ACIOS Study

Lyvonne Tume (Liverpool) and David Harrison (London) present the results of the GASTRIC-PICU trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. GASTRIC-PICU investigates the effect of gastric residual volume monitoring in critically ill children receiving mechanical ventilation. Srinivas Murthy (Vancouver) delivers an editorial. Marion Campbell (Aberdeen), John Dorling (Leeds) and Christopher Seymour (Pittsburgh) contribute to a panel discussion. The session is chaired by Kartryn Puxty (Glasgow). GASTRIC-PICU was simultaneously published in JAMA.

Prof Deborah Cook (Hamilton, Canada) presents the 2026 John Hinds Lecture, titled "Purpose and Passion".

Asger Grenfeldt (Aarhus) and Lars Wiuff Andersen (Aarhus) present the results of the BIHCA trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. BIHCA investigates the efficacy of sodium bicarbonate in cardiac arrest. Ary Serpa Neto (Melbourne) gives an independent editorial. Aryelly Rodriguez (Edinburgh), Kathy Rowan (London) and Angela Jerath (Toronto) contribute to a panel discussion. The session is chaired by Peter McGuigan (Belfast). BIHCA was simultaneously published in JAMA.

Stephen Macdonald (Perth), Belinda Howe (Melbourne) and Sandra Peake (Adelaide) present the results of the ARISE FLUIDS trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. ARISE FLUIDS compares two septic shock resuscitation strategies - restricted fluids and early vasopressors or a larger initial intravenous fluid volume and later vasopressors. Tine Sylvest Meyhoff (Copenhagen) delivers an independent editorial. David Harrison (London), Marlies Ostermann (London) and Israel Maia (Sao Paulo) contribute to a panel discussion. The session is chaired by Darren Taichman (Philadelphia). ARISE FLUIDS was simultaneosuly published in the New England Journal of Medicine.

Kristin Mayes (Pittsburgh) and Sachin Yende (Pittsburgh) present the results of the ACCOMPLISH trial at the Critical Care Reviews Meeting 2026 in Titanic Belfast. ACCOMPLISH investigates the effects of remote patient monitoring for preventing hospital readmission following infection and sepsis. Jo McPeake (Cambridge) delivers an independent editorial. Victoria Cornelius (London), Brenda O'Neill (Belfast) and Adriano Jose Pereira (Sao Paulo) contribute to a panel discussion. The session is chaired by Carol Hodgson (Melbourne). ACCOMPLISH was simultaneously published in JAMA Network Open.

Rob Mac Sweeney discusses the ANDROMEDA-SHOCK 2 trial with Prof Jan Bakker, one of the leads for this major international randomised controlled trial investigating peripheral perfusion guided resuscitation in septic shock

Rob Mac Sweeney discusses the Tigris Trial with chief investigator John Kellum. Tigris investigated the efficacy of polymyxin B haemoadsorption in endotoxic septic shock. It was published in Lancet Respiratory Medicine in March, 2026.

Rob Mac Sweeney discusses the ACIOS study with Tim Baker, the study lead. ACIOS is a point prevalence study describing the burden of critical illness in Africa. It was published in the Lancet in March, 2025.

Rob Mac Sweeney discusses the IVIO trial with investigators Lars Wiuff Andersen and Mikael Fink Valentine from Aarhus, Denmark. The IVIO trial compared intraosseous with intravenous vascular access in adult patients suffering an out-of-hospital cardiac arrest. It was presented at the 2024 European Resuscitation Council congress in Athens and simultaneously published in the New England Journal of Medicine.

Rob Mac Sweeney discusses the PARAMEDIC 3 trial with it's investigators Keith Couple and Ranjit Lall from the University of Warwick, England. PARAMEDIC 3 compared intravenous with intraosseous vascular access in adult patients suffering cardiac arrest and requiring drug administration during ongoing resuscitation. It was presented at the European Resuscitation Council meeting in Athens on October 31st and simultaneously published in the New England Journal of Medicine.