Dean's Chat - All Things Podiatric Medicine podcast

DCLS: Interdigital Web Space Infections: When to Test, When to Treat, and What to Treat

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Interdigital web space infections may seem like a routine podiatric complaint, but the underlying diagnosis can be far more complicated—and potentially serious—than it appears. In this episode of the Dean’s Chat Learning Series, 

Dr. Jeffrey Jensen and Dr. Johanna Richey welcome Dr. William Scherer, Senior Podiatric Medical Advisor and clinical consultant for Bako Diagnostics, for an in-depth discussion on the diagnosis and management of interdigital web space infections. 

The conversation challenges the common assumption that every macerated, painful web space represents tinea pedis and emphasizes the importance of distinguishing fungal, bacterial, mixed, and noninfectious causes.

Dr. Scherer discusses the differential diagnosis, with particular attention given to high-risk patients, including those with diabetes, neuropathy, or compromised vascular status, in whom a seemingly minor web space problem can progress to cellulitis, hospitalization, or even amputation. The discussion highlights how diagnostic testing can help move clinicians away from empiric treatment and toward more precise, evidence-based therapy.

The episode explores newer PCR-based diagnostic technology and how a simple superficial skin scraping can help identify bacterial, fungal, or mixed infections and provide organism-specific information. Join us, as we discuss evidence based data to influence treatment decisions and why identifying bacterial infection early is particularly important. Throughout this discussion a common theme arises of “diagnose first, then tailor treatment to the actual pathology.” By applying evidence-based medicine, appropriate diagnostic testing, and a thoughtful decision-tree approach, podiatrists can improve diagnostic accuracy and patient outcomes while continuing to advance the role of podiatry in dermatologic and infectious disease care.

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