI replacing physicians or redefining their role, and will AI help alleviate burnout? From generative AI to workflow automation, our experts break down how thoughtfully implemented technology can reduce cognitive load, ease administrative burden, and help EPs focus on what matters most — delivering better patient care while reclaiming professional fulfillment. Read the full article discussed in this podcast here: Avoiding burnout from AI in busy clinical practice - Heart Rhythm Article Authors and Podcast Contributors Article Authors: Varun Ayyaswami, MD Allen Chang, MD Podcast Contributors: Michael Rosenberg, MD Neal Kumar Bhatia, MD Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

In this episode, Dr. Peter Noseworthy, Dr. Christopher C. Cheung, and Dr. G. Stuart Mendenhall explore how wearable medical devices, health apps, and other digital health tools are transforming care while also creating a growing challenge of data overload for clinicians and health systems. The conversation will focus on how unprecedented volumes of patient-generated data raise concerns around accuracy, validation, and equity, and how poorly managed data streams can contribute to alert fatigue and inefficiency rather than better care. Panelists will discuss the need for robust standards to vet consumer-grade devices, as well as strategies for aggregating and prioritizing data from disparate sources using interoperability frameworks and AI-enabled triage. The episode will also examine why human oversight remains essential in managing data overload, particularly for interpreting edge cases and aligning insights with patient preferences. Ultimately, the discussion will highlight practical approaches for turning overwhelming amounts of digital health data into actionable, clinically meaningful information that improves outcomes. Read the full article discussed in this podcast here: Managing data overload: AI, wearables, and apps - Heart Rhythm Article Authors and Podcast Contributors Article Authors: Christopher C. Cheung, MD, MPH Hawkins Gay, MD G. Stuart Mendenhall, MD, FHRS Podcast Contributors: Peter Noseworthy, MD, MBA Christopher C. Cheung, MD, MPH G. Stuart Mendenhall, MD, FHRS Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

In this episode, Dr. Krishna Pundi and Dr. Michael Rosenberg discuss a timely paper focused on how clinicians can practically engage with artificial intelligence while managing busy clinical schedules. They explore why developing a working understanding of AI is becoming increasingly important, how to evaluate clinical and consumer AI tools with confidence, and ways clinicians can stay ahead of rapid innovation without feeling overwhelmed. The conversation offers practical guidance for using AI thoughtfully in everyday practice and responding to questions from patients, colleagues, and health system leaders.   Read the full article discussed in this podcast here: Learning AI for busy clinicians: Staying ahead - Heart Rhythm Article Authors and Podcast Contributors Article Authors: Sanjiv M. Narayan MD, PhD, FHRS Emma Svennberg MD, PhD Podcast Contributors: Krishna Pundi, MD Michael Rosenberg, MD Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

What exactly is artificial intelligence — and why should clinicians care? In this episode, Dr. Neal Bhatia joins Dr. Collin M. Stultz to discuss the Heart Rhythm article "What is AI and why should I care?" and break down the fundamentals of AI in a clear, practical way. They explore what AI really means in the context of cardiovascular care, how it's already being applied in medicine, and what clinicians should understand as these tools become more integrated into everyday practice. A concise, accessible conversation on why AI matters now — and what's ahead. Read the full article discussed in this podcast here: What is AI and why should I care? - Heart Rhythm Article Authors and Podcast Contributors Article Authors: Collin M. Stultz, MD, PhD Podcast Contributors: Collin M. Stultz, MD, PhD Neal Kumar Bhatia, MD Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

Description Artificial intelligence continues to reshape the health care landscape — and cardiac electrophysiology is no exception. In this episode, we explore the rapid growth of AI across health care and take a closer look at how these technologies are being integrated into cardiac EP, with a particular focus on real-world, day-to-day clinical operations. From workflow efficiencies to decision support and patient care, our discussion examines where AI is already making an impact, the challenges of adoption, and what the future may hold for clinicians and health systems alike. Read the full article discussed in this podcast here: Optimizing clinical operations with AI - Heart Rhythm Article Authors and Podcast Contributors Article Authors: Janet K. Han, MD, FHRS Podcast Contributors: Nino Isakadzee, MD, MHS Neal Bhatia, MD Krishna Pundi, MD Janet Han, MD, FHRS Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

AI has the potential to transform healthcare through tools that streamline tasks, support diagnosis, and guide clinical decisions, but bias in these models poses risks of patient harm. This article highlights the issue of bias, its clinical consequences, and introduces a simple framework to mitigate it. Join moderator Krishna Pundi and guests Mike Rosenberg, Peter Noseworthy, and Demilade Adedinsewo for a lively discussion of this cutting-edge manuscript from heart Rhythm O2.   Podcast Contributors Krishna Pundi, MD, Stanford University/Palo Alto VA Medical Center  Mike Rosenberg, MD, FHRS, University of Colorado Anschutz  Peter Noseworthy, MD, FHRS, Mayo Clinic  Demilade Adedinsewo, MD, MPH, Mayo Clinic Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio

Artificial intelligence is seen as a promising tool for improving clinical, operational, and financial aspects of healthcare, though its impact remains largely theoretical for now. This article reviews current progress, outlines strategies for success, and emphasizes balancing innovation with responsibility to ensure benefits for both patients and clinicians.   Article Authors Thomas F. Deering, MBA, MD, FHRS, CCDS, Andrew D. Krahn, MD, FHRS, Jodie L. Hurwitz, MD, FHRS  Podcast Contributors Krishna Pundi, MD, Stanford University/Palo Alto VA Medical Center Tina Baykaner, MD, MPH, Stanford University Jason G. Andrade, MD, FHRS, Vancouver General Hospital Listen on: HRX Innovation Hub Spotify Apple Podcasts iHeartRadio